Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 131334542 | . | G | A | CCDS7660.2:NM_002412.3:c.119cGc>cAc_NP_002403.2:p.40R>H | Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1eh6 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | ARG | A:9 | A:9 | 143.0 | 0.636 | E | -136.1 | 153.5 | 143.0 | 0.636 | 0.0 |
HOH |
2.957 |
N |
O |
||
| 1eh7 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | ARG | A:9 | A:9 | 137.0 | 0.609 | E | -136.1 | 158.1 | 137.0 | 0.609 | 0.0 |
HOH |
2.877 |
N |
O |
||
| 1eh8 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | ARG | A:9 | A:9 | 140.0 | 0.622 | E | -125.6 | 158.0 | 140.0 | 0.622 | 0.0 |
HOH |
2.975 |
N |
O |
||
| 1yfh | 3 | P16455 | 100.0 | 1e-130 |
X-RAY |
2005-12-13 | ARG | E:9 | A:9 | 76.0 | 0.338 | E | -133.8 | 153.5 | NA | NA | NA | ||||||
| ARG | F:9 | B:9 | 41.0 | 0.182 | E | -139.6 | 149.8 | NA | NA | NA | |||||||||||||
| ARG | G:9 | C:9 | 142.0 | 0.631 | E | -121.4 | 170.0 | 142.0 | 0.631 | 0.0 | |||||||||||||
| 1t39 | 3 | P16455 | 99.44 | 5e-129 |
X-RAY |
2004-07-13 | ARG | E:21 | A:9 | 176.0 | 0.782 | E | -111.8 | 130.3 | 176.0 | 0.782 | 0.0 | ||||||
| ARG | F:21 | B:9 | 187.0 | 0.831 | -121.8 | 159.6 | NA | NA | NA | ||||||||||||||
| 1qnt | 1 | P16455 | 100.0 | 1e-128 |
X-RAY |
1999-12-16 | ARG | A:9 | A:9 | 146.0 | 0.649 | E | -136.0 | 155.6 | 146.0 | 0.649 | 0.0 |
HOH |
2.806 |
O |
O |
||
| 1t38 | 3 | P16455 | 98.88 | 6e-128 |
X-RAY |
2004-07-13 | ARG | C:21 | A:9 | 106.0 | 0.471 | E | -124.0 | 150.6 | 106.0 | 0.471 | 0.0 | ||||||
| 3kzy | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | ARG | A:12 | A:9 | 133.0 | 0.591 | E | -137.7 | 153.4 | 133.0 | 0.591 | 0.0 |
HOH |
2.769 |
N |
O |
||
| ARG | B:12 | B:9 | 127.0 | 0.564 | E | -137.5 | 138.7 | NA | NA | NA | |||||||||||||
| 3l00 | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | ARG | A:12 | A:9 | 138.0 | 0.613 | E | -124.5 | 148.9 | 138.0 | 0.613 | 0.0 |
HOH |
2.727 |
O |
O |
||
| 6sc2 | 2 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | ARG | B:9 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6sc2 | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | ARG | A:9 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6rla | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | ARG | A:9 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | B:9 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6rlb | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | ARG | A:9 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | B:9 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3kzz | 1 | ? | 88.7 | 7e-111 |
X-RAY |
2010-12-15 | ARG | A:12 | A:9 | 134.0 | 0.596 | E | -112.8 | 155.3 | 134.0 | 0.596 | 0.0 |
HOH |
4.448 |
NH1 |
O |
||
| 6y8p | 1 | E5BBQ0 | 89.14 | 4e-110 |
X-RAY |
2021-03-31 | ARG | A:7 | A:9 | 152.0 | 0.676 | E | -136.9 | 126.7 | 152.0 | 0.676 | 0.0 |
EDO HOH |
9.535 7.130 |
NH2 NH2 |
O1 O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p16455-f1 | 1 | P16455 | 100.0 | 2e-151 | ARG | A:9 | A:9 | 152.0 | 0.676 | E | -136.0 | 146.2 | |