Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 131334572 | . | T | A | CCDS7660.2:NM_002412.3:c.149cTg>cAg_NP_002403.2:p.50L>Q | Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1eh6 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | LEU | A:19 | A:19 | 0.0 | 0.0 | E | -115.2 | 125.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.040 |
CD2 |
O |
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| 1eh7 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | LEU | A:19 | A:19 | 0.0 | 0.0 | E | -108.4 | 125.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.213 |
CD2 |
O |
||
| 1eh8 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | LEU | A:19 | A:19 | 2.0 | 0.012 | E | -108.7 | 130.7 | 2.0 | 0.012 | 0.0 |
HOH |
5.852 |
O |
O |
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| 1yfh | 3 | P16455 | 100.0 | 1e-130 |
X-RAY |
2005-12-13 | LEU | E:19 | A:19 | 2.0 | 0.012 | E | -92.3 | 133.0 | NA | NA | NA | ||||||
| LEU | F:19 | B:19 | 2.0 | 0.012 | E | -94.9 | 128.6 | NA | NA | NA | |||||||||||||
| LEU | G:19 | C:19 | 2.0 | 0.012 | E | -97.6 | 129.2 | 2.0 | 0.012 | 0.0 |
XCY HOH |
8.068 9.908 |
CD2 CD2 |
NZ O |
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| 1t39 | 3 | P16455 | 99.44 | 5e-129 |
X-RAY |
2004-07-13 | LEU | E:31 | A:19 | 0.0 | 0.0 | -148.2 | 103.7 | 0.0 | 0.0 | 0.0 | |||||||
| LEU | F:31 | B:19 | 1.0 | 0.006 | -148.5 | 104.6 | NA | NA | NA | ||||||||||||||
| 1qnt | 1 | P16455 | 100.0 | 1e-128 |
X-RAY |
1999-12-16 | LEU | A:19 | A:19 | 0.0 | 0.0 | E | -114.3 | 135.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.842 |
CD2 |
O |
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| 1t38 | 3 | P16455 | 98.88 | 6e-128 |
X-RAY |
2004-07-13 | LEU | C:31 | A:19 | 0.0 | 0.0 | E | -91.1 | 122.4 | 0.0 | 0.0 | 0.0 |
HOH |
9.223 |
CD2 |
O |
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| 3kzy | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | LEU | A:22 | A:19 | 0.0 | 0.0 | E | -116.3 | 130.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.144 |
CD2 |
O |
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| LEU | B:22 | B:19 | 0.0 | 0.0 | E | -118.3 | 136.4 | NA | NA | NA | |||||||||||||
| 3l00 | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | LEU | A:22 | A:19 | 0.0 | 0.0 | E | -112.4 | 126.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.255 |
CD2 |
O |
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| 6sc2 | 2 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | LEU | B:19 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6sc2 | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | LEU | A:19 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6rla | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | LEU | A:19 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| LEU | B:19 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6rlb | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | LEU | A:19 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| LEU | B:19 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3kzz | 1 | ? | 88.7 | 7e-111 |
X-RAY |
2010-12-15 | LEU | A:22 | A:19 | 0.0 | 0.0 | E | -110.5 | 130.7 | 0.0 | 0.0 | 0.0 |
OBG HOH |
9.735 3.878 |
CD2 CD2 |
C7 O |
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| 6y8p | 1 | E5BBQ0 | 89.14 | 4e-110 |
X-RAY |
2021-03-31 | LEU | A:17 | A:19 | 2.0 | 0.012 | E | -122.7 | 109.6 | 2.0 | 0.012 | 0.0 |
OGQ EDO HOH |
9.303 8.483 6.774 |
CD2 CD2 CD2 |
CBG O2 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p16455-f1 | 1 | P16455 | 100.0 | 2e-151 | LEU | A:19 | A:19 | 0.0 | 0.0 | E | -104.3 | 130.1 | |