Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 131334604 | . | G | A | CCDS7660.2:NM_002412.3:c.181Gaa>Aaa_NP_002403.2:p.61E>K | Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1eh6 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLU | A:30 | A:30 | 62.0 | 0.326 | E | -158.5 | 151.7 | 62.0 | 0.326 | 0.0 |
ZN HOH |
8.413 2.820 |
N OE2 |
ZN O |
||
| 1eh7 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLU | A:30 | A:30 | 71.0 | 0.374 | E | -152.5 | 152.2 | 71.0 | 0.374 | 0.0 |
ZN HOH |
8.464 2.976 |
N OE2 |
ZN O |
||
| 1eh8 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLU | A:30 | A:30 | 72.0 | 0.379 | E | -153.9 | 152.9 | 72.0 | 0.379 | 0.0 |
ZN HOH |
8.471 3.418 |
N OE2 |
ZN O |
||
| 1yfh | 3 | P16455 | 100.0 | 1e-130 |
X-RAY |
2005-12-13 | GLU | E:30 | A:30 | 75.0 | 0.395 | E | -171.6 | 142.0 | NA | NA | NA | ||||||
| GLU | F:30 | B:30 | 76.0 | 0.4 | E | -170.2 | 145.0 | NA | NA | NA | |||||||||||||
| GLU | G:30 | C:30 | 71.0 | 0.374 | E | -171.3 | 144.1 | 71.0 | 0.374 | 0.0 |
XCY ZN |
5.627 8.695 |
OE2 N |
CB ZN |
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| 1t39 | 3 | P16455 | 99.44 | 5e-129 |
X-RAY |
2004-07-13 | GLU | E:42 | A:30 | 72.0 | 0.379 | -156.3 | 178.9 | 72.0 | 0.379 | 0.0 | |||||||
| GLU | F:42 | B:30 | 72.0 | 0.379 | -156.3 | 178.3 | NA | NA | NA | ||||||||||||||
| 1qnt | 1 | P16455 | 100.0 | 1e-128 |
X-RAY |
1999-12-16 | GLU | A:30 | A:30 | 74.0 | 0.389 | E | -158.1 | 148.9 | 74.0 | 0.389 | 0.0 |
HOH |
3.243 |
O |
O |
||
| 1t38 | 3 | P16455 | 98.88 | 6e-128 |
X-RAY |
2004-07-13 | GLU | C:42 | A:30 | 65.0 | 0.342 | E | -166.1 | 128.9 | 65.0 | 0.342 | 0.0 | ||||||
| 3kzy | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | GLU | A:33 | A:30 | 69.0 | 0.363 | E | -141.9 | 148.2 | 69.0 | 0.363 | 0.0 |
ZN HOH |
8.582 2.595 |
N OE2 |
ZN O |
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| GLU | B:33 | B:30 | 72.0 | 0.379 | E | -142.7 | 144.7 | NA | NA | NA | |||||||||||||
| 3l00 | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | GLU | A:33 | A:30 | 74.0 | 0.389 | E | -142.4 | 148.1 | 74.0 | 0.389 | 0.0 |
ZN HOH |
8.585 2.663 |
N OE1 |
ZN O |
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| 6sc2 | 2 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | ARG | B:30 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6sc2 | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | ARG | A:30 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6rla | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | ARG | A:30 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | B:30 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6rlb | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | ARG | A:30 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | B:30 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3kzz | 1 | ? | 88.7 | 7e-111 |
X-RAY |
2010-12-15 | GLU | A:33 | A:30 | 69.0 | 0.363 | E | -139.2 | 150.0 | 69.0 | 0.363 | 0.0 |
ZN OBG HOH |
8.586 8.465 3.514 |
N OE2 O |
ZN C8 O |
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| 6y8p | 1 | E5BBQ0 | 89.14 | 4e-110 |
X-RAY |
2021-03-31 | GLU | A:28 | A:30 | 66.0 | 0.347 | E | -132.5 | 166.3 | 66.0 | 0.347 | 0.0 |
ZN OGQ EDO HOH |
8.575 6.782 3.461 3.122 |
N OE2 OE2 OE1 |
ZN OAW C1 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p16455-f1 | 1 | P16455 | 100.0 | 2e-151 | GLU | A:30 | A:30 | 83.0 | 0.437 | E | -149.0 | 143.4 | |