Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 131506215 | . | A | C | CCDS7660.2:NM_002412.3:c.275cAg>cCg_NP_002403.2:p.92Q>P | Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1eh6 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLN | A:61 | A:61 | 50.0 | 0.278 | H | -67.4 | -37.9 | 50.0 | 0.278 | 0.0 |
HOH |
2.633 |
NE2 |
O |
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| 1eh7 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLN | A:61 | A:61 | 51.0 | 0.283 | H | -65.8 | -37.1 | 51.0 | 0.283 | 0.0 |
HOH |
2.667 |
NE2 |
O |
||
| 1eh8 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLN | A:61 | A:61 | 47.0 | 0.261 | H | -61.0 | -46.3 | 47.0 | 0.261 | 0.0 |
HOH |
2.409 |
NE2 |
O |
||
| 1yfh | 3 | P16455 | 100.0 | 1e-130 |
X-RAY |
2005-12-13 | GLN | E:61 | A:61 | 46.0 | 0.256 | H | -49.6 | -49.9 | NA | NA | NA | ||||||
| GLN | F:61 | B:61 | 50.0 | 0.278 | H | -56.8 | -51.1 | NA | NA | NA | |||||||||||||
| GLN | G:61 | C:61 | 51.0 | 0.283 | H | -55.4 | -45.0 | 51.0 | 0.283 | 0.0 | |||||||||||||
| 1t39 | 3 | P16455 | 99.44 | 5e-129 |
X-RAY |
2004-07-13 | GLN | E:73 | A:61 | 52.0 | 0.289 | H | -83.6 | -34.0 | 52.0 | 0.289 | 0.0 | ||||||
| GLN | F:73 | B:61 | 52.0 | 0.289 | H | -83.0 | -34.8 | NA | NA | NA | |||||||||||||
| 1qnt | 1 | P16455 | 100.0 | 1e-128 |
X-RAY |
1999-12-16 | GLN | A:61 | A:61 | 57.0 | 0.317 | H | -71.0 | -33.4 | 57.0 | 0.317 | 0.0 |
HOH |
2.693 |
OE1 |
O |
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| 1t38 | 3 | P16455 | 98.88 | 6e-128 |
X-RAY |
2004-07-13 | GLN | C:73 | A:61 | 47.0 | 0.261 | H | -84.6 | -40.8 | 47.0 | 0.261 | 0.0 | ||||||
| 3kzy | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | GLN | A:64 | A:61 | 51.0 | 0.283 | H | -65.9 | -36.7 | 51.0 | 0.283 | 0.0 |
HOH |
2.605 |
NE2 |
O |
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| GLN | B:64 | B:61 | 50.0 | 0.278 | H | -56.0 | -38.2 | NA | NA | NA | |||||||||||||
| 3l00 | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | GLN | A:64 | A:61 | 51.0 | 0.283 | H | -64.0 | -40.5 | 51.0 | 0.283 | 0.0 |
HOH |
2.694 |
OE1 |
O |
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| 6sc2 | 2 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | GLN | B:61 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6sc2 | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | GLN | A:61 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6rla | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | GLN | A:61 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| GLN | B:61 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6rlb | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | GLN | A:61 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| GLN | B:61 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3kzz | 1 | ? | 88.7 | 7e-111 |
X-RAY |
2010-12-15 | GLN | A:64 | A:61 | 56.0 | 0.311 | H | -61.1 | -37.9 | 56.0 | 0.311 | 0.0 |
HOH |
2.579 |
OE1 |
O |
||
| 6y8p | 1 | E5BBQ0 | 89.14 | 4e-110 |
X-RAY |
2021-03-31 | GLN | A:59 | A:61 | 39.0 | 0.217 | H | -73.6 | -28.5 | 39.0 | 0.217 | 0.0 |
HOH |
5.774 |
N |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p16455-f1 | 1 | P16455 | 100.0 | 2e-151 | GLN | A:61 | A:61 | 48.0 | 0.267 | H | -63.7 | -40.3 | |