Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 131506251 | . | C | A | CCDS7660.2:NM_002412.3:c.311cCc>cAc_NP_002403.2:p.104P>H | Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1eh6 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | PRO | A:73 | A:73 | 38.0 | 0.262 | G | -53.2 | -30.0 | 38.0 | 0.262 | 0.0 |
HOH |
3.416 |
N |
O |
||
| 1eh7 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | PRO | A:73 | A:73 | 38.0 | 0.262 | G | -53.0 | -30.8 | 38.0 | 0.262 | 0.0 |
HOH |
3.278 |
N |
O |
||
| 1eh8 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | PRO | A:73 | A:73 | 37.0 | 0.255 | G | -49.1 | -37.2 | 37.0 | 0.255 | 0.0 |
HOH |
3.724 |
N |
O |
||
| 1yfh | 3 | P16455 | 100.0 | 1e-130 |
X-RAY |
2005-12-13 | PRO | E:73 | A:73 | 25.0 | 0.172 | T | -48.4 | -12.0 | NA | NA | NA | ||||||
| PRO | F:73 | B:73 | 34.0 | 0.234 | G | -39.2 | -26.0 | NA | NA | NA | |||||||||||||
| PRO | G:73 | C:73 | 29.0 | 0.2 | T | -52.2 | -3.2 | 29.0 | 0.2 | 0.0 | |||||||||||||
| 1t39 | 3 | P16455 | 99.44 | 5e-129 |
X-RAY |
2004-07-13 | PRO | E:85 | A:73 | 16.0 | 0.11 | G | -61.1 | -12.5 | 16.0 | 0.11 | 0.0 | ||||||
| PRO | F:85 | B:73 | 16.0 | 0.11 | G | -61.4 | -13.3 | NA | NA | NA | |||||||||||||
| 1qnt | 1 | P16455 | 100.0 | 1e-128 |
X-RAY |
1999-12-16 | PRO | A:73 | A:73 | 36.0 | 0.248 | G | -54.7 | -31.3 | 36.0 | 0.248 | 0.0 |
HOH |
3.743 |
CD |
O |
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| 1t38 | 3 | P16455 | 98.88 | 6e-128 |
X-RAY |
2004-07-13 | PRO | C:85 | A:73 | 27.0 | 0.186 | G | -61.5 | -27.4 | 27.0 | 0.186 | 0.0 | ||||||
| 3kzy | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | PRO | A:76 | A:73 | 31.0 | 0.214 | G | -60.1 | -30.6 | 31.0 | 0.214 | 0.0 |
HOH |
2.726 |
O |
O |
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| PRO | B:76 | B:73 | 25.0 | 0.172 | G | -55.4 | -35.1 | NA | NA | NA | |||||||||||||
| 3l00 | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | PRO | A:76 | A:73 | 35.0 | 0.241 | G | -59.7 | -25.6 | 35.0 | 0.241 | 0.0 |
HOH |
2.730 |
O |
O |
||
| 6sc2 | 2 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | PRO | B:73 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6sc2 | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | PRO | A:73 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6rla | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | PRO | A:73 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PRO | B:73 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6rlb | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | PRO | A:73 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PRO | B:73 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3kzz | 1 | ? | 88.7 | 7e-111 |
X-RAY |
2010-12-15 | PRO | A:76 | A:73 | 35.0 | 0.241 | G | -61.3 | -25.3 | 35.0 | 0.241 | 0.0 |
HOH |
2.816 |
O |
O |
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| 6y8p | 1 | E5BBQ0 | 89.14 | 4e-110 |
X-RAY |
2021-03-31 | PRO | A:71 | A:73 | 32.0 | 0.221 | G | -67.6 | -9.0 | 32.0 | 0.221 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p16455-f1 | 1 | P16455 | 100.0 | 2e-151 | PRO | A:73 | A:73 | 36.0 | 0.248 | G | -60.9 | -26.1 | |