Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 131565064 | . | A | C | CCDS7660.2:NM_002412.3:c.520Atc>Ctc_NP_002403.2:p.174I>L | Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1eh6 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | ILE | A:143 | A:143 | 0.0 | 0.0 | B | -99.2 | 107.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.861 |
O |
O |
||
| 1eh7 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | ILE | A:143 | A:143 | 0.0 | 0.0 | B | -103.3 | 106.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.684 |
O |
O |
||
| 1eh8 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | ILE | A:143 | A:143 | 0.0 | 0.0 | B | -102.0 | 104.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.537 |
O |
O |
||
| 1yfh | 3 | P16455 | 100.0 | 1e-130 |
X-RAY |
2005-12-13 | ILE | E:143 | A:143 | 0.0 | 0.0 | S | -98.8 | 99.3 | NA | NA | NA | ||||||
| ILE | F:143 | B:143 | 0.0 | 0.0 | B | -96.9 | 101.6 | NA | NA | NA | |||||||||||||
| ILE | G:143 | C:143 | 3.0 | 0.017 | B | -99.1 | 99.5 | 3.0 | 0.017 | 0.0 |
XCY HOH |
7.708 3.385 |
O O |
CH O |
|||||||||
| 1t39 | 3 | P16455 | 99.44 | 5e-129 |
X-RAY |
2004-07-13 | ILE | E:155 | A:143 | 0.0 | 0.0 | B | -110.8 | 98.1 | 0.0 | 0.0 | 0.0 |
E1X |
6.175 |
O |
C11 |
||
| ILE | F:155 | B:143 | 0.0 | 0.0 | B | -107.6 | 97.7 | NA | NA | NA | |||||||||||||
| 1qnt | 1 | P16455 | 100.0 | 1e-128 |
X-RAY |
1999-12-16 | ILE | A:143 | A:143 | 0.0 | 0.0 | B | -100.5 | 107.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.058 |
O |
O |
||
| 1t38 | 3 | P16455 | 98.88 | 6e-128 |
X-RAY |
2004-07-13 | ILE | C:155 | A:143 | 0.0 | 0.0 | B | -88.7 | 99.6 | 0.0 | 0.0 | 0.0 |
6OG HOH |
6.880 4.321 |
O O |
C O |
||
| 3kzy | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | ILE | A:146 | A:143 | 0.0 | 0.0 | S | -90.8 | 116.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.823 |
O |
O |
||
| ILE | B:146 | B:143 | 0.0 | 0.0 | B | -95.7 | 111.2 | NA | NA | NA | |||||||||||||
| 3l00 | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | ILE | A:146 | A:143 | 0.0 | 0.0 | B | -99.8 | 110.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.637 |
O |
O |
||
| 6sc2 | 2 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | ILE | B:143 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6sc2 | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | ILE | A:143 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6rla | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | ILE | A:143 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ILE | B:143 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6rlb | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | ILE | A:143 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ILE | B:143 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3kzz | 1 | ? | 88.7 | 7e-111 |
X-RAY |
2010-12-15 | ILE | A:146 | A:143 | 0.0 | 0.0 | B | -90.3 | 110.4 | 0.0 | 0.0 | 0.0 |
OBG HOH |
6.871 3.589 |
O O |
C3 O |
||
| 6y8p | 1 | E5BBQ0 | 89.14 | 4e-110 |
X-RAY |
2021-03-31 | ILE | A:141 | A:143 | 0.0 | 0.0 | B | -87.1 | 107.3 | 0.0 | 0.0 | 0.0 |
OGQ EDO HOH |
5.812 9.548 4.050 |
O O O |
CBH C2 O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p16455-f1 | 1 | P16455 | 100.0 | 2e-151 | ILE | A:143 | A:143 | 0.0 | 0.0 | B | -88.0 | 112.1 | |