Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 131565092 . G A CCDS7660.2:NM_002412.3:c.548aGc>aAc_NP_002403.2:p.183S>N Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1eh6 1 P16455 100.0 5e-151 X-RAY
 2000-04-12 SER A:152 A:152 96.0 0.835 T -78.1 -13.3 96.0 0.835 0.0 HOH
 2.684
 O
 O
1eh7 1 P16455 100.0 5e-151 X-RAY
 2000-04-12 SER A:152 A:152 97.0 0.843 T -77.9 -11.9 97.0 0.843 0.0 HOH
 2.542
 O
 O
1eh8 1 P16455 100.0 5e-151 X-RAY
 2000-04-12 SER A:152 A:152 95.0 0.826 T -80.8 -14.8 95.0 0.826 0.0 HOH
 3.526
 OG
 O
1yfh 3 P16455 100.0 1e-130 X-RAY
 2005-12-13 SER E:152 A:152 99.0 0.861 T -55.8 -17.8 NA NA NA
SER F:152 B:152 91.0 0.791 T -91.5 35.7 NA NA NA
SER G:152 C:152 90.0 0.783 T -105.8 5.7 90.0 0.783 0.0 DG
DT
DG
DT
DC
DC
 7.101
4.685
6.167
8.681
8.053
8.732
 N
N
N
CB
O
OG
 O3'
OP2
OP2
C7
O5'
OP2
1t39 3 P16455 99.44 5e-129 X-RAY
 2004-07-13 SER E:164 A:152 104.0 0.904 T -61.3 -0.8 104.0 0.904 0.0 E1X
DC
DT
DA
DG
DT
DA
DC
DT
 9.896
6.856
4.443
5.479
8.324
8.251
8.994
9.067
9.417
 OG
N
N
N
CB
O
CB
CB
CB
 O3'
O3'
OP2
OP2
O6
C7
N6
N4
O4
SER F:164 B:152 119.0 1.0 T -56.3 -43.2 NA NA NA
1qnt 1 P16455 100.0 1e-128 X-RAY
 1999-12-16 SER A:152 A:152 101.0 0.878 T -77.6 -17.0 101.0 0.878 0.0 HOH
 2.660
 OG
 O
1t38 3 P16455 98.88 6e-128 X-RAY
 2004-07-13 SER C:164 A:152 104.0 0.904 T -67.5 4.1 104.0 0.904 0.0 DC
DT
DA
DG
DT
DC
 7.196
4.828
5.652
8.896
8.995
9.563
 N
N
N
CB
CB
CB
 O3'
OP2
OP2
O6
C7
N4
3kzy 1 ? 89.27 9e-112 X-RAY
 2010-12-15 ASP A:155 A:152 119.0 0.793 T -56.4 -36.4 119.0 0.793 0.0 HOH
 2.630
 OD2
 O
ASP B:155 B:152 115.0 0.767 T -56.5 -36.7 NA NA NA
3l00 1 ? 89.27 9e-112 X-RAY
 2010-12-15 ASP A:155 A:152 118.0 0.787 T -56.0 -36.7 118.0 0.787 0.0 HOH
 2.698
 OD2
 O
6sc2 2 E5BBQ0,B0I1S0 89.07 4e-111 EM
 2019-09-04 ASP B:152 NA:NA DO NA DO DO DO NA NA NA
6sc2 1 E5BBQ0,B0I1S0 89.07 4e-111 EM
 2019-09-04 ASP A:152 NA:NA DO NA DO DO DO NA NA NA
6rla 1 E5BBQ0,B0I1S0 89.07 4e-111 EM
 2019-08-28 ASP A:152 NA:NA DO NA DO DO DO NA NA NA
ASP B:152 NA:NA DO NA DO DO DO NA NA NA
6rlb 1 E5BBQ0,B0I1S0 89.07 4e-111 EM
 2019-08-28 ASP A:152 NA:NA DO NA DO DO DO NA NA NA
ASP B:152 NA:NA DO NA DO DO DO NA NA NA
3kzz 1 ? 88.7 7e-111 X-RAY
 2010-12-15 ASP A:155 A:152 119.0 0.793 T -54.1 -37.1 119.0 0.793 0.0 HOH
 2.685
 OD1
 O
6y8p 1 E5BBQ0 89.14 4e-110 X-RAY
 2021-03-31 ASP A:150 A:152 118.0 0.787 S -57.5 -31.8 118.0 0.787 0.0 HOH
 3.280
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16455-f1 1 P16455 100.0 2e-151 SER A:152 A:152 100.0 0.87 T -73.5 -6.7