Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr10 | 131565115 | . | G | A | CCDS7660.2:NM_002412.3:c.571Gga>Aga_NP_002403.2:p.191G>R | Homo sapiens O-6-methylguanine-DNA methyltransferase (MGMT), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1eh6 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLY | A:160 | A:160 | 36.0 | 0.48 | T | -86.3 | 14.8 | 36.0 | 0.48 | 0.0 |
HOH |
3.005 |
O |
O |
||
| 1eh7 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLY | A:160 | A:160 | 37.0 | 0.493 | T | -100.4 | 11.6 | 37.0 | 0.493 | 0.0 |
HOH |
2.624 |
O |
O |
||
| 1eh8 | 1 | P16455 | 100.0 | 5e-151 |
X-RAY |
2000-04-12 | GLY | A:160 | A:160 | 37.0 | 0.493 | T | -95.3 | 20.5 | 37.0 | 0.493 | 0.0 |
HOH |
5.159 |
CA |
O |
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| 1yfh | 3 | P16455 | 100.0 | 1e-130 |
X-RAY |
2005-12-13 | GLY | E:160 | A:160 | 44.0 | 0.587 | T | -62.3 | -0.1 | NA | NA | NA | ||||||
| GLY | F:160 | B:160 | 50.0 | 0.667 | S | -57.2 | 10.0 | NA | NA | NA | |||||||||||||
| GLY | G:160 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 1t39 | 3 | P16455 | 99.44 | 5e-129 |
X-RAY |
2004-07-13 | GLY | E:172 | A:160 | 31.0 | 0.413 | T | -82.4 | 46.7 | 31.0 | 0.413 | 0.0 |
E1X |
5.939 |
N |
O6 |
||
| GLY | F:172 | B:160 | 30.0 | 0.4 | T | -83.0 | 46.9 | NA | NA | NA | |||||||||||||
| 1qnt | 1 | P16455 | 100.0 | 1e-128 |
X-RAY |
1999-12-16 | GLY | A:160 | A:160 | 26.0 | 0.347 | T | -97.6 | 6.1 | 26.0 | 0.347 | 0.0 |
HOH |
2.829 |
O |
O |
||
| 1t38 | 3 | P16455 | 98.88 | 6e-128 |
X-RAY |
2004-07-13 | GLY | C:172 | A:160 | 43.0 | 0.573 | T | -66.1 | 25.7 | 43.0 | 0.573 | 0.0 |
6OG HOH |
4.999 7.733 |
N N |
O6 O |
||
| 3kzy | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | GLY | A:163 | A:160 | 44.0 | 0.587 | T | -83.4 | -3.4 | 44.0 | 0.587 | 0.0 |
HOH |
3.687 |
O |
O |
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| GLY | B:163 | B:160 | 40.0 | 0.533 | T | -85.5 | 12.1 | NA | NA | NA | |||||||||||||
| 3l00 | 1 | ? | 89.27 | 9e-112 |
X-RAY |
2010-12-15 | GLY | A:163 | A:160 | 37.0 | 0.493 | T | -95.6 | 9.7 | 37.0 | 0.493 | 0.0 |
HOH |
2.962 |
O |
O |
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| 6sc2 | 2 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | GLY | B:160 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6sc2 | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-09-04 | GLY | A:160 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6rla | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | GLY | A:160 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| GLY | B:160 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6rlb | 1 | E5BBQ0,B0I1S0 | 89.07 | 4e-111 |
EM |
2019-08-28 | GLY | A:160 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| GLY | B:160 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3kzz | 1 | ? | 88.7 | 7e-111 |
X-RAY |
2010-12-15 | GLY | A:163 | A:160 | 86.0 | 1.0 | T | 86.9 | 7.5 | 86.0 | 1.0 | 0.0 |
OBG HOH |
5.823 3.602 |
N C |
C6 O |
||
| 6y8p | 1 | E5BBQ0 | 89.14 | 4e-110 |
X-RAY |
2021-03-31 | GLY | A:158 | A:160 | 46.0 | 0.613 | T | -83.4 | -4.9 | 46.0 | 0.613 | 0.0 |
OGQ EDO HOH |
3.380 7.942 3.684 |
N CA CA |
CBC O2 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p16455-f1 | 1 | P16455 | 100.0 | 2e-151 | GLY | A:160 | A:160 | 16.0 | 0.213 | T | -75.9 | -5.0 | |