Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75830470 . G A CCDS7340.1:NM_003373.3:c.282atG>atA_NP_003364.1:p.94M>I Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
2020-09-30 MET A:94 NA:NA DO NA DO DO DO NA NA NA
MET C:94 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
2021-01-27 MET A:94 A:94 67.0 0.362 H -69.3 -23.0 67.0 0.362 0.0
7ktu 1 P18206 100.0 0.0 EM
2021-01-27 MET A:94 A:94 67.0 0.362 H -77.6 -29.5 67.0 0.362 0.0
7ktv 1 P18206 100.0 0.0 EM
2021-01-27 MET A:94 A:94 66.0 0.357 H -73.8 -23.2 66.0 0.357 0.0
7ktw 1 P18206 100.0 0.0 EM
2021-01-27 MET A:94 A:94 74.0 0.4 H -74.4 -30.5 74.0 0.4 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
2005-11-15 MSE A:94 A:94 50.0 0.27 H -67.1 -18.4 50.0 0.27 0.0
MSE B:94 B:94 53.0 0.286 H -62.1 -9.0 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
2018-03-14 MET A:94 A:94 74.0 0.4 H -69.6 -38.0 74.0 0.4 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
2020-01-29 MET A:114 A:94 81.0 0.438 H -61.6 -34.6 81.0 0.438 0.0
1st6 1 P12003 86.42 0.0 X-RAY
2004-08-03 MET A:97 A:94 63.0 0.341 H -78.7 -32.4 63.0 0.341 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
2006-08-08 MET A:94 A:94 49.0 0.265 H -59.5 -44.8 49.0 0.265 0.0 HOH
7.139
N
O
3rf3 1 P18206 100.0 0.0 X-RAY
2011-04-27 MET A:94 A:94 70.0 0.378 H -60.2 -44.8 70.0 0.378 0.0 HOH
2.782
O
O
MET B:94 B:94 64.0 0.346 H -62.0 -42.5 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
2012-02-29 MET A:94 A:94 54.0 0.292 H -69.7 -48.6 54.0 0.292 0.0 HOH
6.390
C
O
2gww 1 P18206 100.0 0.0 X-RAY
2006-11-14 MET A:102 A:94 52.0 0.281 H -67.3 -47.4 52.0 0.281 0.0 HOH
6.927
N
O
2hsq 1 P18206 100.0 0.0 X-RAY
2006-11-21 MET A:102 A:94 60.0 0.324 H -52.1 -28.6 60.0 0.324 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
2007-09-18 MET A:102 A:94 36.0 0.195 H -52.6 -35.4 36.0 0.195 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
2004-01-13 MET A:98 A:94 29.0 0.157 T -137.0 -4.0 29.0 0.157 0.0
1rke 1 P18206 100.0 0.0 X-RAY
2004-01-13 MET A:98 A:94 54.0 0.292 H -65.4 -39.4 54.0 0.292 0.0 HOH
5.601
C
O
1syq 1 P18206 100.0 0.0 X-RAY
2004-07-20 MET A:100 A:94 66.0 0.357 H -51.7 -46.4 66.0 0.357 0.0 HOH
4.665
N
O
1ydi 1 P18206-2 100.0 0.0 X-RAY
2005-07-19 MET A:99 A:94 47.0 0.254 H -68.7 -36.4 47.0 0.254 0.0 HOH
2.820
O
O
3tj6 1 P18206 100.0 0.0 X-RAY
2011-09-07 MET A:94 A:94 66.0 0.357 H -79.7 -16.1 66.0 0.357 0.0 HOH
3.350
CE
O
1u6h 1 P12003 98.07 4e-180 X-RAY
2005-01-18 MET A:115 A:93 48.0 0.259 H -60.0 -59.4 48.0 0.259 0.0 HOH
4.789
N
O
1xwj 1 P12003 98.07 4e-180 X-RAY
2005-10-11 MET A:115 A:93 47.0 0.254 H -53.8 -50.9 47.0 0.254 0.0 HOH
8.363
N
O
3zdl 1 P12003 98.07 4e-180 X-RAY
2013-02-13 MET A:115 A:93 49.0 0.265 H -59.6 -43.4 49.0 0.265 0.0 HOH
2.744
O
O
6fq4 1 P12003 98.07 4e-180 X-RAY
2018-05-09 MET A:115 A:94 55.0 0.297 H -62.6 -37.7 55.0 0.297 0.0
1zvz 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:114 A:93 42.0 0.227 H -61.7 -44.4 42.0 0.227 0.0 HOH
4.688
N
O
1zw2 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:114 A:93 48.0 0.259 H -58.6 -41.0 48.0 0.259 0.0 HOH
4.698
N
O
1zw3 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:114 A:93 50.0 0.27 H -60.9 -34.6 50.0 0.27 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
2012-05-16 MET A:98 A:94 45.0 0.243 H -60.2 -41.8 45.0 0.243 0.0 HOH
4.148
CG
O
4e18 1 P12003 98.07 7e-180 X-RAY
2012-05-16 MET A:98 A:94 48.0 0.259 H -62.8 -51.5 48.0 0.259 0.0 HOH
3.014
O
O
3tj5 1 P18206 100.0 9e-180 X-RAY
2011-09-07 MET A:94 A:94 50.0 0.27 H -65.9 -38.9 50.0 0.27 0.0 HOH
2.616
O
O
3s90 1 P18206 100.0 6e-177 X-RAY
2011-06-22 MET A:95 A:94 53.0 0.286 H -58.8 -39.2 53.0 0.286 0.0 HOH
3.923
CE
O
MET B:95 B:94 54.0 0.292 H -58.9 -38.5 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
2012-04-18 MET A:95 A:94 62.0 0.335 H -61.5 -40.6 62.0 0.335 0.0 ACT
HOH
9.146
2.984
O
O
OXT
O
1t01 1 P12003 98.03 3e-176 X-RAY
2004-08-24 MET A:95 A:94 47.0 0.254 H -56.0 -42.1 47.0 0.254 0.0 HOH
2.981
O
O
5y04 1 Q64727 100.0 3e-175 X-RAY
2018-03-28 MET A:96 A:94 75.0 0.405 H -60.2 -26.6 75.0 0.405 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 MET A:94 A:94 65.0 0.351 H -68.0 -41.7