Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75832560 . T A CCDS7340.1:NM_003373.3:c.572tTg>tAg_NP_003364.1:p.191L>* Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
 2020-09-30 LEU A:191 NA:NA DO NA DO DO DO NA NA NA
LEU C:191 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
 2021-01-27 LEU A:191 A:191 2.0 0.012 H -72.2 -61.9 2.0 0.012 0.0
7ktu 1 P18206 100.0 0.0 EM
 2021-01-27 LEU A:191 A:191 4.0 0.024 H -103.5 -57.1 4.0 0.024 0.0
7ktv 1 P18206 100.0 0.0 EM
 2021-01-27 LEU A:191 A:191 7.0 0.041 H -77.8 -55.0 7.0 0.041 0.0
7ktw 1 P18206 100.0 0.0 EM
 2021-01-27 LEU A:191 A:191 11.0 0.065 H -75.4 -46.3 11.0 0.065 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
 2005-11-15 LEU A:191 A:191 1.0 0.006 H -57.1 -45.3 1.0 0.006 0.0 HOH
 5.794
 N
 O
LEU B:191 B:191 2.0 0.012 H -63.1 -43.8 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
 2018-03-14 LEU A:191 A:191 0.0 0.0 H -63.0 -46.9 0.0 0.0 0.0 HOH
 4.721
 CD1
 O
6nr7 1 P12003 86.42 0.0 X-RAY
 2020-01-29 LEU A:211 A:191 0.0 0.0 H -55.0 -62.9 0.0 0.0 0.0 HOH
 8.450
 CD1
 O
1st6 1 P12003 86.42 0.0 X-RAY
 2004-08-03 LEU A:194 A:191 2.0 0.012 H -72.1 -42.8 2.0 0.012 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
 2006-08-08 LEU A:191 A:191 1.0 0.006 H -65.4 -53.6 1.0 0.006 0.0
3rf3 1 P18206 100.0 0.0 X-RAY
 2011-04-27 LEU A:191 A:191 0.0 0.0 H -67.5 -43.8 0.0 0.0 0.0 CAC
HOH
 8.604
4.377
 O
HD11
 O1
O
LEU B:191 B:191 0.0 0.0 H -67.1 -44.3 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
 2012-02-29 LEU A:191 A:191 0.0 0.0 H -66.5 -50.1 0.0 0.0 0.0 HOH
 4.696
 CD1
 O
2gww 1 P18206 100.0 0.0 X-RAY
 2006-11-14 LEU A:199 A:191 0.0 0.0 H -61.1 -51.9 0.0 0.0 0.0 HOH
 5.170
 O
 O
2hsq 1 P18206 100.0 0.0 X-RAY
 2006-11-21 LEU A:199 A:191 0.0 0.0 H -90.4 -38.4 0.0 0.0 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
 2007-09-18 LEU A:199 A:191 0.0 0.0 H -53.6 -49.5 0.0 0.0 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
 2004-01-13 LEU A:195 A:191 1.0 0.006 H -55.5 -51.2 1.0 0.006 0.0
1rke 1 P18206 100.0 0.0 X-RAY
 2004-01-13 LEU A:195 A:191 0.0 0.0 H -64.4 -49.0 0.0 0.0 0.0 HOH
 4.582
 N
 O
1syq 1 P18206 100.0 0.0 X-RAY
 2004-07-20 LEU A:197 A:191 0.0 0.0 H -59.9 -47.0 0.0 0.0 0.0 HOH
 5.073
 N
 O
1ydi 1 P18206-2 100.0 0.0 X-RAY
 2005-07-19 LEU A:196 A:191 0.0 0.0 H -63.9 -48.3 0.0 0.0 0.0 HOH
 3.709
 CA
 O
3tj6 1 P18206 100.0 0.0 X-RAY
 2011-09-07 LEU A:191 A:191 0.0 0.0 H -68.2 -43.7 0.0 0.0 0.0 HOH
 5.355
 N
 O
1u6h 1 P12003 98.07 4e-180 X-RAY
 2005-01-18 LEU A:212 A:190 1.0 0.006 H -50.3 -43.4 1.0 0.006 0.0 HOH
 4.383
 N
 O
1xwj 1 P12003 98.07 4e-180 X-RAY
 2005-10-11 LEU A:212 A:190 1.0 0.006 H -63.3 -51.7 1.0 0.006 0.0 HOH
 7.243
 N
 O
3zdl 1 P12003 98.07 4e-180 X-RAY
 2013-02-13 LEU A:212 A:190 0.0 0.0 H -66.8 -46.2 0.0 0.0 0.0 HOH
 4.695
 N
 O
6fq4 1 P12003 98.07 4e-180 X-RAY
 2018-05-09 LEU A:212 A:191 0.0 0.0 H -66.0 -63.8 0.0 0.0 0.0
1zvz 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 LEU A:211 A:190 0.0 0.0 H -66.2 -46.0 0.0 0.0 0.0 HOH
 4.602
 O
 O
1zw2 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 LEU A:211 A:190 0.0 0.0 H -64.9 -45.9 0.0 0.0 0.0 HOH
 4.984
 N
 O
1zw3 1 P12003 98.07 4e-180 X-RAY
 2005-09-20 LEU A:211 A:190 1.0 0.006 H -59.7 -52.5 1.0 0.006 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 LEU A:195 A:191 1.0 0.006 H -65.3 -47.8 1.0 0.006 0.0 HOH
 5.264
 CD1
 O
4e18 1 P12003 98.07 7e-180 X-RAY
 2012-05-16 LEU A:195 A:191 0.0 0.0 H -67.1 -43.0 0.0 0.0 0.0 HOH
 6.785
 CD1
 O
3tj5 1 P18206 100.0 9e-180 X-RAY
 2011-09-07 LEU A:191 A:191 0.0 0.0 H -66.4 -47.5 0.0 0.0 0.0 HOH
 5.038
 N
 O
3s90 1 P18206 100.0 6e-177 X-RAY
 2011-06-22 LEU A:192 A:191 0.0 0.0 H -64.2 -49.7 0.0 0.0 0.0 HOH
 4.692
 CD1
 O
LEU B:192 B:191 0.0 0.0 H -63.6 -49.4 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
 2012-04-18 LEU A:192 A:191 1.0 0.006 H -68.2 -47.8 1.0 0.006 0.0 HOH
 4.838
 N
 O
1t01 1 P12003 98.03 3e-176 X-RAY
 2004-08-24 LEU A:192 A:191 0.0 0.0 H -65.5 -41.9 0.0 0.0 0.0 HOH
 4.706
 N
 O
5y04 1 Q64727 100.0 3e-175 X-RAY
 2018-03-28 LEU A:193 A:191 0.0 0.0 H -64.9 -47.0 0.0 0.0 0.0 HOH
 8.504
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 LEU A:191 A:191 0.0 0.0 H -63.0 -47.2