Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr10 75834589 . G A CCDS7340.1:NM_003373.3:c.711atG>atA_NP_003364.1:p.237M>I Homo sapiens vinculin (VCL), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6upw 1 P18206 100.0 0.0 EM
2020-09-30 MET A:237 NA:NA DO NA DO DO DO NA NA NA
MET C:237 NA:NA DO NA DO DO DO NA NA NA
7ktt 1 P18206 100.0 0.0 EM
2021-01-27 MET A:237 A:237 3.0 0.016 H -61.6 -32.6 3.0 0.016 0.0
7ktu 1 P18206 100.0 0.0 EM
2021-01-27 MET A:237 A:237 12.0 0.065 H -67.0 -40.8 12.0 0.065 0.0
7ktv 1 P18206 100.0 0.0 EM
2021-01-27 MET A:237 A:237 11.0 0.059 H -72.7 -39.2 11.0 0.059 0.0
7ktw 1 P18206 100.0 0.0 EM
2021-01-27 MET A:237 A:237 5.0 0.027 H -69.0 -40.1 5.0 0.027 0.0
1tr2 1 P18206 90.83 0.0 X-RAY
2005-11-15 MSE A:237 A:237 2.0 0.011 H -55.8 -40.0 2.0 0.011 0.0 HOH
7.741
O
O
MSE B:237 B:237 1.0 0.005 H -61.9 -49.2 NA NA NA
6fuy 1 P18206 90.48 0.0 X-RAY
2018-03-14 MET A:237 A:237 0.0 0.0 H -62.2 -47.4 0.0 0.0 0.0
6nr7 1 P12003 86.42 0.0 X-RAY
2020-01-29 MET A:257 A:237 0.0 0.0 H -41.5 -47.6 0.0 0.0 0.0 HOH
7.478
O
O
1st6 1 P12003 86.42 0.0 X-RAY
2004-08-03 MET A:240 A:237 2.0 0.011 H -69.1 -48.9 2.0 0.011 0.0
2gdc 1 P12003 98.12 0.0 X-RAY
2006-08-08 MET A:237 A:237 0.0 0.0 H -66.6 -41.1 0.0 0.0 0.0 HOH
9.957
N
O
3rf3 1 P18206 100.0 0.0 X-RAY
2011-04-27 MET A:237 A:237 0.0 0.0 H -63.2 -44.2 0.0 0.0 0.0 HOH
4.904
N
O
MET B:237 B:237 0.0 0.0 H -62.2 -44.1 NA NA NA
4dj9 1 P18206 100.0 0.0 X-RAY
2012-02-29 MET A:237 A:237 0.0 0.0 H -67.9 -42.4 0.0 0.0 0.0 HOH
5.923
C
O
2gww 1 P18206 100.0 0.0 X-RAY
2006-11-14 MET A:245 A:237 0.0 0.0 H -59.9 -50.5 0.0 0.0 0.0 HOH
4.824
CE
O
2hsq 1 P18206 100.0 0.0 X-RAY
2006-11-21 MET A:245 A:237 0.0 0.0 H -65.7 -49.3 0.0 0.0 0.0
2ibf 1 P18206 100.0 0.0 X-RAY
2007-09-18 MET A:245 A:237 0.0 0.0 H -58.9 -43.7 0.0 0.0 0.0
1rkc 1 P18206 100.0 0.0 X-RAY
2004-01-13 MET A:241 A:237 0.0 0.0 H -63.3 -29.9 0.0 0.0 0.0
1rke 1 P18206 100.0 0.0 X-RAY
2004-01-13 MET A:241 A:237 0.0 0.0 H -62.6 -49.6 0.0 0.0 0.0 HOH
4.654
N
O
1syq 1 P18206 100.0 0.0 X-RAY
2004-07-20 MET A:243 A:237 0.0 0.0 H -68.7 -42.6 0.0 0.0 0.0 HOH
6.024
C
O
1ydi 1 P18206-2 100.0 0.0 X-RAY
2005-07-19 MET A:242 A:237 0.0 0.0 H -67.8 -40.1 0.0 0.0 0.0 HOH
4.779
N
O
3tj6 1 P18206 100.0 0.0 X-RAY
2011-09-07 MET A:237 A:237 0.0 0.0 H -60.0 -42.6 0.0 0.0 0.0 HOH
6.175
C
O
1u6h 1 P12003 98.07 4e-180 X-RAY
2005-01-18 MET A:258 A:236 0.0 0.0 H -68.3 -48.2 0.0 0.0 0.0 HOH
6.961
O
O
1xwj 1 P12003 98.07 4e-180 X-RAY
2005-10-11 MET A:258 A:236 0.0 0.0 H -71.7 -36.5 0.0 0.0 0.0 HOH
6.652
C
O
3zdl 1 P12003 98.07 4e-180 X-RAY
2013-02-13 MET A:258 A:236 0.0 0.0 H -57.2 -42.8 0.0 0.0 0.0 HOH
6.867
C
O
6fq4 1 P12003 98.07 4e-180 X-RAY
2018-05-09 MET A:258 A:237 1.0 0.005 H -58.6 -50.7 1.0 0.005 0.0
1zvz 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:257 A:236 0.0 0.0 H -61.6 -44.3 0.0 0.0 0.0 HOH
5.783
N
O
1zw2 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:257 A:236 0.0 0.0 H -66.9 -45.9 0.0 0.0 0.0 HOH
5.947
C
O
1zw3 1 P12003 98.07 4e-180 X-RAY
2005-09-20 MET A:257 A:236 0.0 0.0 H -58.2 -61.7 0.0 0.0 0.0
4e17 1 P12003 98.07 7e-180 X-RAY
2012-05-16 MET A:241 A:237 0.0 0.0 H -64.0 -40.5 0.0 0.0 0.0 HOH
6.675
C
O
4e18 1 P12003 98.07 7e-180 X-RAY
2012-05-16 MET A:241 A:237 0.0 0.0 H -66.8 -43.3 0.0 0.0 0.0 HOH
6.694
C
O
3tj5 1 P18206 100.0 9e-180 X-RAY
2011-09-07 MET A:237 A:237 0.0 0.0 H -62.7 -41.4 0.0 0.0 0.0 HOH
6.457
C
O
3s90 1 P18206 100.0 6e-177 X-RAY
2011-06-22 MET A:238 A:237 0.0 0.0 H -62.9 -42.7 0.0 0.0 0.0 HOH
4.653
N
O
MET B:238 B:237 0.0 0.0 H -63.3 -42.0 NA NA NA
4ehp 1 P18206 100.0 6e-177 X-RAY
2012-04-18 MET A:238 A:237 0.0 0.0 H -63.4 -40.6 0.0 0.0 0.0 HOH
6.845
C
O
1t01 1 P12003 98.03 3e-176 X-RAY
2004-08-24 MET A:238 A:237 0.0 0.0 H -68.2 -49.4 0.0 0.0 0.0 HOH
6.083
C
O
5y04 1 Q64727 100.0 3e-175 X-RAY
2018-03-28 MET A:239 A:237 0.0 0.0 H -60.2 -37.9 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18206-f1 1 P18206 100.0 0.0 MET A:237 A:237 0.0 0.0 H -57.7 -41.5