Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 112014514 . C A CCDS44731.1:NM_001562.3:c.387aaG>aaT_NP_001553.1:p.129K>N Homo sapiens interleukin 18 (IL18), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wo2 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 LYS A:93 A:93 204.0 1.0 -73.4 -35.7 204.0 1.0 0.0 HOH
 2.843
 N
 O
LYS B:93 B:93 202.0 1.0 -74.0 -36.0 NA NA NA
LYS C:93 C:93 203.0 1.0 -72.8 -36.6 NA NA NA
LYS D:93 D:93 160.0 0.8 -74.0 -36.6 NA NA NA
3wo3 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 LYS A:93 A:93 115.0 NA -96.2 51.2 71.0 NA NA B:Q13478:NA
 SO4
SO4
HOH
 7.437
8.064
8.509
 CG
CG
CG
 O2
O2
O
LYS C:93 C:93 175.0 0.875 -94.0 48.2 NA NA NA
LYS E:93 E:93 174.0 0.87 -95.1 47.6 NA NA NA
LYS G:93 G:93 174.0 0.87 -95.3 48.7 NA NA NA
LYS I:93 I:93 102.0 NA -95.0 50.0 NA NA NA
LYS K:93 K:93 80.0 NA -62.2 158.2 NA NA NA
3wo4 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 LYS A:93 A:93 177.0 0.885 -88.4 64.3 140.0 0.7 0.185 B:Q13478:0.185
 HOH
 6.209
 O
 O
4xft 1 Q14116 97.45 3e-111 X-RAY
 2015-06-10 LYS A:93 A:93 168.0 0.84 -80.2 -17.7 168.0 0.84 0.0 HOH
 2.750
 O
 O
LYS B:93 B:93 198.0 0.99 -82.1 -17.6 NA NA NA
2vxt 2 Q14116 97.45 4e-111 X-RAY
 2009-06-23 LYS B:93 I:129 175.0 0.875 S -71.6 -24.5 175.0 0.875 0.0 HOH
 3.006
 O
 O
4hjj 1 Q14116 97.44 1e-110 X-RAY
 2013-05-08 LYS A:93 A:129 180.0 0.9 -65.2 -59.9 180.0 0.9 0.0 HOH
 3.413
 O
 O
4xfs 1 Q14116 96.82 1e-110 X-RAY
 2015-06-10 LYS A:93 A:93 145.0 0.725 -72.7 -31.2 145.0 0.725 0.0 HOH
 2.619
 O
 O
LYS B:93 B:93 143.0 0.715 -72.6 -31.3 NA NA NA
4r6u 2 Q14116 97.45 2e-110 X-RAY
 2014-10-15 LYS C:93 B:93 166.0 0.83 -91.9 28.7 152.0 0.76 0.07 A:Q13478:0.07
LYS D:93 D:93 167.0 0.835 -95.1 24.1 NA NA NA
3f62 2 Q14116 97.45 2e-110 X-RAY
 2009-01-06 LYS B:94 B:93 183.0 0.915 -79.5 -14.0 183.0 0.915 0.0 HOH
 3.070
 N
 O
4xfu 1 Q14116 96.18 3e-109 X-RAY
 2015-06-10 LYS A:93 A:93 169.0 0.845 -100.3 52.6 169.0 0.845 0.0
LYS B:93 B:93 165.0 0.825 -98.7 55.8 NA NA NA
4eee 2 Q14116 94.9 2e-101 X-RAY
 2012-09-26 LYS B:93 B:93 180.0 0.9 -90.5 61.9 180.0 0.9 0.0 HOH
 9.366
 O
 O
LYS D:93 D:93 164.0 0.82 -89.7 62.1 164.0 0.82 0.0 HOH
 4.175
 NZ
 O
4ekx 2 Q14116 94.9 2e-101 X-RAY
 2012-09-26 LYS B:93 B:93 160.0 0.8 S -93.8 73.6 160.0 0.8 0.0 HOH
 2.866
 N
 O
LYS C:93 D:93 165.0 0.825 S -93.2 74.7 165.0 0.825 0.0 HOH
 2.813
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14116-f1 1 Q14116 100.0 2e-142 LYS A:129 A:129 132.0 0.66 -78.3 -27.2