Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 112020809 . T A CCDS44731.1:NM_001562.3:c.212gAt>gTt_NP_001553.1:p.71D>V Homo sapiens interleukin 18 (IL18), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wo2 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 ASP A:35 A:35 127.0 0.847 H -62.1 -26.0 127.0 0.847 0.0 CPS
HOH
 3.508
3.177
 O
OD2
 C13
O
ASP B:35 B:35 130.0 0.867 H -62.4 -34.5 NA NA NA
ASP C:35 C:35 135.0 0.9 H -61.3 -37.1 NA NA NA
ASP D:35 D:35 84.0 NA H -60.4 -36.8 NA NA NA
3wo3 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 ASP A:35 A:35 112.0 0.747 H -43.2 -47.8 26.0 0.173 0.574 B:Q13478:0.573
 NAG
NAG
SO4
HOH
 4.010
8.537
3.187
6.913
 OD2
OD2
O
O
 O7
C1
O2
O
ASP C:35 C:35 106.0 0.707 H -51.1 -46.6 NA NA NA
ASP E:35 E:35 111.0 0.74 H -50.1 -47.3 NA NA NA
ASP G:35 G:35 112.0 0.747 H -51.6 -46.1 NA NA NA
ASP I:35 I:35 109.0 0.727 H -51.2 -46.2 NA NA NA
ASP K:35 K:35 113.0 0.753 H -50.6 -47.6 NA NA NA
3wo4 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 ASP A:35 A:35 111.0 0.74 H -47.9 -42.3 25.0 0.167 0.573 B:Q13478:0.573
 NAG
NAG
HOH
 4.203
9.465
4.959
 OD2
OD2
OD1
 O7
C1
O
4xft 1 Q14116 97.45 3e-111 X-RAY
 2015-06-10 ASP A:35 A:35 87.0 0.58 H -48.3 -33.3 87.0 0.58 0.0 HOH
 5.045
 OD1
 O
ASP B:35 B:35 90.0 0.6 H -58.6 -29.8 NA NA NA
2vxt 2 Q14116 97.45 4e-111 X-RAY
 2009-06-23 ASP B:35 I:71 76.0 0.507 H -59.1 -34.2 76.0 0.507 0.0 HOH
 3.645
 N
 O
4hjj 1 Q14116 97.44 1e-110 X-RAY
 2013-05-08 ASP A:35 A:71 39.0 0.26 H -61.7 -36.3 39.0 0.26 0.0 HOH
 2.995
 N
 O
4xfs 1 Q14116 96.82 1e-110 X-RAY
 2015-06-10 ASP A:35 A:35 119.0 0.793 H -53.9 -40.3 119.0 0.793 0.0 HOH
 2.891
 OD1
 O
ASP B:35 B:35 117.0 0.78 H -54.8 -39.9 NA NA NA
4r6u 2 Q14116 97.45 2e-110 X-RAY
 2014-10-15 ASP C:35 B:35 107.0 0.713 H -65.7 -30.4 28.0 0.187 0.526 A:Q13478:0.527
 NAG
 4.209
 OD2
 O7
ASP D:35 D:35 102.0 0.68 H -66.5 -34.9 NA NA NA
3f62 2 Q14116 97.45 2e-110 X-RAY
 2009-01-06 ASP B:36 NA:NA DO NA DO DO DO NA NA NA
4xfu 1 Q14116 96.18 3e-109 X-RAY
 2015-06-10 ASP A:35 NA:NA DO NA DO DO DO NA NA NA
ASP B:35 B:35 180.0 1.0 -178.5 360.0 NA NA NA
4eee 2 Q14116 94.9 2e-101 X-RAY
 2012-09-26 ASP B:35 NA:NA DO NA DO DO DO NA NA NA
ASP D:35 NA:NA DO NA DO DO DO NA NA NA
4ekx 2 Q14116 94.9 2e-101 X-RAY
 2012-09-26 ASP B:35 NA:NA DO NA DO DO DO NA NA NA
ASP C:35 D:35 110.0 0.733 G -107.5 8.9 110.0 0.733 0.0 HOH
 4.258
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14116-f1 1 Q14116 100.0 2e-142 ASP A:71 A:71 99.0 0.66 H -63.4 -21.7