Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 112020882 | . | C | A | CCDS44731.1:NM_001562.3:c.139Gtc>Ttc_NP_001553.1:p.47V>F | Homo sapiens interleukin 18 (IL18), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3wo2 | 1 | Q14116 | 100.0 | 4e-114 |
X-RAY |
2014-12-17 | VAL | A:11 | A:11 | 18.0 | 0.116 | E | -110.4 | 132.6 | 18.0 | 0.116 | 0.0 |
CPS CPS HOH |
9.521 3.874 3.593 |
CG2 CG2 CA |
C16 C18 O |
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VAL | B:11 | B:11 | 20.0 | 0.129 | E | -112.4 | 128.7 | NA | NA | NA | |||||||||||||
VAL | C:11 | C:11 | 18.0 | 0.116 | E | -112.3 | 132.1 | NA | NA | NA | |||||||||||||
VAL | D:11 | D:11 | 18.0 | 0.116 | E | -111.3 | 131.3 | NA | NA | NA | |||||||||||||
3wo3 | 1 | Q14116 | 100.0 | 4e-114 |
X-RAY |
2014-12-17 | VAL | A:11 | A:11 | 8.0 | 0.052 | E | -108.5 | 111.6 | 8.0 | 0.052 | 0.0 |
SO4 HOH |
4.079 4.268 |
CG2 CG2 |
O3 O |
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VAL | C:11 | C:11 | 0.0 | 0.0 | E | -118.5 | 110.0 | NA | NA | NA | |||||||||||||
VAL | E:11 | E:11 | 1.0 | 0.006 | E | -117.3 | 111.7 | NA | NA | NA | |||||||||||||
VAL | G:11 | G:11 | 1.0 | 0.006 | E | -110.7 | 110.5 | NA | NA | NA | |||||||||||||
VAL | I:11 | I:11 | 5.0 | 0.032 | E | -109.6 | 112.5 | NA | NA | NA | |||||||||||||
VAL | K:11 | K:11 | 0.0 | 0.0 | E | -114.2 | 110.0 | NA | NA | NA | |||||||||||||
3wo4 | 1 | Q14116 | 100.0 | 4e-114 |
X-RAY |
2014-12-17 | VAL | A:11 | A:11 | 3.0 | 0.019 | E | -114.6 | 114.3 | 3.0 | 0.019 | 0.0 |
HOH |
5.112 |
CG1 |
O |
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4xft | 1 | Q14116 | 97.45 | 3e-111 |
X-RAY |
2015-06-10 | VAL | A:11 | A:11 | 9.0 | 0.058 | E | -117.0 | 132.4 | 9.0 | 0.058 | 0.0 |
HOH |
3.463 |
CA |
O |
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VAL | B:11 | B:11 | 1.0 | 0.006 | E | -117.3 | 134.2 | NA | NA | NA | |||||||||||||
2vxt | 2 | Q14116 | 97.45 | 4e-111 |
X-RAY |
2009-06-23 | VAL | B:11 | I:47 | 5.0 | 0.032 | E | -103.3 | 132.8 | 5.0 | 0.032 | 0.0 |
HOH |
3.532 |
CA |
O |
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4hjj | 1 | Q14116 | 97.44 | 1e-110 |
X-RAY |
2013-05-08 | VAL | A:11 | A:47 | 0.0 | 0.0 | E | -105.3 | 118.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.582 |
O |
O |
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4xfs | 1 | Q14116 | 96.82 | 1e-110 |
X-RAY |
2015-06-10 | VAL | A:11 | A:11 | 8.0 | 0.052 | E | -99.6 | 141.0 | 8.0 | 0.052 | 0.0 |
DMS DMS HOH |
8.153 8.675 3.426 |
O N CG1 |
C1 O O |
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VAL | B:11 | B:11 | 1.0 | 0.006 | E | -100.4 | 140.9 | NA | NA | NA | |||||||||||||
4r6u | 2 | Q14116 | 97.45 | 2e-110 |
X-RAY |
2014-10-15 | VAL | C:11 | B:11 | 11.0 | 0.071 | E | -116.7 | 112.2 | 11.0 | 0.071 | 0.0 | ||||||
VAL | D:11 | D:11 | 8.0 | 0.052 | E | -116.8 | 113.1 | NA | NA | NA | |||||||||||||
3f62 | 2 | Q14116 | 97.45 | 2e-110 |
X-RAY |
2009-01-06 | VAL | B:12 | B:11 | 10.0 | 0.065 | E | -103.5 | 132.4 | 10.0 | 0.065 | 0.0 |
HOH |
3.663 |
CA |
O |
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4xfu | 1 | Q14116 | 96.18 | 3e-109 |
X-RAY |
2015-06-10 | VAL | A:11 | A:11 | 33.0 | 0.213 | E | -117.2 | 115.2 | 33.0 | 0.213 | 0.0 | ||||||
VAL | B:11 | B:11 | 21.0 | 0.135 | -117.3 | 114.6 | NA | NA | NA | ||||||||||||||
4eee | 2 | Q14116 | 94.9 | 2e-101 |
X-RAY |
2012-09-26 | VAL | B:11 | B:11 | 22.0 | 0.142 | E | -111.0 | 128.2 | 22.0 | 0.142 | 0.0 |
HOH |
8.379 |
CG1 |
O |
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VAL | D:11 | D:11 | 28.0 | 0.181 | E | -111.5 | 127.8 | 28.0 | 0.181 | 0.0 | |||||||||||||
4ekx | 2 | Q14116 | 94.9 | 2e-101 |
X-RAY |
2012-09-26 | VAL | B:11 | B:11 | 27.0 | 0.174 | E | -108.7 | 126.4 | 27.0 | 0.174 | 0.0 |
HOH |
3.427 |
CA |
O |
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VAL | C:11 | D:11 | 10.0 | 0.065 | E | -119.5 | 140.4 | 10.0 | 0.065 | 0.0 |
HOH |
3.460 |
CG1 |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q14116-f1 | 1 | Q14116 | 100.0 | 2e-142 | VAL | A:47 | A:47 | 4.0 | 0.026 | E | -98.8 | 131.5 |