Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706664 . C A CCDS8378.1:NM_000039.1:c.664Gag>Tag_NP_000030.1:p.222E>* Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 GLU A:198 A:198 83.0 0.437 H -75.3 -32.5 67.0 0.353 0.084 B:P02647:0.084
 POV
CLR
POV
POV
 7.287
8.236
9.726
7.792
 OE1
O
OE2
O
 C35
C21
C316
C215
GLU B:198 B:198 87.0 0.458 H -69.7 -65.7 40.0 0.211 0.247 A:P02647:0.247
 POV
POV
POV
POV
 7.435
6.995
9.326
7.578
 OE2
O
N
N
 C211
C1
C211
C22
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 GLU A:156 A:198 123.0 0.647 H -52.9 -43.9 123.0 0.647 0.0
GLU B:156 B:198 138.0 0.726 H -82.4 -43.6 138.0 0.726 0.0
GLU C:156 C:198 123.0 0.647 H -52.8 -43.9 123.0 0.647 0.0
GLU D:156 D:198 139.0 0.732 H -82.4 -43.6 139.0 0.732 0.0
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 GLU E:155 A0:198 106.0 0.558 H -75.3 -8.3 88.0 0.463 0.095 F:P02647:0.095
 PEV
PEV
PEV
PEV
PEV
PGV
PEV
 7.157
3.369
8.635
5.679
9.800
4.163
6.464
 OE1
OE1
OE2
OE1
OE2
CG
OE2
 C48
C33
C48
C47
C26
C5
C48
GLU F:155 A1:198 128.0 0.674 H -63.6 -44.4 42.0 0.221 0.453 DA:Q0TA84:0.379
E:P02647:0.089
 PGV
 5.897
 OE1
 C18
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLU A:155 A:355 130.0 0.684 H -68.9 -29.0 120.0 0.632 0.052 B:P02647:0.053
 PCW
 9.250
 H
 C21
GLU B:155 C:553 91.0 0.479 H -61.2 -44.0 67.0 0.353 0.126 A:P02647:0.126
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLU A:155 A:355 118.0 0.621 H -68.0 -39.9 108.0 0.568 0.053 B:P02647:0.053
 PCW
 7.764
 H
 C21
GLU B:155 C:553 107.0 0.563 H -64.2 -32.9 76.0 0.4 0.163 A:P02647:0.163
 PCW
 9.824
 O
 C26
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLU A:157 A:355 120.0 0.632 H -68.1 -30.0 101.0 0.532 0.1 B:P02647:0.1
 PCW
 7.650
 C
 C21
GLU B:157 C:553 115.0 0.605 H -63.3 -43.2 89.0 0.468 0.137 A:P02647:0.137
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLU A:157 A:355 115.0 0.605 H -67.7 -36.1 95.0 0.5 0.105 B:P02647:0.105
 PCW
 7.254
 C
 C20
GLU B:157 C:553 98.0 0.516 H -67.0 -39.1 68.0 0.358 0.158 A:P02647:0.158
 PCW
 9.804
 C
 C28
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLU A:157 A:355 128.0 0.674 H -63.2 -40.0 98.0 0.516 0.158 B:P02647:0.158
 PCW
 7.446
 N
 C19
GLU B:157 C:553 108.0 0.568 H -63.4 -41.1 82.0 0.432 0.136 A:P02647:0.137
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLU A:157 A:355 123.0 0.647 H -63.3 -38.5 106.0 0.558 0.089 C:P02647:0.089
 PCW
 8.366
 N
 C27
GLU C:157 C:553 118.0 0.621 H -64.4 -29.5 109.0 0.574 0.047 A:P02647:0.047
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 GLU A:157 A:355 128.0 0.674 H -63.2 -40.0 98.0 0.516 0.158 C:P02647:0.158
GLU C:157 C:553 108.0 0.568 H -63.5 -41.0 82.0 0.432 0.136 A:P02647:0.137
 PCW
PCW
 9.171
8.692
 O
N
 C28
C28
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLU A:157 A:355 128.0 0.674 H -66.8 -30.2 90.0 0.474 0.2 C:P02647:0.2
GLU C:157 C:553 118.0 0.621 H -65.5 -27.6 82.0 0.432 0.189 A:P02647:0.189
 PCW
 9.786
 N
 C28
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 GLU A:157 A:355 123.0 0.647 H -67.1 -41.8 118.0 0.621 0.026 B:P02647:0.026
 PCW
 9.785
 H
 C20
GLU B:157 D:553 107.0 0.563 H -61.1 -52.4 77.0 0.405 0.158 A:P02647:0.158
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 GLU A:157 A:355 122.0 0.642 H -63.2 -37.3 115.0 0.605 0.037 B:P02647:0.037
 PCW
 8.379
 C
 C20
GLU B:157 D:553 109.0 0.574 H -63.7 -29.9 88.0 0.463 0.111 A:P02647:0.111
 PCW
 9.881
 O
 C26
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLU C:157 D:398 148.0 0.779 H -63.8 -33.6 142.0 0.747 0.032 D:P02647:0.032
 7Q9
7Q9
 5.994
6.877
 N
N
 O32
C39
GLU D:157 E:698 131.0 0.689 H -70.5 -33.6 127.0 0.668 0.021 C:P02647:0.021
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLU C:157 D:398 146.0 0.768 H -67.1 -35.1 143.0 0.753 0.015 D:P02647:0.016
 7Q9
7Q9
 6.564
8.131
 H
N
 C316
C39
GLU D:157 E:698 122.0 0.642 H -63.2 -33.2 119.0 0.626 0.016 C:P02647:0.016
 7Q9
 9.882
 C
 C316
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 GLU C:165 NA:NA DO NA DO DO DO NA NA NA
GLU D:165 NA:NA DO NA DO DO DO NA NA NA
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLU B:166 B:220 98.0 0.516 H -61.7 -43.9 94.0 0.495 0.021 C:P02647:0.021
 PX4
PX4
PX4
 6.366
6.268
4.756
 H
C
O
 H40
H42
H71
GLU C:166 C:220 120.0 0.632 H -57.5 -48.3 92.0 0.484 0.148 B:P02647:0.147
 PX4
PX4
PX4
PX4
 6.805
6.445
6.877
9.756
 C
O
N
HB2
 H53
H64
H53
H72
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLU B:166 B:220 132.0 0.695 H -58.7 -45.1 125.0 0.658 0.037 C:P02647:0.037
 PX4
PX4
PX4
 7.134
6.775
6.990
 N
O
C
 H61
H5
H41
GLU C:166 C:220 117.0 0.616 H -62.3 -41.6 94.0 0.495 0.121 B:P02647:0.121
 PX4
PX4
PX4
PX4
PX4
 6.515
5.782
5.467
6.700
7.839
 HB3
O
HB3
O
H
 H53
H45
H41
H3
H49
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 GLU A:122 A:198 114.0 0.6 H -70.9 -36.1 114.0 0.6 0.0
GLU B:122 B:198 123.0 0.647 H -70.9 -36.1 123.0 0.647 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 GLU A:222 A:222 137.0 0.721 H -63.1 -41.4