Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706733 . C A CCDS8378.1:NM_000039.1:c.595Gcc>Tcc_NP_000030.1:p.199A>S Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 ALA A:175 A:175 57.0 0.496 H -43.0 -30.2 47.0 0.409 0.087 B:P02647:0.087
 POV
POV
POV
 6.042
9.493
7.559
 N
N
O
 C24
C29
C313
ALA B:175 B:175 68.0 0.591 S -81.7 155.1 61.0 0.53 0.061 A:P02647:0.061
 POV
POV
POV
POV
POV
 9.369
9.905
5.686
7.434
8.158
 O
O
O
N
N
 C217
C216
C38
C34
O14
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 ALA A:133 A:175 63.0 0.548 H -56.4 -56.5 41.0 0.357 0.191 D:P02647:0.191
ALA B:133 B:175 43.0 0.374 H -54.7 -62.1 36.0 0.313 0.061 C:P02647:0.061
ALA C:133 C:175 65.0 0.565 H -56.4 -56.6 41.0 0.357 0.208 B:P02647:0.209
ALA D:133 D:175 44.0 0.383 H -54.6 -62.1 38.0 0.33 0.053 A:P02647:0.052
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 ALA E:132 A0:175 67.0 0.583 G -92.6 11.5 67.0 0.583 0.0 PGV
PEV
PGV
PGV
PEV
PEV
 3.226
6.453
7.834
6.969
4.155
8.044
 O
CB
O
O
C
C
 O06
N6
C11
C31
C26
C26
ALA F:132 A1:175 63.0 0.548 H 74.0 40.4 63.0 0.548 0.0 PEV
PEV
 4.671
7.025
 CB
N
 N6
C19
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 ALA A:132 A:332 39.0 0.339 H -57.4 -50.0 39.0 0.339 0.0
ALA B:132 C:530 54.0 0.47 H -65.6 -43.0 54.0 0.47 0.0
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 ALA A:132 A:332 39.0 0.339 H -63.7 -44.7 39.0 0.339 0.0
ALA B:132 C:530 54.0 0.47 H -65.2 -43.7 54.0 0.47 0.0
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:134 A:332 40.0 0.348 H -65.6 -43.8 40.0 0.348 0.0
ALA B:134 C:530 41.0 0.357 H -66.6 -46.6 41.0 0.357 0.0
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:134 A:332 44.0 0.383 H -60.7 -47.0 44.0 0.383 0.0
ALA B:134 C:530 55.0 0.478 H -62.5 -44.7 55.0 0.478 0.0
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:134 A:332 39.0 0.339 H -63.9 -43.1 39.0 0.339 0.0
ALA B:134 C:530 46.0 0.4 H -63.1 -47.9 46.0 0.4 0.0
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 ALA A:134 A:332 51.0 0.443 H -60.6 -45.3 51.0 0.443 0.0
ALA C:134 C:530 41.0 0.357 H -59.2 -49.6 41.0 0.357 0.0
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 ALA A:134 A:332 39.0 0.339 H -64.0 -43.1 39.0 0.339 0.0
ALA C:134 C:530 47.0 0.409 H -63.1 -47.8 47.0 0.409 0.0
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 ALA A:134 A:332 33.0 0.287 H -62.9 -43.8 33.0 0.287 0.0
ALA C:134 C:530 42.0 0.365 H -62.7 -47.7 42.0 0.365 0.0
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 ALA A:134 A:332 51.0 0.443 H -60.2 -46.3 51.0 0.443 0.0
ALA B:134 D:530 52.0 0.452 H -63.6 -37.6 52.0 0.452 0.0
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 ALA A:134 A:332 44.0 0.383 H -62.7 -42.9 44.0 0.383 0.0
ALA B:134 D:530 58.0 0.504 H -60.9 -46.2 58.0 0.504 0.0
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 ALA C:134 D:375 57.0 0.496 H -55.5 -44.5 57.0 0.496 0.0 7Q9
7Q9
7Q9
7Q9
 3.780
9.481
9.968
7.439
 CB
H
H
H
 C35
C311
C318
C318
ALA D:134 E:675 54.0 0.47 H -62.2 -43.6 54.0 0.47 0.0 17F
7Q9
7Q9
 6.759
8.942
9.646
 CA
H
O
 O8
C22
C32
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 ALA C:134 D:375 53.0 0.461 H -57.8 -48.2 53.0 0.461 0.0 7Q9
7Q9
 3.155
8.921
 CB
O
 C35
O32
ALA D:134 E:675 60.0 0.522 H -63.6 -44.5 60.0 0.522 0.0 17F
7Q9
 5.951
8.501
 CB
O
 O8
C32
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 ALA C:142 NA:NA DO NA DO DO DO NA NA NA
ALA D:142 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 ALA A:176 A:175 43.0 0.374 H -49.6 -42.6 0.0 0.0 0.374 A:P02647:0.374
 HOH
 9.440
 CB
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 ALA B:143 B:197 40.0 0.348 H -62.3 -41.4 40.0 0.348 0.0 PX4
PX4
PX4
PX4
PX4
 6.909
2.303
5.517
8.819
7.541
 HB1
HA
HA
N
HA
 O6
H46
H37
H38
H71
ALA C:143 C:197 53.0 0.461 H -65.9 -35.9 53.0 0.461 0.0 PX4
PX4
PX4
PX4
PX4
 6.029
9.099
5.477
8.189
9.795
 C
H
N
N
N
 H70
H61
H69
H51
H61
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 ALA B:143 B:197 45.0 0.391 H -54.6 -41.7 45.0 0.391 0.0 PX4
PX4
PX4
PX4
PX4
PX4
PX4
 8.424
2.726
9.675
6.215
6.499
9.603
6.834
 HB2
HB2
O
O
N
H
HA
 H18
H46
H9
H68
H31
H54
H39
ALA C:143 C:197 66.0 0.574 H -73.0 -18.6 66.0 0.574 0.0 PX4
PX4
PX4
PX4
 9.884
9.506
7.948
7.438
 N
HB2
N
HA
 H72
O2
H10
O1
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 ALA A:99 A:175 39.0 0.339 H -54.9 -34.3 30.0 0.261 0.078 B:P02647:0.078
ALA B:99 B:175 39.0 0.339 H -55.1 -34.3 30.0 0.261 0.078 A:P02647:0.078

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 ALA A:199 A:199 53.0 0.461 H -59.9 -49.6