Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706766 . C A CCDS8378.1:NM_000039.1:c.562Gcc>Tcc_NP_000030.1:p.188A>S Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 ALA A:164 A:164 49.0 0.426 S -146.8 147.5 49.0 0.426 0.0 POV
 8.652
 O
 C15
ALA B:164 B:164 48.0 0.417 S -151.0 146.6 48.0 0.417 0.0 POV
POV
 5.781
6.419
 O
O
 O13
O22
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 ALA A:122 A:164 49.0 0.426 H -19.1 -48.9 49.0 0.426 0.0
ALA B:122 B:164 41.0 0.357 H -29.0 -49.7 41.0 0.357 0.0
ALA C:122 C:164 49.0 0.426 H -19.1 -48.9 49.0 0.426 0.0
ALA D:122 D:164 38.0 0.33 H -29.1 -49.7 38.0 0.33 0.0
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 ALA E:121 A0:164 24.0 0.209 H -67.7 -42.1 24.0 0.209 0.0 PEV
PEV
 5.645
7.084
 O
C
 C37
C42
ALA F:121 A1:164 51.0 0.443 167.8 87.4 51.0 0.443 0.0 PEV
PEV
 3.398
7.290
 O
N
 C13
C40
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 ALA A:121 A:321 56.0 0.487 H -56.1 -60.9 56.0 0.487 0.0 PCW
 8.780
 N
 C21
ALA B:121 C:519 52.0 0.452 H -48.5 -59.0 52.0 0.452 0.0
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 ALA A:121 A:321 61.0 0.53 H -50.8 -58.1 61.0 0.53 0.0
ALA B:121 C:519 54.0 0.47 H -48.4 -59.4 54.0 0.47 0.0
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:123 A:321 55.0 0.478 H -57.4 -59.9 55.0 0.478 0.0 PCW
 8.520
 N
 C15
ALA B:123 C:519 55.0 0.478 H -56.6 -55.0 55.0 0.478 0.0
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:123 A:321 54.0 0.47 H -56.9 -60.2 54.0 0.47 0.0 PCW
 8.427
 N
 C20
ALA B:123 C:519 57.0 0.496 H -56.6 -59.4 57.0 0.496 0.0
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:123 A:321 59.0 0.513 H -56.2 -60.2 59.0 0.513 0.0 PCW
 8.513
 N
 C25
ALA B:123 C:519 48.0 0.417 H -60.1 -57.9 48.0 0.417 0.0
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 ALA A:123 A:321 59.0 0.513 H -54.6 -60.9 59.0 0.513 0.0
ALA C:123 C:519 57.0 0.496 H -58.1 -54.6 57.0 0.496 0.0
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 ALA A:123 A:321 58.0 0.504 H -56.1 -60.3 58.0 0.504 0.0 PCW
 9.890
 N
 C17
ALA C:123 C:519 49.0 0.426 H -60.1 -57.9 49.0 0.426 0.0
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 ALA A:123 A:321 62.0 0.539 H -54.8 -60.7 62.0 0.539 0.0
ALA C:123 C:519 59.0 0.513 H -57.2 -57.4 59.0 0.513 0.0
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 ALA A:123 A:321 54.0 0.47 H -55.6 -58.9 54.0 0.47 0.0 PCW
 8.241
 N
 C20
ALA B:123 D:519 51.0 0.443 H -49.5 -58.8 51.0 0.443 0.0
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 ALA A:123 A:321 56.0 0.487 H -57.4 -60.2 56.0 0.487 0.0 PCW
 8.087
 N
 C20
ALA B:123 D:519 53.0 0.461 H -51.8 -58.1 53.0 0.461 0.0
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 ALA C:123 D:364 46.0 0.4 H -53.7 -58.2 46.0 0.4 0.0 7Q9
7Q9
7Q9
 9.129
4.893
9.866
 CB
CB
O
 O32
C22
C314
ALA D:123 E:664 47.0 0.409 H -55.0 -58.5 47.0 0.409 0.0 7Q9
17F
 6.112
6.469
 O
CB
 C23
O4
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 ALA C:123 D:364 46.0 0.4 H -48.6 -61.6 46.0 0.4 0.0 7Q9
7Q9
7Q9
 9.748
8.670
9.999
 N
O
N
 C37
C311
C314
ALA D:123 E:664 51.0 0.443 H -45.6 -57.0 51.0 0.443 0.0 7Q9
17F
 8.151
6.834
 O
CB
 C23
C1Y
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 ALA C:131 NA:NA DO NA DO DO DO NA NA NA
ALA D:131 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 ALA A:165 A:164 46.0 0.4 H -51.1 -54.2 38.0 0.33 0.07 A:P02647:0.07
 HOH
 5.986
 O
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 ALA B:132 B:186 56.0 0.487 H -51.1 -49.2 56.0 0.487 0.0 PX4
PX4
PX4
PX4
 7.958
3.343
8.720
7.300
 HA
HA
HB2
N
 H70
H20
H12
H72
ALA C:132 C:186 43.0 0.374 H -62.7 -42.3 43.0 0.374 0.0 PX4
PX4
PX4
PX4
 8.739
4.149
9.919
7.873
 H
HA
HA
N
 H70
H35
H28
H33
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 ALA B:132 B:186 49.0 0.426 H -51.4 -48.7 49.0 0.426 0.0 PX4
PX4
PX4
PX4
 6.366
2.284
9.582
7.548
 HA
HB2
HB2
H
 H24
H2
H25
H39
ALA C:132 C:186 62.0 0.539 H -62.1 -46.6 62.0 0.539 0.0 PX4
PX4
PX4
 8.152
6.143
7.972
 H
HA
N
 H70
H22
H38
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 ALA A:88 A:164 63.0 0.548 H -54.6 -62.6 63.0 0.548 0.0
ALA B:88 B:164 64.0 0.557 H -54.8 -62.5 64.0 0.557 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 ALA A:188 A:188 46.0 0.4 H -50.3 -54.4