Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706810 . C A CCDS8378.1:NM_000039.1:c.518cGc>cTc_NP_000030.1:p.173R>L Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 ARG A:149 A:149 154.0 0.684 T -69.6 -34.1 154.0 0.684 0.0 POV
POV
POV
POV
 8.899
3.497
4.566
7.229
 O
CD
O
CB
 C35
O31
O22
C214
ARG B:149 B:149 156.0 0.693 S -44.2 -60.2 156.0 0.693 0.0 POV
POV
POV
POV
POV
POV
CLR
 2.612
7.411
8.324
9.267
8.851
2.942
6.813
 NH2
O
O
NH2
N
NH2
NE
 O13
C28
C311
O14
C210
O11
C11
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 ARG A:107 A:149 201.0 0.893 I -49.3 -70.6 186.0 0.827 0.066 D:P02647:0.067
ARG B:107 B:149 158.0 0.702 H -41.2 -35.2 158.0 0.702 0.0
ARG C:107 C:149 200.0 0.889 I -49.3 -70.6 185.0 0.822 0.067 B:P02647:0.067
ARG D:107 D:149 158.0 0.702 H -41.1 -35.2 158.0 0.702 0.0
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 ARG E:106 A0:149 139.0 0.618 T -64.9 -41.1 139.0 0.618 0.0 PEV
PEV
PEV
 8.192
5.272
5.940
 NH2
NH2
NH2
 O2P
C13
N6
ARG F:106 A1:149 137.0 0.609 H -69.2 -50.3 137.0 0.609 0.0 PEV
PGV
 6.700
6.474
 NH1
C
 N6
C7
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 ARG A:106 A:306 137.0 0.609 H -67.9 -42.3 137.0 0.609 0.0 PCW
 8.459
 CA
 C19
ARG B:106 C:504 154.0 0.684 H -64.4 -38.2 154.0 0.684 0.0 PCW
 8.664
 HH21
 C40
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 ARG A:106 A:306 171.0 0.76 H -63.8 -47.3 171.0 0.76 0.0 PCW
 9.016
 CA
 C19
ARG B:106 C:504 157.0 0.698 H -67.1 -35.7 157.0 0.698 0.0 PCW
 8.368
 HH21
 C39
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 ARG A:108 A:306 139.0 0.618 H -66.0 -41.2 139.0 0.618 0.0
ARG B:108 C:504 141.0 0.627 H -65.1 -44.8 141.0 0.627 0.0
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 ARG A:108 A:306 158.0 0.702 H -65.8 -42.3 158.0 0.702 0.0 PCW
 7.575
 N
 C18
ARG B:108 C:504 155.0 0.689 H -69.6 -39.1 155.0 0.689 0.0 PCW
 8.432
 NH2
 C39
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 ARG A:108 A:306 149.0 0.662 H -63.5 -43.6 149.0 0.662 0.0
ARG B:108 C:504 169.0 0.751 H -69.0 -38.3 169.0 0.751 0.0
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 ARG A:108 A:306 156.0 0.693 H -67.4 -36.7 156.0 0.693 0.0
ARG C:108 C:504 166.0 0.738 H -70.7 -34.3 166.0 0.738 0.0
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 ARG A:108 A:306 151.0 0.671 H -63.5 -43.6 151.0 0.671 0.0 PCW
 7.445
 N
 C22
ARG C:108 C:504 169.0 0.751 H -69.0 -38.4 169.0 0.751 0.0
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 ARG A:108 A:306 120.0 0.533 H -64.1 -41.0 120.0 0.533 0.0
ARG C:108 C:504 162.0 0.72 H -62.3 -41.2 162.0 0.72 0.0
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 ARG A:108 A:306 154.0 0.684 H -66.0 -38.0 154.0 0.684 0.0 PCW
 9.449
 HE
 C18
ARG B:108 D:504 150.0 0.667 H -64.6 -39.3 150.0 0.667 0.0 PCW
 9.672
 HH21
 C39
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 ARG A:108 A:306 165.0 0.733 H -67.6 -39.1 165.0 0.733 0.0 PCW
 7.975
 CA
 C18
ARG B:108 D:504 157.0 0.698 H -64.2 -38.2 157.0 0.698 0.0 PCW
 7.217
 HH22
 C39
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 ARG C:108 D:349 159.0 0.707 H -63.5 -47.0 159.0 0.707 0.0 7Q9
7Q9
7Q9
7Q9
7Q9
 9.442
3.024
8.567
2.842
8.971
 CG
HE
O
HH21
N
 C38
C39
C315
O22
C318
ARG D:108 E:649 166.0 0.738 H -65.9 -39.8 166.0 0.738 0.0 7Q9
7Q9
7Q9
7Q9
 3.488
6.301
3.789
9.562
 CD
HH21
HE
HH22
 O22
C311
C23
C23
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 ARG C:108 D:349 123.0 0.547 H -61.3 -46.8 123.0 0.547 0.0 7Q9
7Q9
7Q9
 3.163
7.799
2.925
 HE
CD
HH21
 C39
O22
C23
ARG D:108 E:649 160.0 0.711 H -62.2 -46.7 160.0 0.711 0.0 7Q9
7Q9
7Q9
17F
7Q9
 3.538
9.347
9.431
9.503
7.315
 CG
HH21
HE
O
HH22
 C23
C311
C23
C34
C23
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 ARG C:116 NA:NA DO NA DO DO DO NA NA NA
ARG D:116 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 ARG A:150 A:149 141.0 0.627 H -64.2 -43.8 78.0 0.347 0.28 A:P02647:0.28
 HOH
 8.589
 O
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 ARG B:117 B:171 140.0 0.622 H -60.4 -40.7 140.0 0.622 0.0 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 1.835
1.838
2.233
9.718
9.702
8.384
5.770
9.483
 HH12
HH21
HA
HD3
HD3
HE
HA
HG2
 O1
O1
H63
H20
H3
H42
H31
H44
ARG C:117 C:171 152.0 0.676 H -65.8 -41.8 152.0 0.676 0.0 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 9.078
5.626
7.166
9.627
4.952
4.095
1.863
8.784
6.713
 N
HA
H
HH12
O
HG3
HE
HB2
HD3
 H72
H44
H70
H7
O6
H17
O8
O6
H9
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 ARG B:117 B:171 188.0 0.836 T -60.8 -36.4 188.0 0.836 0.0 PX4
PX4
PX4
PX4
 2.704
3.174
4.155
9.513
 HH11
HA
O
HA
 H5
O8
O2
H17
ARG C:117 C:171 208.0 0.924 H -61.4 -35.2 208.0 0.924 0.0 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 9.757
6.841
7.358
1.640
8.056
1.904
2.777
7.362
9.330
 H
HH11
HG2
HE
HH22
HH22
HH12
HH12
HH11
 H61
H59
H11
O2
H7
O1
H22
H11
H5
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 ARG A:73 A:149 183.0 0.813 H -64.5 -42.9 61.0 0.271 0.542 B:P02647:0.542
ARG B:73 B:149 183.0 0.813 H -60.3 -43.6 58.0 0.258 0.555 A:P02647:0.556

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 ARG A:173 A:173 153.0 0.68 H -68.4 -40.3