Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706874 . C A CCDS8378.1:NM_000039.1:c.454Gag>Tag_NP_000030.1:p.152E>* Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 GLU A:128 A:128 96.0 0.505 T -78.0 -21.7 96.0 0.505 0.0 POV
POV
POV
 4.380
8.743
9.274
 OE2
OE2
N
 O11
O13
C218
GLU B:128 B:128 115.0 0.605 T -85.7 -38.9 115.0 0.605 0.0 POV
POV
POV
CLR
 3.181
4.612
8.853
5.710
 OE1
OE2
OE2
OE2
 C13
C15
O13
O1
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 GLU A:86 A:128 119.0 0.626 H -66.8 -30.2 119.0 0.626 0.0
GLU B:86 B:128 149.0 0.784 H -64.3 -61.7 149.0 0.784 0.0
GLU C:86 C:128 120.0 0.632 H -66.7 -30.3 120.0 0.632 0.0
GLU D:86 D:128 147.0 0.774 H -64.3 -61.6 147.0 0.774 0.0
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 GLU E:85 A0:128 96.0 0.505 H -66.0 -47.6 55.0 0.289 0.216 CA:Q0TCG1:0.216
 PGV
PEV
 8.141
4.803
 OE1
OE1
 O02
C42
GLU F:85 A1:128 102.0 0.537 H -56.0 -43.2 60.0 0.316 0.221 CA:Q0TCG1:0.221
 PGV
PEV
 4.050
7.541
 CG
CG
 C18
C26
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLU A:85 A:285 127.0 0.668 H -60.7 -43.2 127.0 0.668 0.0
GLU B:85 C:483 99.0 0.521 H -64.3 -44.8 99.0 0.521 0.0
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLU A:85 A:285 126.0 0.663 H -58.2 -41.9 126.0 0.663 0.0
GLU B:85 C:483 101.0 0.532 H -62.7 -47.9 101.0 0.532 0.0
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLU A:87 A:285 85.0 0.447 H -64.7 -48.9 85.0 0.447 0.0
GLU B:87 C:483 96.0 0.505 H -64.8 -41.7 96.0 0.505 0.0 PCW
 7.397
 N
 C27
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLU A:87 A:285 129.0 0.679 H -61.3 -46.0 129.0 0.679 0.0
GLU B:87 C:483 105.0 0.553 H -63.9 -39.8 101.0 0.532 0.021 A:P02647:0.021
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLU A:87 A:285 121.0 0.637 H -61.9 -44.0 121.0 0.637 0.0 PCW
 6.667
 N
 C24
GLU B:87 C:483 106.0 0.558 H -65.3 -40.5 106.0 0.558 0.0 PCW
 9.830
 N
 C25
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLU A:87 A:285 129.0 0.679 H -61.4 -37.9 129.0 0.679 0.0
GLU C:87 C:483 93.0 0.489 H -66.7 -41.9 93.0 0.489 0.0 PCW
 8.014
 C
 C27
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 GLU A:87 A:285 122.0 0.642 H -61.9 -44.0 122.0 0.642 0.0
GLU C:87 C:483 106.0 0.558 H -65.3 -40.5 106.0 0.558 0.0 PCW
 8.503
 O
 C27
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLU A:87 A:285 127.0 0.668 H -58.7 -44.1 127.0 0.668 0.0
GLU C:87 C:483 92.0 0.484 H -65.8 -51.3 92.0 0.484 0.0 PCW
 8.638
 O
 C28
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 GLU A:87 A:285 121.0 0.637 H -61.9 -39.7 121.0 0.637 0.0
GLU B:87 D:483 106.0 0.558 H -65.4 -41.8 106.0 0.558 0.0
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 GLU A:87 A:285 122.0 0.642 H -60.0 -47.7 122.0 0.642 0.0
GLU B:87 D:483 85.0 0.447 H -67.0 -41.7 85.0 0.447 0.0
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLU C:87 D:328 104.0 0.547 H -75.5 -48.4 104.0 0.547 0.0 17F
7Q9
7Q9
 7.779
6.706
8.866
 N
O
O
 C42
C311
C318
GLU D:87 E:628 112.0 0.589 H -62.4 -39.3 112.0 0.589 0.0 7Q9
7Q9
 6.610
5.984
 H
OE2
 O32
C32
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLU C:87 D:328 110.0 0.579 H -68.1 -43.5 110.0 0.579 0.0 17F
7Q9
7Q9
7Q9
 7.281
6.653
7.575
8.826
 N
O
H
O
 C31
C311
C318
C318
GLU D:87 E:628 104.0 0.547 H -59.2 -44.9 104.0 0.547 0.0 7Q9
7Q9
 5.930
6.729
 OE1
N
 C3
C311
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 GLU C:95 NA:NA DO NA DO DO DO NA NA NA
GLU D:95 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 GLU A:129 A:128 87.0 0.458 H -66.9 -56.9 87.0 0.458 0.0
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLU B:96 B:150 118.0 0.621 H -61.1 -53.8 118.0 0.621 0.0 PX4
PX4
PX4
PX4
PX4
 7.680
4.822
6.096
8.227
8.949
 O
N
H
N
O
 H43
H29
H48
H45
H44
GLU C:96 C:150 135.0 0.711 H -64.7 -44.4 135.0 0.711 0.0 PX4
PX4
PX4
 5.664
9.954
5.761
 HA
HA
C
 H1
H14
H39
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLU B:96 B:150 124.0 0.653 H -71.1 -30.3 124.0 0.653 0.0 PX4
PX4
PX4
 6.416
6.082
7.380
 N
N
HG3
 H24
H50
H6
GLU C:96 C:150 125.0 0.658 H -62.8 -37.5 125.0 0.658 0.0 PX4
PX4
PX4
PX4
PX4
PX4
 6.865
9.185
6.553
8.724
6.670
9.739
 O
O
N
O
H
HG3
 H41
H18
H25
H34
H17
H10

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 GLU A:152 A:152 125.0 0.658 H -67.7 -46.6