Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706937 . T A CCDS8378.1:NM_000039.1:c.391Aag>Tag_NP_000030.1:p.131K>* Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 LYS A:107 A:107 93.0 0.465 H -67.3 -42.7 19.0 0.095 0.37 B:P02647:0.37
 POV
POV
POV
POV
POV
POV
POV
POV
 9.144
5.506
9.851
9.762
7.481
9.994
3.348
9.768
 CD
C
CD
NZ
CE
NZ
NZ
CE
 C316
C214
C316
C25
C37
C27
C28
C29
LYS B:107 B:107 65.0 0.325 H -155.7 -32.5 22.0 0.11 0.215 A:P02647:0.215
 POV
POV
POV
POV
CLR
 9.232
9.131
9.397
3.397
6.505
 CD
O
N
NZ
C
 C15
C212
O13
C26
C27
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 LYS A:65 A:107 100.0 0.5 H -64.5 -41.8 80.0 0.4 0.1 B:P02647:0.1
LYS B:65 B:107 134.0 0.67 H -73.7 -56.4 80.0 0.4 0.27 A:P02647:0.27
LYS C:65 C:107 102.0 0.51 H -64.5 -41.7 82.0 0.41 0.1 D:P02647:0.1
LYS D:65 D:107 132.0 0.66 H -73.8 -56.4 80.0 0.4 0.26 C:P02647:0.26
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 LYS E:64 A0:107 97.0 0.485 H -59.2 -44.3 59.0 0.295 0.19 F:P02647:0.19
 PEV
PGV
PGV
PEV
PGV
PGV
 5.358
9.858
6.922
4.737
8.092
9.497
 N
N
NZ
NZ
O
NZ
 C41
C06
C2
C42
C18
C10
LYS F:64 A1:107 137.0 0.685 H -64.4 -35.5 102.0 0.51 0.175 E:P02647:0.175
 PEV
PEV
PEV
PEV
PEV
 3.828
7.560
4.403
8.257
8.731
 NZ
NZ
CG
O
NZ
 C47
C13
C21
C26
C26
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 LYS A:64 A:264 94.0 0.47 H -65.8 -40.6 34.0 0.17 0.3 B:P02647:0.3
LYS B:64 C:462 86.0 0.43 H -71.7 -34.1 20.0 0.1 0.33 A:P02647:0.33
 PCW
PCW
17F
17F
 9.343
3.586
9.390
6.605
 HZ1
CE
C
O
 C44
C28
C2X
C42
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 LYS A:64 A:264 104.0 0.52 H -63.3 -36.2 37.0 0.185 0.335 B:P02647:0.335
LYS B:64 C:462 78.0 0.39 H -66.0 -36.7 21.0 0.105 0.285 A:P02647:0.285
 PCW
17F
17F
 4.353
9.612
6.084
 CD
CD
O
 C28
C23
C39
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 LYS A:66 A:264 98.0 0.49 H -64.6 -45.6 39.0 0.195 0.295 B:P02647:0.295
LYS B:66 C:462 85.0 0.425 H -61.9 -44.9 14.0 0.07 0.355 A:P02647:0.355
 PCW
PCW
 9.060
7.330
 CG
CD
 C22
C28
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 LYS A:66 A:264 99.0 0.495 H -67.2 -36.0 38.0 0.19 0.305 B:P02647:0.305
LYS B:66 C:462 78.0 0.39 H -66.2 -39.0 17.0 0.085 0.305 A:P02647:0.305
 PCW
PCW
17F
 8.362
3.956
8.056
 CE
CD
O
 C43
C28
C40
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 LYS A:66 A:264 95.0 0.475 H -70.6 -35.1 38.0 0.19 0.285 B:P02647:0.285
LYS B:66 C:462 85.0 0.425 H -65.0 -39.2 15.0 0.075 0.35 A:P02647:0.35
 PCW
PCW
 9.429
9.527
 CE
CE
 C28
C25
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 LYS A:66 A:264 84.0 0.42 H -58.1 -50.2 44.0 0.22 0.2 C:P02647:0.2
LYS C:66 C:462 79.0 0.395 H -64.7 -36.9 13.0 0.065 0.33 A:P02647:0.33
 PCW
 9.807
 CD
 C26
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 LYS A:66 A:264 93.0 0.465 H -70.6 -35.1 37.0 0.185 0.28 C:P02647:0.28
LYS C:66 C:462 82.0 0.41 H -65.0 -39.3 15.0 0.075 0.335 A:P02647:0.335
 PCW
PCW
 6.274
5.849
 CE
CD
 C20
C28
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 LYS A:66 A:264 98.0 0.49 H -65.3 -47.0 41.0 0.205 0.285 C:P02647:0.285
LYS C:66 C:462 71.0 0.355 H -62.9 -44.7 4.0 0.02 0.335 A:P02647:0.335
 PCW
PCW
 9.514
9.627
 CE
CD
 C19
C24
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 LYS A:66 A:264 103.0 0.515 H -63.7 -35.1 40.0 0.2 0.315 B:P02647:0.315
LYS B:66 D:462 84.0 0.42 H -67.4 -39.1 13.0 0.065 0.355 A:P02647:0.355
 PCW
PCW
17F
17F
 7.281
3.495
9.736
6.378
 CD
CB
O
O
 C41
C28
C23
C40
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 LYS A:66 A:264 99.0 0.495 H -63.2 -40.9 36.0 0.18 0.315 B:P02647:0.315
LYS B:66 D:462 79.0 0.395 H -67.0 -41.5 13.0 0.065 0.33 A:P02647:0.33
 PCW
PCW
17F
17F
 7.837
4.238
9.573
5.732
 CD
CD
C
O
 C43
C28
C2X
C39
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 LYS C:66 D:307 125.0 0.625 H -68.3 -53.7 115.0 0.575 0.05 D:P02647:0.05
 17F
 9.880
 H
 C10
LYS D:66 E:607 135.0 0.675 H -56.1 -39.5 133.0 0.665 0.01 C:P02647:0.01
 7Q9
7Q9
 9.784
7.565
 N
H
 C311
C313
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 LYS C:66 D:307 135.0 0.675 H -60.6 -42.2 121.0 0.605 0.07 D:P02647:0.07
 17F
7Q9
 9.486
9.440
 C
H
 C36
C35
LYS D:66 E:607 131.0 0.655 H -64.9 -57.0 126.0 0.63 0.025 C:P02647:0.025
 7Q9
7Q9
 7.130
8.894
 C
H
 C317
C38
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 LYS C:74 NA:NA DO NA DO DO DO NA NA NA
LYS D:74 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 LYS A:108 A:107 90.0 0.45 H -72.6 -41.1 69.0 0.345 0.105 A:P02647:0.105
 HOH
 2.650
 NZ
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 LYS B:75 B:129 110.0 0.55 H -80.6 -32.0 110.0 0.55 0.0 PX4
PX4
PX4
 9.311
5.947
8.065
 H
N
H
 H60
H51
H46
LYS C:75 C:129 94.0 0.47 H -68.4 -36.1 80.0 0.4 0.07 B:P02647:0.07
 PX4
PX4
 9.435
7.624
 HB3
C
 H66
H42
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 LYS B:75 B:129 125.0 0.625 H -62.7 -52.4 125.0 0.625 0.0 PX4
PX4
PX4
PX4
 8.105
8.352
9.733
7.673
 C
H
C
HB3
 H57
H29
H45
H69
LYS C:75 C:129 140.0 0.7 H -66.4 -45.4 140.0 0.7 0.0 PX4
 9.166
 O
 H71
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 LYS A:53 A:107 133.0 0.665 H -73.2 -47.2 133.0 0.665 0.0
LYS B:53 B:107 132.0 0.66 H -73.0 -47.4 132.0 0.66 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 LYS A:131 A:131 109.0 0.545 H -59.4 -40.2