Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706964 . G A CCDS8378.1:NM_000039.1:c.364Cag>Tag_NP_000030.1:p.122Q>* Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 GLN A:98 A:98 147.0 0.817 T -75.3 -42.4 147.0 0.817 0.0 POV
POV
POV
POV
POV
POV
 4.172
3.091
9.605
6.173
6.317
9.129
 OE1
NE2
NE2
OE1
N
O
 O32
O32
C14
C15
C210
C11
GLN B:98 B:98 118.0 0.656 H -37.8 -49.8 118.0 0.656 0.0 POV
POV
POV
POV
POV
CLR
 2.866
3.695
5.590
9.816
5.985
6.536
 NE2
OE1
NE2
OE1
O
O
 O22
C15
C218
C24
C14
C6
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 GLN A:56 A:98 78.0 0.433 H -32.5 -66.7 65.0 0.361 0.072 D:P02647:0.072
GLN B:56 B:98 76.0 0.422 H -47.7 -48.8 76.0 0.422 0.0
GLN C:56 C:98 79.0 0.439 H -32.5 -66.7 66.0 0.367 0.072 B:P02647:0.072
GLN D:56 D:98 76.0 0.422 H -47.7 -48.8 76.0 0.422 0.0
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 GLN E:55 A0:98 99.0 0.55 G -67.3 -47.6 99.0 0.55 0.0 PEV
PEV
PGV
PEV
PGV
PEV
 9.685
9.833
3.479
3.033
7.080
8.700
 OE1
NE2
OE1
OE1
CB
C
 C47
C48
C6
O1P
C31
C26
GLN F:55 A1:98 100.0 0.556 H -62.0 -42.5 100.0 0.556 0.0 PEV
PGV
PEV
PEV
 3.272
6.731
9.532
7.844
 O
O
O
C
 N6
O14
C40
C25
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLN A:55 A:255 127.0 0.706 H -60.1 -61.1 127.0 0.706 0.0
GLN B:55 C:453 136.0 0.756 H -56.6 -59.8 136.0 0.756 0.0 PCW
 6.347
 N
 C28
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLN A:55 A:255 132.0 0.733 H -64.5 -59.8 132.0 0.733 0.0
GLN B:55 C:453 136.0 0.756 H -56.4 -59.7 136.0 0.756 0.0 PCW
 9.006
 H
 C28
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLN A:57 A:255 134.0 0.744 H -59.7 -59.1 134.0 0.744 0.0
GLN B:57 C:453 120.0 0.667 H -62.9 -65.6 120.0 0.667 0.0 PCW
 7.053
 N
 C28
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLN A:57 A:255 133.0 0.739 H -64.4 -63.4 133.0 0.739 0.0
GLN B:57 C:453 137.0 0.761 H -55.1 -58.7 137.0 0.761 0.0 PCW
 6.770
 N
 C28
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLN A:57 A:255 124.0 0.689 H -61.2 -60.9 124.0 0.689 0.0
GLN B:57 C:453 146.0 0.811 H -57.4 -60.6 146.0 0.811 0.0
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLN A:57 A:255 132.0 0.733 H -59.3 -61.1 132.0 0.733 0.0 PCW
 9.613
 N
 C28
GLN C:57 C:453 131.0 0.728 H -55.1 -61.5 131.0 0.728 0.0
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 GLN A:57 A:255 125.0 0.694 H -61.1 -61.0 125.0 0.694 0.0
GLN C:57 C:453 147.0 0.817 H -57.5 -60.6 147.0 0.817 0.0 PCW
 8.948
 N
 C28
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLN A:57 A:255 137.0 0.761 H -62.3 -61.7 137.0 0.761 0.0
GLN C:57 C:453 134.0 0.744 H -57.4 -59.6 134.0 0.744 0.0
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 GLN A:57 A:255 127.0 0.706 H -60.1 -65.1 127.0 0.706 0.0
GLN B:57 D:453 133.0 0.739 H -57.3 -57.2 133.0 0.739 0.0 PCW
 6.210
 N
 C28
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 GLN A:57 A:255 126.0 0.7 H -63.4 -64.2 126.0 0.7 0.0
GLN B:57 D:453 135.0 0.75 H -56.7 -58.6 135.0 0.75 0.0 PCW
 7.197
 N
 C28
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLN C:57 D:298 106.0 0.589 H -57.8 -56.6 106.0 0.589 0.0 7Q9
17F
7Q9
 5.773
9.010
5.973
 OE1
O
HE22
 C32
C10
C23
GLN D:57 E:598 113.0 0.628 H -50.3 -58.3 113.0 0.628 0.0 7Q9
7Q9
7Q9
 7.929
4.851
5.921
 HE22
OE1
HE22
 C37
C15
C23
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLN C:57 D:298 90.0 0.5 H -53.4 -55.3 90.0 0.5 0.0 7Q9
17F
7Q9
7Q9
 4.011
8.891
2.701
8.053
 NE2
HE21
HE22
OE1
 C32
C10
C23
C35
GLN D:57 E:598 131.0 0.728 H -51.5 -54.3 131.0 0.728 0.0 7Q9
7Q9
7Q9
17F
7Q9
7Q9
7Q9
7Q9
 7.393
7.838
8.679
9.396
8.601
8.471
4.809
3.332
 OE1
HE21
OE1
HE22
HE22
HE21
O
OE1
 C318
C318
C310
C22
C318
C316
C37
C310
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 GLN C:65 NA:NA DO NA DO DO DO NA NA NA
GLN D:65 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 GLN A:99 A:98 65.0 0.361 H -59.7 -37.5 65.0 0.361 0.0 HOH
 2.774
 OE1
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLN B:44 B:98 90.0 0.5 H -59.2 -36.0 90.0 0.5 0.0 PX4
PX4
PX4
PX4
PX4
 9.287
3.438
9.317
9.278
6.237
 HE21
OE1
OE1
OE1
HA
 H51
H12
O2
H70
H70
GLN C:44 C:98 108.0 0.6 H -41.9 -50.0 108.0 0.6 0.0 PX4
PX4
PX4
 6.860
6.907
5.682
 HE21
N
H
 O6
H29
H69
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLN B:44 B:98 118.0 0.656 H -37.5 -58.7 118.0 0.656 0.0 PX4
PX4
PX4
PX4
 9.423
4.130
6.790
9.231
 HE21
HE21
OE1
O
 H9
H5
H10
H43
GLN C:44 C:98 110.0 0.611 S -62.1 -38.5 110.0 0.611 0.0 PX4
PX4
PX4
PX4
 6.416
6.673
2.373
7.371
 OE1
HE22
HG2
HG2
 H46
H6
H24
H32
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 GLN A:44 A:98 130.0 0.722 H -44.4 -65.0 130.0 0.722 0.0
GLN B:44 B:98 131.0 0.728 H -43.5 -66.2 131.0 0.728 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 GLN A:122 A:122 106.0 0.589 H -50.1 -49.7