Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116706972 . G A CCDS8378.1:NM_000039.1:c.356gCc>gTc_NP_000030.1:p.119A>V Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 ALA A:95 A:95 60.0 0.522 H -63.8 -3.7 60.0 0.522 0.0 POV
POV
POV
POV
POV
 9.518
7.314
3.365
8.544
4.106
 O
N
CB
N
O
 C15
C24
O22
C13
O14
ALA B:95 B:95 60.0 0.522 H -114.8 -42.1 60.0 0.522 0.0 POV
POV
POV
POV
POV
 5.465
5.235
3.726
8.097
7.395
 O
N
CB
N
O
 C14
C14
C13
C24
C32
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 ALA A:53 A:95 59.0 0.513 H -76.8 -41.2 59.0 0.513 0.0
ALA B:53 B:95 63.0 0.548 H -54.2 -68.4 63.0 0.548 0.0
ALA C:53 C:95 61.0 0.53 H -76.8 -41.2 61.0 0.53 0.0
ALA D:53 D:95 62.0 0.539 H -54.1 -68.4 62.0 0.539 0.0
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 ALA E:52 A0:95 48.0 0.417 H -79.1 -7.5 46.0 0.4 0.017 F:P02647:0.017
 PEV
PGV
PEV
PGV
PEV
PEV
 5.785
3.945
5.972
3.633
7.996
7.962
 CB
CB
N
O
CB
O
 C48
C9
O1P
C31
C20
C26
ALA F:52 A1:95 50.0 0.435 H -80.5 53.4 50.0 0.435 0.0 PEV
PEV
PEV
PEV
PEV
PGV
PEV
PEV
 7.878
8.924
6.012
3.287
9.091
3.749
7.663
7.835
 CB
O
O
CA
CB
CB
CB
O
 C22
C44
C42
O1P
C26
C13
O11
C24
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 ALA A:52 A:252 53.0 0.461 H -69.2 -41.3 53.0 0.461 0.0 PCW
 8.825
 H
 C28
ALA B:52 C:450 61.0 0.53 H -90.3 22.1 57.0 0.496 0.034 A:P02647:0.035
 PCW
 6.192
 O
 C28
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 ALA A:52 A:252 53.0 0.461 H -78.0 -43.9 53.0 0.461 0.0 PCW
 8.756
 H
 C28
ALA B:52 C:450 61.0 0.53 H -66.9 -19.8 61.0 0.53 0.0 PCW
 9.216
 C
 C28
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:54 A:252 58.0 0.504 I -60.8 -30.7 58.0 0.504 0.0
ALA B:54 C:450 56.0 0.487 H -70.8 -37.9 56.0 0.487 0.0 PCW
 7.858
 C
 C28
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:54 A:252 58.0 0.504 H -68.4 -30.6 58.0 0.504 0.0 PCW
 9.903
 N
 C28
ALA B:54 C:450 64.0 0.557 H -78.5 0.7 58.0 0.504 0.053 A:P02647:0.052
 PCW
 6.847
 C
 C28
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 ALA A:54 A:252 70.0 0.609 H -62.9 -34.7 70.0 0.609 0.0
ALA B:54 C:450 62.0 0.539 H -67.3 -11.8 62.0 0.539 0.0
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 ALA A:54 A:252 51.0 0.443 H -63.6 -41.7 51.0 0.443 0.0 PCW
 9.877
 N
 C28
ALA C:54 C:450 55.0 0.478 H -69.8 -10.1 53.0 0.461 0.017 A:P02647:0.017
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 ALA A:54 A:252 70.0 0.609 H -63.0 -34.7 70.0 0.609 0.0
ALA C:54 C:450 61.0 0.53 H -67.3 -11.7 61.0 0.53 0.0
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 ALA A:54 A:252 58.0 0.504 H -61.9 -33.2 58.0 0.504 0.0
ALA C:54 C:450 70.0 0.609 H -76.6 -4.2 59.0 0.513 0.096 A:P02647:0.096
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 ALA A:54 A:252 48.0 0.417 H -84.9 -43.7 48.0 0.417 0.0 PCW
 9.047
 H
 C27
ALA B:54 D:450 72.0 0.626 H -97.1 10.6 69.0 0.6 0.026 A:P02647:0.026
 PCW
 6.690
 C
 C28
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 ALA A:54 A:252 55.0 0.478 H -75.1 -38.0 55.0 0.478 0.0
ALA B:54 D:450 63.0 0.548 H -89.6 17.8 63.0 0.548 0.0 PCW
 7.502
 C
 C28
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 ALA C:54 D:295 50.0 0.435 H -72.2 -31.6 50.0 0.435 0.0 7Q9
7Q9
7Q9
 8.295
9.589
8.887
 N
CB
H
 C32
C23
C310
ALA D:54 E:595 44.0 0.383 H -61.4 -25.3 44.0 0.383 0.0 7Q9
7Q9
7Q9
 7.686
8.367
7.541
 H
O
H
 C37
C13
C23
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 ALA C:54 D:295 55.0 0.478 H -80.6 -15.8 55.0 0.478 0.0 7Q9
7Q9
7Q9
 7.582
7.667
6.106
 CA
CB
H
 C32
C23
C312
ALA D:54 E:595 61.0 0.53 H -71.6 -14.4 61.0 0.53 0.0 7Q9
7Q9
 8.394
5.976
 CB
N
 C37
C317
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 ALA C:62 NA:NA DO NA DO DO DO NA NA NA
ALA D:62 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 ALA A:96 A:95 64.0 0.557 H -63.4 -52.8 64.0 0.557 0.0 HOH
 4.599
 N
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 ALA B:41 B:95 68.0 0.591 H -56.2 -28.6 68.0 0.591 0.0 PX4
 9.103
 HA
 H7
ALA C:41 C:95 57.0 0.496 H -59.3 -38.1 57.0 0.496 0.0 PX4
PX4
PX4
PX4
 8.540
8.788
9.312
5.454
 H
H
N
N
 H45
H21
H29
H68
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 ALA B:41 B:95 68.0 0.591 H -59.8 -42.6 68.0 0.591 0.0 PX4
 8.044
 H
 O2
ALA C:41 C:95 63.0 0.548 H -66.8 -36.3 63.0 0.548 0.0 PX4
PX4
 7.053
5.970
 H
N
 O8
H28
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 ALA A:41 A:95 73.0 0.635 H -62.5 -33.7 73.0 0.635 0.0
ALA B:41 B:95 74.0 0.643 H -61.1 -34.9 74.0 0.643 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 ALA A:119 A:119 65.0 0.565 H -63.0 -37.4