Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116707006 . G A CCDS8378.1:NM_000039.1:c.322Cag>Tag_NP_000030.1:p.108Q>* Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 GLN A:84 A:84 125.0 0.694 H -98.8 -39.6 125.0 0.694 0.0 POV
POV
 8.076
6.978
 CG
C
 C14
C311
GLN B:84 B:84 117.0 0.65 H -71.1 -45.0 117.0 0.65 0.0 POV
POV
POV
POV
 3.134
9.213
7.026
9.616
 OE1
N
O
N
 C15
C25
C33
O32
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 GLN A:42 A:84 145.0 0.806 H -80.8 -37.5 145.0 0.806 0.0
GLN B:42 B:84 150.0 0.833 H -59.2 -50.4 150.0 0.833 0.0
GLN C:42 C:84 145.0 0.806 H -80.8 -37.6 145.0 0.806 0.0
GLN D:42 D:84 153.0 0.85 H -59.2 -50.4 153.0 0.85 0.0
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 GLN E:41 A0:84 95.0 0.528 H -60.5 -43.0 95.0 0.528 0.0 PEV
PEV
PEV
PEV
PEV
PEV
PEV
PGV
PEV
 3.641
3.616
4.324
7.274
7.012
3.952
5.541
7.256
8.460
 NE2
OE1
NE2
O
CG
CB
O
NE2
OE1
 O11
C45
C20
C25
C24
C25
C47
C11
C26
GLN F:41 A1:84 105.0 0.583 H -94.6 10.9 105.0 0.583 0.0 PGV
PEV
PGV
PEV
PEV
 6.701
3.752
7.668
5.153
3.689
 C
OE1
O
OE1
NE2
 C18
C19
C18
N6
C17
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLN A:41 A:241 116.0 0.644 H -74.5 -32.6 116.0 0.644 0.0 PCW
 8.144
 H
 C44
GLN B:41 C:439 143.0 0.794 H -62.9 -44.7 117.0 0.65 0.144 A:P02647:0.144
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 GLN A:41 A:241 112.0 0.622 H -67.3 -42.7 112.0 0.622 0.0 PCW
 9.557
 H
 C44
GLN B:41 C:439 141.0 0.783 H -64.9 -33.0 130.0 0.722 0.061 A:P02647:0.061
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLN A:43 A:241 136.0 0.756 H -65.2 -35.2 136.0 0.756 0.0
GLN B:43 C:439 133.0 0.739 H -68.9 -42.4 124.0 0.689 0.05 A:P02647:0.05
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLN A:43 A:241 107.0 0.594 H -65.4 -39.8 107.0 0.594 0.0
GLN B:43 C:439 135.0 0.75 H -65.3 -36.9 112.0 0.622 0.128 A:P02647:0.128
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 GLN A:43 A:241 119.0 0.661 H -58.3 -45.3 119.0 0.661 0.0 PCW
 8.435
 N
 C45
GLN B:43 C:439 132.0 0.733 H -111.4 -23.7 116.0 0.644 0.089 A:P02647:0.089
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLN A:43 A:241 132.0 0.733 H -59.5 -40.8 132.0 0.733 0.0
GLN C:43 C:439 125.0 0.694 H -63.0 -33.8 111.0 0.617 0.077 A:P02647:0.078
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 GLN A:43 A:241 120.0 0.667 H -58.3 -45.3 120.0 0.667 0.0
GLN C:43 C:439 131.0 0.728 H -111.5 -23.7 113.0 0.628 0.1 A:P02647:0.1
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 GLN A:43 A:241 126.0 0.7 H -61.4 -43.5 126.0 0.7 0.0
GLN C:43 C:439 102.0 0.567 H -100.0 -27.3 102.0 0.567 0.0
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 GLN A:43 A:241 128.0 0.711 H -73.5 -38.5 128.0 0.711 0.0
GLN B:43 D:439 142.0 0.789 H -64.9 -33.3 111.0 0.617 0.172 A:P02647:0.172
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 GLN A:43 A:241 121.0 0.672 H -72.5 -32.4 121.0 0.672 0.0
GLN B:43 D:439 136.0 0.756 H -66.3 -35.4 122.0 0.678 0.078 A:P02647:0.078
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLN C:43 D:284 110.0 0.611 H -60.9 -40.9 110.0 0.611 0.0 7Q9
7Q9
 5.177
5.839
 HE21
HE21
 C14
C23
GLN D:43 E:584 119.0 0.661 H -58.4 -50.1 119.0 0.661 0.0 7Q9
7Q9
 8.308
6.386
 N
O
 C316
C39
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 GLN C:43 D:284 107.0 0.594 H -62.8 -36.9 107.0 0.594 0.0 7Q9
7Q9
 6.952
4.831
 HE22
HE22
 O32
C23
GLN D:43 E:584 124.0 0.689 H -60.7 -46.9 124.0 0.689 0.0 7Q9
7Q9
 8.500
7.522
 N
O
 C318
C39
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 GLN C:51 C:52 109.0 0.606 H -64.5 -36.4 109.0 0.606 0.0
GLN D:51 D:52 106.0 0.589 H -65.0 -36.5 106.0 0.589 0.0
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 GLN A:85 A:84 121.0 0.672 H -53.1 -47.0 121.0 0.672 0.0 HOH
 6.015
 N
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLN B:30 B:84 150.0 0.833 H -72.4 -33.7 150.0 0.833 0.0 PX4
 6.873
 OE1
 H5
GLN C:30 C:84 119.0 0.661 H -58.2 -42.2 119.0 0.661 0.0 PX4
PX4
PX4
 2.824
8.172
9.108
 HA
HA
HA
 H2
H27
H49
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 GLN B:30 B:84 92.0 0.511 H -65.8 -41.5 92.0 0.511 0.0 PX4
PX4
PX4
PX4
PX4
 6.332
8.128
4.543
9.456
9.932
 HE21
N
HE21
HE21
HE21
 O1
H46
O1
H8
H5
GLN C:30 C:84 94.0 0.522 H -62.7 -41.8 94.0 0.522 0.0 PX4
PX4
PX4
 6.649
5.545
7.778
 OE1
N
HE21
 O8
H57
H2
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 GLN A:30 A:84 142.0 0.789 H -59.6 -44.7 142.0 0.789 0.0
GLN B:30 B:84 142.0 0.789 H -59.7 -44.9 142.0 0.789 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 GLN A:108 A:108 132.0 0.733 H -67.5 -43.5