Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116707020 . G A CCDS8378.1:NM_000039.1:c.308aCa>aTa_NP_000030.1:p.103T>I Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 THR A:79 A:79 57.0 0.407 H -63.5 -32.8 57.0 0.407 0.0 POV
POV
POV
POV
POV
POV
 6.348
3.463
8.198
8.774
5.993
6.148
 OG1
OG1
O
OG1
CG2
OG1
 C26
C28
C313
C211
C27
C35
THR B:79 B:79 81.0 0.579 H -105.2 -19.2 81.0 0.579 0.0 POV
POV
POV
POV
POV
POV
POV
 3.668
6.675
8.656
5.529
6.809
9.062
3.274
 OG1
OG1
O
CG2
CG2
OG1
OG1
 C215
C212
C37
C25
C311
C39
C35
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 THR A:37 A:79 95.0 0.679 H -50.6 -78.4 22.0 0.157 0.522 D:P02647:0.407
B:P02647:0.136
THR B:37 B:79 88.0 0.629 H -33.1 -71.8 8.0 0.057 0.572 A:P02647:0.136
C:P02647:0.514
THR C:37 C:79 97.0 0.693 H -50.7 -78.3 24.0 0.171 0.522 D:P02647:0.143
B:P02647:0.393
THR D:37 D:79 88.0 0.629 H -33.1 -71.8 8.0 0.057 0.572 A:P02647:0.5
C:P02647:0.129
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 THR E:36 A0:79 62.0 0.443 H -63.5 -36.3 62.0 0.443 0.0 PEV
PEV
PEV
PEV
PEV
PEV
 8.461
6.349
8.898
7.617
6.889
8.198
 OG1
OG1
C
O
N
C
 C25
O4P
C41
C16
C26
C48
THR F:36 A1:79 78.0 0.557 H -64.1 -38.3 78.0 0.557 0.0 PGV
PEV
 5.916
8.017
 N
C
 C15
C21
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 THR A:36 A:236 51.0 0.364 H -66.3 -38.8 51.0 0.364 0.0 PCW
PCW
 9.799
5.868
 CG2
CG2
 C48
C42
THR B:36 C:434 47.0 0.336 H -58.7 -50.5 47.0 0.336 0.0
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 THR A:36 A:236 44.0 0.314 H -62.9 -46.4 44.0 0.314 0.0 PCW
PCW
PCW
 8.893
5.506
8.488
 CG2
CG2
CG2
 C48
C44
C19
THR B:36 C:434 47.0 0.336 H -56.8 -54.1 47.0 0.336 0.0
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 THR A:38 A:236 55.0 0.393 H -67.9 -29.1 55.0 0.393 0.0 PCW
 4.244
 CG2
 C46
THR B:38 C:434 50.0 0.357 H -63.4 -33.8 50.0 0.357 0.0
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 THR A:38 A:236 44.0 0.314 H -66.5 -33.2 44.0 0.314 0.0 PCW
PCW
PCW
 8.729
5.137
9.469
 CG2
CG2
CG2
 C48
C42
C20
THR B:38 C:434 59.0 0.421 H -60.0 -53.7 59.0 0.421 0.0 PCW
 9.771
 N
 C47
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 THR A:38 A:236 41.0 0.293 H -62.9 -35.9 22.0 0.157 0.136 C:P01116:0.136
 PCW
 5.692
 CG2
 C44
THR B:38 C:434 48.0 0.343 H -63.8 -42.8 48.0 0.343 0.0
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 THR A:38 A:236 62.0 0.443 H -68.6 -31.2 62.0 0.443 0.0 PCW
PCW
 9.781
6.114
 CG2
CG2
 C48
C41
THR C:38 C:434 67.0 0.479 H -69.9 -40.3 67.0 0.479 0.0
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 THR A:38 A:236 40.0 0.286 H -63.0 -35.9 40.0 0.286 0.0 PCW
 6.852
 CG2
 C44
THR C:38 C:434 47.0 0.336 H -63.8 -42.9 47.0 0.336 0.0
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 THR A:38 A:236 55.0 0.393 H -61.5 -35.7 55.0 0.393 0.0 PCW
 7.504
 CG2
 C43
THR C:38 C:434 65.0 0.464 H -64.0 -46.6 65.0 0.464 0.0
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 THR A:38 A:236 50.0 0.357 H -68.0 -35.5 50.0 0.357 0.0 PCW
 5.382
 CG2
 C41
THR B:38 D:434 58.0 0.414 H -61.9 -38.8 58.0 0.414 0.0
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 THR A:38 A:236 52.0 0.371 H -70.5 -30.1 52.0 0.371 0.0
THR B:38 D:434 44.0 0.314 H -61.8 -50.8 44.0 0.314 0.0
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 THR C:38 D:279 60.0 0.429 H -71.4 -28.1 20.0 0.143 0.286 D:P02647:0.286
 17F
7Q9
17F
7Q9
 8.129
6.475
7.675
8.862
 CB
O
CG2
HG1
 C30
C315
C28
C318
THR D:38 E:579 61.0 0.436 H -68.2 -29.0 5.0 0.036 0.4 C:P02647:0.4
 7Q9
7Q9
 7.523
7.812
 HG1
HG1
 C318
C318
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 THR C:38 D:279 63.0 0.45 H -64.0 -34.9 10.0 0.071 0.379 D:P02647:0.379
 17F
7Q9
17F
7Q9
7Q9
 7.601
6.949
8.002
8.170
9.749
 HG1
C
CG2
HG1
CG2
 C30
C316
C28
C317
C318
THR D:38 E:579 54.0 0.386 H -69.2 -29.6 8.0 0.057 0.329 C:P02647:0.329
 7Q9
7Q9
 9.392
8.183
 HG1
O
 C314
C318
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 THR C:46 C:47 39.0 0.279 H -104.1 5.1 31.0 0.221 0.058 A:P0DTC3:0.057
THR D:46 D:47 38.0 0.271 T -108.0 14.2 31.0 0.221 0.05 B:P0DTC3:0.05
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 THR A:80 A:79 42.0 0.3 H -55.5 -46.7 42.0 0.3 0.0 HOH
 8.490
 O
 O
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 THR B:25 B:79 54.0 0.386 H -56.1 -41.2 22.0 0.157 0.229 C:P02647:0.229
 PX4
PX4
PX4
 6.207
6.430
5.439
 HG1
HG22
HG21
 H30
O8
O1
THR C:25 C:79 60.0 0.429 H -60.5 -32.7 43.0 0.307 0.122 B:P02647:0.121
 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 5.841
3.771
6.070
5.425
2.657
8.312
9.663
7.343
 HG22
HG22
HG23
HG22
HG23
HG22
HG21
HG21
 H42
H69
H43
H21
H59
H50
H48
H22
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 THR B:25 B:79 80.0 0.571 H -66.7 -45.0 73.0 0.521 0.05 C:P02647:0.05
 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 2.765
9.330
2.406
9.305
7.736
7.847
7.548
8.857
 HB
HG21
HG23
HG23
HG22
HG23
HG23
HG23
 H47
H52
H67
H22
H11
H28
H68
H43
THR C:25 C:79 74.0 0.529 H -65.7 -46.7 74.0 0.529 0.0 PX4
PX4
PX4
PX4
PX4
PX4
PX4
 3.046
7.196
2.341
2.539
6.371
7.197
6.357
 HG1
HG22
HG22
HG23
HG23
HG1
HG22
 H71
H13
H49
H62
H35
H68
H48
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 THR A:25 A:79 53.0 0.379 H -62.1 -26.0 44.0 0.314 0.065 B:P02647:0.064
THR B:25 B:79 54.0 0.386 H -62.1 -25.9 44.0 0.314 0.072 A:P02647:0.071

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 THR A:103 A:103 70.0 0.5 H -68.9 -36.8