Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116707032 . A C CCDS8378.1:NM_000039.1:c.296cTg>cGg_NP_000030.1:p.99L>R Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 LEU A:75 A:75 69.0 0.406 H -102.8 -8.6 59.0 0.347 0.059 B:P02647:0.059
 POV
POV
POV
POV
POV
POV
 8.860
4.211
9.406
3.506
9.369
8.296
 CD1
CD2
CG
CB
CD1
CD2
 C215
C218
C37
C210
C36
C217
LEU B:75 B:75 67.0 0.394 T -142.7 -15.4 43.0 0.253 0.141 A:P02647:0.141
 POV
POV
POV
POV
POV
 5.251
9.714
6.841
3.457
8.449
 O
O
CD2
CG
CD1
 C214
C210
C37
C39
C212
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 LEU A:33 A:75 76.0 0.447 H -65.8 -73.6 49.0 0.288 0.159 D:P02647:0.147
B:P02647:0.018
LEU B:33 B:75 95.0 0.559 H -63.3 -67.9 20.0 0.118 0.441 A:P02647:0.053
C:P02647:0.394
LEU C:33 C:75 78.0 0.459 H -65.8 -73.6 51.0 0.3 0.159 D:P02647:0.018
B:P02647:0.141
LEU D:33 D:75 93.0 0.547 H -63.2 -68.0 19.0 0.112 0.435 A:P02647:0.382
C:P02647:0.053
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 LEU E:32 A0:75 86.0 0.506 H -62.5 -49.6 86.0 0.506 0.0 PEV
PEV
PEV
PEV
 7.140
9.261
8.291
8.780
 C
O
O
C
 C25
O4P
C26
C48
LEU F:32 A1:75 100.0 0.588 H -62.0 -46.4 100.0 0.588 0.0 PGV
PEV
 6.238
8.958
 N
N
 C11
C48
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 LEU A:32 A:232 62.0 0.365 H -61.7 -36.5 60.0 0.353 0.012 B:P02647:0.012
 PCW
PCW
 6.038
9.365
 CD2
O
 C48
C42
LEU B:32 C:430 63.0 0.371 H -62.2 -37.5 63.0 0.371 0.0 PCW
 9.239
 CD2
 C48
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 LEU A:32 A:232 63.0 0.371 H -61.9 -37.2 58.0 0.341 0.03 B:P02647:0.029
 PCW
PCW
PCW
 3.577
6.972
9.834
 CD1
CD2
CD2
 C48
C48
C18
LEU B:32 C:430 63.0 0.371 H -60.7 -35.3 63.0 0.371 0.0
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 LEU A:34 A:232 70.0 0.412 H -65.6 -32.9 68.0 0.4 0.012 B:P02647:0.012
 PCW
PCW
PCW
 4.847
4.159
8.435
 CD1
CD2
CD2
 C48
C47
C48
LEU B:34 C:430 77.0 0.453 H -64.4 -36.2 77.0 0.453 0.0
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 LEU A:34 A:232 68.0 0.4 H -67.8 -32.6 65.0 0.382 0.018 B:P02647:0.018
 PCW
PCW
 3.948
6.949
 CD1
CD2
 C48
C46
LEU B:34 C:430 60.0 0.353 H -59.4 -34.9 60.0 0.353 0.0 PCW
 7.888
 CD2
 C48
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 LEU A:34 A:232 53.0 0.312 H -63.8 -39.7 53.0 0.312 0.0 PCW
PCW
 8.723
9.663
 O
CD2
 C44
C48
LEU B:34 C:430 84.0 0.494 H -61.2 -34.1 84.0 0.494 0.0 PCW
 8.729
 CD2
 C26
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 LEU A:34 A:232 74.0 0.435 H -61.0 -40.2 73.0 0.429 0.006 C:P02647:0.006
 PCW
PCW
 5.365
7.876
 CD2
CD2
 C48
C47
LEU C:34 C:430 65.0 0.382 H -66.2 -26.0 65.0 0.382 0.0
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 LEU A:34 A:232 51.0 0.3 H -63.8 -39.8 51.0 0.3 0.0 PCW
PCW
PCW
 8.245
9.402
8.581
 CD1
CD2
CD2
 C48
C48
C48
LEU C:34 C:430 83.0 0.488 H -61.2 -34.1 83.0 0.488 0.0
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 LEU A:34 A:232 51.0 0.3 H -65.4 -33.6 50.0 0.294 0.006 C:P02647:0.006
 PCW
PCW
 9.631
8.409
 CD1
CD2
 C45
C42
LEU C:34 C:430 65.0 0.382 H -67.1 -36.4 64.0 0.376 0.006 A:P02647:0.006
 PCW
 9.792
 CD2
 C28
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 LEU A:34 A:232 72.0 0.424 H -61.5 -39.2 69.0 0.406 0.018 B:P02647:0.018
 PCW
PCW
 6.566
7.627
 CD2
CD2
 C48
C42
LEU B:34 D:430 56.0 0.329 H -58.6 -43.4 56.0 0.329 0.0
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 LEU A:34 A:232 69.0 0.406 H -64.8 -39.1 65.0 0.382 0.024 B:P02647:0.024
 PCW
 5.435
 CD1
 C48
LEU B:34 D:430 63.0 0.371 H -60.2 -34.3 63.0 0.371 0.0 PCW
 7.894
 CD2
 C48
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 LEU C:34 D:275 101.0 0.594 H -63.9 -42.3 37.0 0.218 0.376 D:P02647:0.376
 17F
 7.518
 H
 C1Z
LEU D:34 E:575 47.0 0.276 H -62.4 -46.5 16.0 0.094 0.182 C:P02647:0.182
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 LEU C:34 D:275 88.0 0.518 H -63.5 -46.9 30.0 0.176 0.342 D:P02647:0.341
 17F
7Q9
7Q9
 6.818
9.370
7.873
 H
O
CD2
 C31
C316
C316
LEU D:34 E:575 54.0 0.318 H -65.2 -42.8 17.0 0.1 0.218 C:P02647:0.218
7kjr 2 P02647 100.0 8e-133 EM
 2020-11-18 LEU C:42 C:43 69.0 0.406 H -62.6 -38.9 52.0 0.306 0.1 A:P0DTC3:0.1
 PEE
HOH
 8.598
8.864
 CD2
CB
 C12
O
LEU D:42 D:43 70.0 0.412 H -64.7 -30.7 53.0 0.312 0.1 B:P0DTC3:0.1
 PEE
HOH
 8.548
8.869
 CD2
CB
 C12
O
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 LEU A:76 A:75 19.0 0.112 H -66.3 -38.1 4.0 0.024 0.088 A:P02647:0.088
6clz 2 P02647 89.57 2e-127 NMR
 2018-12-12 LEU B:21 B:75 90.0 0.529 H -69.7 -43.6 36.0 0.212 0.317 C:P02647:0.318
 PX4
PX4
PX4
PX4
PX4
 2.608
7.582
8.452
6.382
4.446
 HD23
HD13
HB3
HD12
HD12
 H44
H20
H57
H69
H44
LEU C:21 C:75 75.0 0.441 H -70.4 -34.3 44.0 0.259 0.182 B:P02647:0.182
 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 7.132
2.194
4.686
9.837
7.591
8.061
6.367
6.367
 HD23
HD21
HD22
HD13
HD22
O
HD23
HD22
 H72
H71
H71
H43
H20
H59
H53
H50
6cm1 2 P02647 89.57 2e-127 NMR
 2018-12-12 LEU B:21 B:75 92.0 0.541 H -85.3 -28.6 33.0 0.194 0.347 C:P02647:0.347
 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 2.169
7.543
2.170
9.523
6.072
6.217
9.675
5.605
 HD21
HD21
HD13
HD22
HD21
HD13
HD21
HD21
 H55
H44
H72
H10
H24
H68
H70
H36
LEU C:21 C:75 100.0 0.588 H -55.1 -51.5 88.0 0.518 0.07 B:P02647:0.071
 PX4
PX4
PX4
PX4
PX4
PX4
PX4
PX4
 8.019
1.936
7.050
2.584
2.895
8.466
2.725
4.156
 HD13
HD12
HD22
HD23
HD13
HD13
HD23
HD21
 H33
H69
H30
H23
H68
H38
H59
H20
2n5e 1 P02647 88.36 1e-112 NMR
 2016-12-21 LEU A:21 A:75 118.0 0.694 H -61.6 -57.5 111.0 0.653 0.041 B:P02647:0.041
LEU B:21 B:75 119.0 0.7 H -61.5 -57.5 111.0 0.653 0.047 A:P02647:0.047

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 LEU A:99 A:99 59.0 0.347 H -70.8 -35.4