Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 116707099 . C A CCDS8378.1:NM_000039.1:c.229Gtg>Ttg_NP_000030.1:p.77V>L Homo sapiens apolipoprotein A-I (APOA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k2s 1 P02647 100.0 4e-177 SOLUTION SCATTERING
 2010-04-07 VAL A:53 A:53 68.0 0.439 H -59.7 -38.5 58.0 0.374 0.065 B:P02647:0.065
 POV
POV
POV
POV
POV
POV
 5.030
4.790
6.097
9.968
8.567
6.553
 CG2
CG1
CG1
CG1
CG2
CG2
 C214
C28
C25
C24
C218
C211
VAL B:53 B:53 65.0 0.419 H -83.9 -40.7 65.0 0.419 0.0 POV
POV
POV
POV
POV
POV
POV
 8.288
3.793
3.648
6.970
6.789
7.908
8.949
 CG1
CG1
CG1
CG2
CG2
O
CG2
 C217
C215
C316
C37
C218
C39
C315
1av1 1 P02647 100.0 3e-142 X-RAY
 1998-02-04 VAL A:11 A:53 47.0 0.303 H -79.8 -46.1 4.0 0.026 0.277 D:P02647:0.277
VAL B:11 B:53 65.0 0.419 H -69.9 -46.1 12.0 0.077 0.342 C:P02647:0.342
VAL C:11 C:53 47.0 0.303 H -79.9 -46.1 4.0 0.026 0.277 B:P02647:0.277
VAL D:11 D:53 65.0 0.419 H -69.9 -46.1 12.0 0.077 0.342 A:P02647:0.342
4v6m 5 P02647 100.0 3e-142 EM
 2014-07-09 VAL E:10 A0:53 62.0 0.4 H -107.3 -38.9 62.0 0.4 0.0 PEV
 8.042
 C
 C25
VAL F:10 A1:53 41.0 0.265 H -74.4 -29.2 41.0 0.265 0.0 PEV
PEV
 7.752
9.346
 C
O
 C44
C14
6pts 1 P02647 100.0 2e-140 NMR
 2020-05-13 VAL A:10 A:210 77.0 0.497 H -73.1 -37.1 77.0 0.497 0.0 PCW
PCW
 6.251
3.836
 CG1
CG1
 C14
C27
VAL B:10 C:408 56.0 0.361 H -61.6 -42.6 55.0 0.355 0.006 A:P02647:0.006
 17F
PCW
PCW
 5.752
9.368
7.702
 CG2
CG1
CG1
 C30
C44
C26
6ptw 1 P02647 100.0 2e-140 NMR
 2020-05-13 VAL A:10 A:210 68.0 0.439 H -68.8 -37.6 68.0 0.439 0.0 PCW
PCW
 7.876
4.857
 CG1
CG1
 C14
C28
VAL B:10 C:408 42.0 0.271 H -62.4 -39.9 42.0 0.271 0.0 17F
PCW
PCW
 5.642
8.604
6.056
 CG2
CG1
CG1
 C30
C44
C26
2msc 1 P02647 100.0 4e-140 NMR
 2015-06-03 VAL A:12 A:210 50.0 0.323 H -79.4 -39.1 50.0 0.323 0.0 PCW
PCW
 6.931
7.238
 CG1
CG1
 C28
C28
VAL B:12 C:408 46.0 0.297 H -65.7 -33.6 46.0 0.297 0.0 17F
PCW
PCW
 8.416
7.159
9.525
 CG2
CG1
CG1
 C30
C47
C25
2msd 1 P02647 100.0 4e-140 NMR
 2015-06-03 VAL A:12 A:210 70.0 0.452 H -75.1 -43.3 70.0 0.452 0.0 PCW
PCW
 8.154
4.452
 O
CG1
 C27
C28
VAL B:12 C:408 52.0 0.335 H -66.4 -37.9 52.0 0.335 0.0 17F
PCW
PCW
 8.566
9.127
6.518
 CG2
CG1
CG1
 C27
C44
C26
2mse 1 P02647 100.0 4e-140 NMR
 2015-06-03 VAL A:12 A:210 49.0 0.316 H -66.1 -49.0 49.0 0.316 0.0 PCW
PCW
 6.937
6.643
 CG1
CG2
 C19
C28
VAL B:12 C:408 49.0 0.316 H -69.9 -38.2 49.0 0.316 0.0 PCW
PCW
 6.059
7.370
 CG1
CG1
 C40
C25
6cc9 1 P02647 100.0 4e-140 NMR
 2018-09-05 VAL A:12 A:210 54.0 0.348 H -80.4 -39.5 54.0 0.348 0.0 PCW
PCW
 9.203
7.293
 CG1
CG1
 C44
C16
VAL C:12 C:408 46.0 0.297 H -64.8 -41.5 46.0 0.297 0.0
6cch 1 P02647 100.0 4e-140 NMR
 2018-08-29 VAL A:12 A:210 50.0 0.323 H -66.2 -48.9 50.0 0.323 0.0 PCW
 7.814
 O
 C16
VAL C:12 C:408 47.0 0.303 H -69.9 -38.1 47.0 0.303 0.0 PCW
PCW
 9.308
9.237
 O
CG1
 C28
C27
6ccx 1 P02647 100.0 4e-140 NMR
 2018-09-05 VAL A:12 A:210 58.0 0.374 H -79.1 -40.1 58.0 0.374 0.0 PCW
PCW
 7.210
8.099
 CG1
CG1
 C16
C28
VAL C:12 C:408 43.0 0.277 H -64.7 -34.3 43.0 0.277 0.0 17F
 9.431
 CG2
 C30
6w4e 1 P02647 100.0 4e-140 NMR
 2020-04-15 VAL A:12 A:210 66.0 0.426 H -70.9 -38.6 66.0 0.426 0.0 PCW
PCW
PCW
 8.556
4.731
9.235
 O
CG1
CG2
 C14
C28
C28
VAL B:12 D:408 51.0 0.329 H -67.4 -37.2 49.0 0.316 0.013 A:P02647:0.013
 17F
PCW
PCW
 6.418
9.962
7.405
 CG1
CG1
CG1
 C29
C44
C26
6w4f 1 P02647 100.0 4e-140 NMR
 2020-04-29 VAL A:12 A:210 73.0 0.471 H -65.8 -44.5 73.0 0.471 0.0 PCW
PCW
PCW
 7.685
5.565
9.725
 CG1
CG1
CG2
 C16
C28
C28
VAL B:12 D:408 57.0 0.368 H -67.1 -37.1 56.0 0.361 0.007 A:P02647:0.006
 PCW
PCW
 9.225
6.655
 CG1
CG1
 C44
C26
7rsc 2 P02647 100.0 4e-140 NMR
 2021-09-22 VAL C:12 NA:NA DO NA DO DO DO NA NA NA
VAL D:12 NA:NA DO NA DO DO DO NA NA NA
7rse 2 P02647 100.0 4e-140 NMR
 2021-09-22 VAL C:12 NA:NA DO NA DO DO DO NA NA NA
VAL D:12 NA:NA DO NA DO DO DO NA NA NA
3r2p 1 P02647 100.0 4e-132 X-RAY
 2011-09-21 VAL A:54 A:53 153.0 0.987 S -65.2 -47.3 153.0 0.987 0.0 HOH
 4.089
 CG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p02647-f1 1 P02647 100.0 0.0 VAL A:77 A:77 77.0 0.497 H -70.0 -42.0