Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 67166470 . C A CCDS8160.1:NM_002708.3:c.688Gag>Tag_NP_002699.1:p.230E>* Homo sapiens protein phosphatase 1 catalytic subunit alpha (PPP1CA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1fjm 1 P08129 100.0 0.0 X-RAY
 1996-06-20 GLU A:230 A:230 74.0 NA H -64.4 -41.2 74.0 NA NA HOH
 3.164
 CB
 O
GLU B:230 B:230 73.0 NA H -70.7 -36.7 NA NA NA
4g9j 1 P62136 100.0 0.0 X-RAY
 2012-09-19 GLU A:231 A:230 57.0 0.3 H -64.2 -45.3 57.0 0.3 0.0
GLU B:231 B:230 114.0 0.6 H -63.3 -45.6 NA NA NA
6g0i 1 P62136 100.0 0.0 X-RAY
 2018-11-21 GLU A:231 A:230 75.0 NA H -72.7 -33.0 75.0 NA NA HOH
 3.156
 N
 O
6g0j 1 P62136 100.0 0.0 X-RAY
 2018-11-21 GLU A:231 A:230 70.0 NA H -63.7 -36.8 70.0 NA NA HOH
 2.879
 CB
 O
5zqv 1 P62137 99.7 0.0 X-RAY
 2019-03-13 GLU A:230 A:230 105.0 0.553 H -70.2 -39.3 105.0 0.553 0.0
GLU B:230 B:230 98.0 0.516 H -69.3 -38.4 NA NA NA
GLU C:230 C:230 129.0 0.679 H -77.5 -22.2 129.0 0.679 0.0
GLU D:230 D:230 122.0 0.642 H -67.8 -34.7 NA NA NA
6dcx 1 P62136 100.0 0.0 X-RAY
 2019-05-15 GLU A:239 A:230 119.0 0.626 H -66.1 -32.7 119.0 0.626 0.0
GLU B:239 B:230 123.0 0.647 H -67.2 -34.7 NA NA NA
6zk6 1 P62136 99.7 0.0 X-RAY
 2020-11-18 GLU A:231 A:230 73.0 NA H -72.6 -31.8 73.0 NA NA HOH
 3.055
 N
 O
3egg 1 P62136 100.0 0.0 X-RAY
 2010-03-23 GLU A:229 A:230 135.0 0.711 H -65.7 -38.5 135.0 0.711 0.0 HOH
 6.829
 N
 O
GLU B:229 B:230 132.0 0.695 H -66.1 -35.4 NA NA NA
3egh 1 P62136 100.0 0.0 X-RAY
 2010-03-23 GLU A:229 A:230 124.0 0.653 H -78.8 -29.3 124.0 0.653 0.0 HOH
 3.794
 CB
 O
GLU B:229 B:230 135.0 0.711 H -66.8 -34.3 NA NA NA
3hvq 1 P62136 100.0 0.0 X-RAY
 2010-03-23 GLU A:229 A:230 68.0 NA H -70.2 -42.1 68.0 NA NA HOH
 2.915
 CG
 O
GLU B:229 B:230 74.0 NA H -68.9 -43.1 74.0 NA NA GOL
HOH
 9.447
2.866
 N
N
 O1
O
6ghm 1 P62136 100.0 0.0 X-RAY
 2019-02-27 GLU A:229 A:230 60.0 NA H -71.0 -36.4 60.0 NA NA EDO
HOH
 7.003
3.227
 O
CB
 C1
O
GLU B:229 B:230 100.0 NA H -67.7 -35.1 NA NA NA
3v4y 1 P62136 100.0 0.0 X-RAY
 2012-10-31 GLU A:229 A:230 86.0 0.453 H -66.0 -37.6 86.0 0.453 0.0 HOH
 2.131
 H
 O
GLU C:229 C:230 93.0 0.489 H -59.9 -44.0 NA NA NA
GLU E:229 E:230 116.0 0.611 H -66.7 -39.1 NA NA NA
GLU G:229 G:230 106.0 0.558 H -66.1 -41.2 NA NA NA
3n5u 1 P62136 100.0 0.0 X-RAY
 2010-08-11 GLU A:230 A:230 56.0 0.295 H -68.1 -47.3 56.0 0.295 0.0
GLU B:230 B:230 53.0 0.279 H -68.4 -47.1 53.0 0.279 0.0
6obn 1 P62136 100.0 0.0 X-RAY
 2019-09-18 GLU A:235 A:230 126.0 0.663 H -65.1 -46.0 126.0 0.663 0.0 HOH
 8.250
 N
 O
GLU B:235 B:230 108.0 0.568 T 64.0 -53.6 NA NA NA
6obp 1 P62136 100.0 0.0 X-RAY
 2019-09-18 GLU A:235 A:230 70.0 NA H -67.6 -24.3 70.0 NA NA
6zej 1 P62136,Q4VY12 100.0 0.0 X-RAY
 2020-09-30 GLU A:229 D:229 42.0 NA H -65.1 -36.9 42.0 NA NA HOH
 5.287
 O
 O
GLU B:229 A:229 52.0 NA H -62.8 -35.4 NA NA NA
GLU C:229 F:229 52.0 NA H -64.9 -36.8 NA NA NA
GLU D:229 I:229 51.0 NA H -57.0 -43.0 NA NA NA
GLU E:229 L:229 53.0 NA H -59.5 -32.4 NA NA NA
GLU F:229 O:229 52.0 NA H -66.8 -33.5 NA NA NA
6zeh 1 P62136,Q13813 100.0 0.0 X-RAY
 2020-09-30 GLU A:229 A:230 130.0 0.684 H -68.5 -33.9 130.0 0.684 0.0 HOH
 2.131
 H
 O
GLU C:229 B:230 140.0 0.737 H -63.8 -37.3 NA NA NA
1it6 1 P36873 90.66 0.0 X-RAY
 2002-05-22 GLU A:230 A:230 64.0 0.337 H -71.6 -33.3 64.0 0.337 0.0 HOH
 9.816
 O
 O
GLU B:230 B:230 131.0 0.689 H -66.0 -24.8 NA NA NA
1jk7 1 P36873 90.66 0.0 X-RAY
 2001-08-15 GLU A:230 A:230 97.0 0.511 H -67.5 -42.7 97.0 0.511 0.0 SO4
HOH
 8.239
2.514
 N
OE1
 O3
O
2bcd 1 P36873 90.66 0.0 X-RAY
 2006-01-17 GLU A:230 A:230 111.0 0.584 H -63.2 -41.6 111.0 0.584 0.0 MN
HOH
 9.171
5.124
 N
O
 MN
O
2bdx 1 P36873 90.66 0.0 X-RAY
 2006-01-17 GLU A:230 A:230 60.0 NA H -70.4 -41.7 60.0 NA NA HOH
 7.042
 O
 O
4ut2 1 P36873 90.66 0.0 X-RAY
 2015-07-22 GLU A:230 A:230 90.0 0.474 H -69.3 -37.2 90.0 0.474 0.0 HOH
 2.759
 OE1
 O
GLU B:230 B:230 100.0 0.526 H -69.0 -37.5 NA NA NA
4ut3 1 P36873 90.66 0.0 X-RAY
 2015-07-22 GLU A:230 A:230 99.0 0.521 H -69.1 -38.1 99.0 0.521 0.0 HOH
 4.990
 N
 O
4ut3 2 P36873 90.66 0.0 X-RAY
 2015-07-22 GLU B:230 B:230 97.0 0.511 H -68.8 -38.3 NA NA NA
4v0u 2 P63087 90.66 0.0 X-RAY
 2015-03-25 GLU D:230 D:230 119.0 0.626 H -72.0 -30.9 NA NA NA
GLU F:230 F:230 117.0 0.616 H -72.0 -31.1 NA NA NA
GLU H:230 H:230 118.0 0.621 H -72.3 -30.7 NA NA NA
GLU J:230 J:230 119.0 0.626 H -72.0 -31.0 119.0 0.626 0.0
GLU N:230 N:230 117.0 0.616 H -72.0 -31.0 NA NA NA
2o8a 1 P63088 90.63 0.0 X-RAY
 2007-07-17 GLU A:236 A:230 122.0 0.642 H -64.5 -32.7 122.0 0.642 0.0 HOH
 2.762
 OE1
 O
GLU C:236 B:230 126.0 0.663 H -62.7 -37.0 NA NA NA
2o8g 1 P63088 90.63 0.0 X-RAY
 2007-07-17 GLU A:236 A:230 130.0 0.684 H -71.1 -29.3 130.0 0.684 0.0 HOH
 2.824
 OE1
 O
GLU C:236 B:230 124.0 0.653 H -65.1 -32.4 NA NA NA
6zeg 1 P62136,Q9UQB8 100.0 0.0 X-RAY
 2020-09-30 GLU A:229 A:230 53.0 NA H -67.2 -33.9 53.0 NA NA HOH
 2.045
 H
 O
GLU C:229 B:230 129.0 0.679 H -64.7 -38.4 NA NA NA
6zei 1 P62136,Q9UQB8 100.0 0.0 X-RAY
 2020-09-30 GLU A:229 A:230 84.0 0.442 H -64.6 -34.8 84.0 0.442 0.0 HOH
 2.226
 HG2
 O
GLU C:229 B:230 89.0 0.468 H -65.8 -39.7 NA NA NA
3e7a 1 P62136 99.66 0.0 X-RAY
 2008-11-04 GLU A:229 A:230 69.0 NA H -65.7 -34.2 69.0 NA NA IOD
HOH
 4.735
3.018
 N
N
 I
O
GLU B:229 B:230 93.0 NA H -68.3 -33.9 NA NA NA
3e7b 1 P62136 99.66 0.0 X-RAY
 2008-11-04 GLU A:229 A:230 145.0 0.763 H -76.0 -29.0 145.0 0.763 0.0 CL
HOH
 3.317
3.147
 N
OE2
 CL
O
GLU B:229 B:230 56.0 NA H -65.6 -40.7 NA NA NA
4mov 1 P62136 99.66 0.0 X-RAY
 2014-03-26 GLU A:229 A:230 147.0 0.774 H -72.9 -27.7 147.0 0.774 0.0 CL
HOH
 3.201
3.181
 N
OE2
 CL
O
GLU B:229 B:230 78.0 NA H -70.4 -32.9 NA NA NA
4moy 1 P62136 99.66 0.0 X-RAY
 2014-03-26 GLU A:229 A:230 75.0 NA H -62.6 -40.3 75.0 NA NA CL
HOH
 3.276
4.191
 N
N
 CL
O
4mp0 1 P62136 99.66 0.0 X-RAY
 2014-03-26 GLU A:229 A:230 57.0 NA H -65.0 -39.2 57.0 NA NA HOH
 3.151
 N
 O
GLU B:229 C:230 66.0 NA H -64.3 -38.8 NA NA NA
4xpn 1 P62136 99.66 0.0 X-RAY
 2015-07-01 GLU A:229 A:230 114.0 0.6 H -61.8 -43.6 114.0 0.6 0.0 HOH
 6.407
 N
 O
GLU C:229 C:230 69.0 NA H -63.7 -41.6 NA NA NA
5ioh 1 P62136 99.66 0.0 X-RAY
 2016-10-05 GLU A:229 A:230 86.0 NA H -65.5 -38.1 86.0 NA NA HOH
 3.162
 N
 O
GLU C:229 C:230 82.0 NA H -64.9 -39.9 NA NA NA
6alz 1 P62136 99.66 0.0 X-RAY
 2017-11-29 GLU A:229 A:230 125.0 0.658 H -73.3 -26.7 125.0 0.658 0.0 CL
HOH
 3.316
2.571
 N
OE2
 CL
O
GLU B:229 B:230 140.0 0.737 H -72.5 -27.5 NA NA NA
6czo 1 P62136 99.66 0.0 X-RAY
 2019-01-23 GLU A:229 A:230 96.0 0.505 H -67.6 -33.6 96.0 0.505 0.0 HOH
 3.185
 N
 O
GLU C:229 C:230 99.0 0.521 H -68.2 -34.5 NA NA NA
6dno 1 P62136 99.66 0.0 X-RAY
 2019-01-23 GLU A:229 A:230 104.0 0.547 H -69.6 -34.0 104.0 0.547 0.0 HOH
 2.856
 N
 O
6zee 1 P62136 99.66 0.0 X-RAY
 2020-09-30 GLU A:229 P:230 101.0 0.532 H -65.1 -33.3 93.0 0.489 0.043 G:Q4VY12:0.042
 HOH
 5.036
 O
 O
GLU B:229 Q:230 106.0 0.558 H -64.4 -31.2 106.0 0.558 0.0 HOH
 2.094
 H
 O
GLU C:229 B:230 48.0 NA H -62.5 -35.4 45.0 NA NA E:P62136:NA
 SO4
HOH
 9.405
1.929
 H
H
 O4
O
GLU D:229 A:230 107.0 0.563 H -63.5 -35.3 95.0 0.5 0.063 J:Q4VY12:0.063
 HOH
 2.135
 H
 O
GLU E:229 I:230 90.0 0.474 H -61.2 -42.6 88.0 0.463 0.011 A:P62136:0.005
 EDO
SO4
GOL
HOH
 9.590
9.084
7.941
1.998
 HG3
H
OE2
H
 H11
O2
HO2
O
GLU F:229 K:230 101.0 0.532 H -59.3 -40.5 101.0 0.532 0.0 EDO
HOH
 8.886
4.300
 N
OE1
 H21
O
6zef 1 P62136 99.66 0.0 X-RAY
 2020-09-30 GLU A:229 A:230 57.0 NA H -73.2 -33.1 57.0 NA NA HOH
 4.202
 HA
 O
GLU B:229 B:230 58.0 NA H -67.8 -26.9 NA NA NA
5zt0 1 P62137 99.66 0.0 X-RAY
 2019-03-13 GLU A:224 A:230 101.0 0.532 H -73.0 -37.4 101.0 0.532 0.0
GLU B:224 B:230 99.0 0.521 H -74.5 -37.1 NA NA NA
GLU C:224 C:230 103.0 0.542 H -79.5 -32.7 NA NA NA
GLU D:224 D:230 98.0 0.516 H -72.2 -39.4 NA NA NA
GLU E:224 E:230 95.0 0.5 H -69.0 -37.0 NA NA NA
GLU F:224 F:230 97.0 0.511 H -72.4 -34.0 NA NA NA
7nzm 2 P62139 99.66 0.0 EM
 2021-09-29 GLU B:224 B:230 140.0 0.737 H -72.7 -28.5 140.0 0.737 0.0
6obq 1 P62136 99.66 0.0 X-RAY
 2019-09-18 GLU A:229 A:230 142.0 0.747 H -72.2 -37.3 142.0 0.747 0.0 HOH
 8.115
 N
 O
GLU B:229 B:230 75.0 NA H -71.6 -37.3 NA NA NA
6obr 1 P62136 99.32 0.0 X-RAY
 2019-09-18 GLU A:229 A:230 144.0 0.758 H -81.7 -29.2 144.0 0.758 0.0 CL
HOH
 3.140
2.738
 N
OE1
 CL
O
GLU B:229 B:230 158.0 0.832 H -80.8 -28.9 NA NA NA
6obs 1 P62136 99.66 0.0 X-RAY
 2019-09-18 GLU A:229 A:230 76.0 NA H -66.9 -34.7 76.0 NA NA HOH
 3.282
 CB
 O
GLU B:229 B:230 82.0 0.432 H -66.8 -35.1 NA NA NA
6obu 1 P62136 99.66 0.0 X-RAY
 2019-09-18 GLU A:229 A:230 147.0 0.774 H -72.6 -30.9 147.0 0.774 0.0 HOH
 3.321
 N
 O
GLU B:229 B:230 64.0 NA H -73.5 -30.3 NA NA NA
1s70 1 P62140 88.79 0.0 X-RAY
 2004-06-22 ASP A:232 A:230 45.0 0.3 H -66.5 -31.1 35.0 0.233 0.067 B:Q90624:0.067
 HOH
 5.319
 N
 O
5inb 1 P36873 97.31 0.0 X-RAY
 2016-10-05 GLU A:227 A:230 108.0 0.568 H -66.3 -35.0 108.0 0.568 0.0 HOH
 2.956
 N
 O
5j28 1 P36873 97.31 0.0 X-RAY
 2016-10-05 GLU A:227 A:230 109.0 0.574 H -66.3 -39.6 109.0 0.574 0.0 HOH
 3.113
 N
 O
GLU B:227 B:230 104.0 0.547 H -62.6 -33.1 NA NA NA
4v0v 1 P63087 97.62 0.0 X-RAY
 2015-03-25 GLU A:225 A:230 121.0 0.637 H -74.1 -28.8 121.0 0.637 0.0 HOH
 2.246
 OE1
 O
GLU C:225 C:230 154.0 0.811 H -70.8 -33.3 NA NA NA
4v0w 1 P63087 97.62 0.0 X-RAY
 2015-03-25 GLU A:225 A:230 95.0 0.5 H -75.4 -31.0 95.0 0.5 0.0 HOH
 2.218
 OE1
 O
GLU C:225 C:230 142.0 0.747 H -75.7 -27.5 NA NA NA
4v0x 1 P63087 97.62 0.0 X-RAY
 2015-03-25 GLU A:225 A:230 107.0 0.563 H -76.0 -27.2 107.0 0.563 0.0 HOH
 2.380
 H
 O
1u32 1 P36873 96.25 0.0 X-RAY
 2004-08-17 GLU A:225 A:230 94.0 0.495 H -65.3 -45.9 94.0 0.495 0.0 HOH
 3.080
 OE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62136-f1 1 P62136 100.0 0.0 GLU A:230 A:230 96.0 0.505 H -64.6 -39.4
af-p36873-f1 1 P36873 90.66 0.0 GLU A:230 A:230 99.0 0.521 H -67.1 -36.6
af-p62140-f1 1 P62140 88.79 0.0 ASP A:229 A:229 40.0 0.267 H -70.0 -32.6