Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85975289 . A C CCDS8273.1:NM_003797.3:c.710gAt>gCt_NP_003788.2:p.237D>A Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 ASP D:237 L:237 49.0 0.327 S -143.6 174.4 3.0 0.02 0.307 C:Q15910:0.04
K:Q15910:0.307
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 ASP E:237 L:237 39.0 0.26 S -141.6 159.1 28.0 0.187 0.073 D:Q15910:0.073
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 ASP C:237 L:237 75.0 0.5 S -154.1 99.5 43.0 0.287 0.213 E:Q15910:0.213
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 ASP B:237 B:237 67.0 0.447 S -155.7 -168.7 41.0 0.273 0.174 A:Q92800:0.173
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 ASP D:237 B:237 66.0 0.44 S -155.4 -169.8 46.0 0.307 0.133 A:Q92800:0.133
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 ASP B:237 B:237 65.0 0.433 S -155.6 -170.5 36.0 0.24 0.193 A:Q92800:0.193
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 ASP B:238 B:237 69.0 0.46 S -124.5 -163.9 69.0 0.46 0.0 A9G
 8.326
 OD1
 C01
ASP D:238 D:237 94.0 0.627 S -142.4 83.1 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 ASP A:198 A:237 56.0 0.373 S -166.2 -179.7 56.0 0.373 0.0 HOH
 2.752
 OD1
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:198 A:237 57.0 0.38 S -165.1 -180.0 57.0 0.38 0.0 HOH
 2.691
 OD2
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:198 A:237 58.0 0.387 S -163.1 180.0 58.0 0.387 0.0 HOH
 2.885
 OD2
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 ASP A:198 A:237 74.0 0.493 S -161.4 -176.9 74.0 0.493 0.0 HOH
 2.576
 OD2
 O
ASP B:198 B:237 74.0 0.493 S -161.7 -176.7 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 ASP A:164 A:237 86.0 0.573 S -143.1 -169.2 86.0 0.573 0.0
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 ASP A:172 A:237 72.0 0.48 S -156.8 179.7 72.0 0.48 0.0 HOH
 2.534
 OD2
 O
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:162 A:237 56.0 0.373 S -172.8 174.7 56.0 0.373 0.0 HOH
 6.426
 O
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:162 A:237 59.0 0.393 S -158.4 179.3 59.0 0.393 0.0 HOH
 2.458
 OD1
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:162 A:237 57.0 0.38 S -158.4 179.7 57.0 0.38 0.0 HOH
 2.587
 OD1
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ASP A:162 A:237 54.0 0.36 S -156.3 176.6 54.0 0.36 0.0 HOH
 2.730
 OD1
 O
ASP B:162 B:237 53.0 0.353 S -153.8 178.0 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ASP A:162 A:237 53.0 0.353 S -151.3 178.8 53.0 0.353 0.0 HOH
 2.724
 OD1
 O
ASP B:162 B:237 54.0 0.36 S -152.4 178.7 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ASP A:162 A:237 54.0 0.36 S -154.1 -179.1 54.0 0.36 0.0 HOH
 2.982
 OD1
 O
ASP B:162 B:237 54.0 0.36 S -153.9 -179.0 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ASP A:162 A:237 54.0 0.36 S -156.7 178.9 54.0 0.36 0.0 HOH
 2.735
 OD1
 O
ASP B:162 B:237 53.0 0.353 S -156.7 179.2 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ASP A:162 A:237 52.0 0.347 S -155.9 177.9 52.0 0.347 0.0 HOH
 2.731
 OD2
 O
ASP B:162 B:237 51.0 0.34 S -154.5 179.8 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ASP A:162 A:237 56.0 0.373 S -145.1 178.6 56.0 0.373 0.0 HOH
 2.730
 OD1
 O
ASP B:162 B:237 56.0 0.373 S -145.3 178.8 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ASP A:162 A:237 53.0 0.353 S -154.7 177.7 53.0 0.353 0.0 HOH
 2.727
 OD2
 O
ASP B:162 B:237 55.0 0.367 S -157.2 179.8 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 ASP A:163 A:237 56.0 0.373 S -130.6 177.1 56.0 0.373 0.0 HOH
 3.083
 OD1
 O
ASP B:163 B:237 52.0 0.347 S -144.4 -178.4 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:163 A:237 53.0 0.353 S -150.0 -177.3 53.0 0.353 0.0 HOH
 2.790
 OD2
 O
ASP B:163 B:237 59.0 0.393 S -155.8 177.6 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:163 A:237 58.0 0.387 S -151.3 173.7 58.0 0.387 0.0 LQD
HOH
 7.941
2.737
 OD1
OD2
 C20
O
ASP B:163 B:237 56.0 0.373 S -149.7 177.8 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:163 A:237 61.0 0.407 S -139.0 -178.0 61.0 0.407 0.0 LQE
HOH
 8.247
2.789
 OD1
OD2
 C17
O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:163 A:237 51.0 0.34 S -155.5 -178.5 51.0 0.34 0.0 HOH
 2.753
 OD2
 O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:163 A:237 45.0 0.3 S -156.7 176.5 45.0 0.3 0.0 HOH
 3.404
 OD2
 O
ASP B:163 B:237 54.0 0.36 S -147.2 174.5 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:163 A:237 47.0 0.313 S -149.3 176.2 47.0 0.313 0.0
ASP B:163 B:237 51.0 0.34 S -142.1 -177.1 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:163 A:237 57.0 0.38 S -156.1 -175.1 57.0 0.38 0.0 HOH
 2.566
 OD1
 O
ASP C:163 C:237 55.0 0.367 S -156.2 -176.2 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:163 A:237 63.0 0.42 S -154.8 -176.1 63.0 0.42 0.0 7VV
HOH
 7.436
2.716
 OD1
OD1
 H44
O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:163 A:237 53.0 0.353 S -154.1 179.2 53.0 0.353 0.0 7VY
HOH
 9.965
3.276
 OD1
OD2
 N12
O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:163 A:237 58.0 0.387 S -158.4 178.7 58.0 0.387 0.0 7W7
HOH
 8.767
2.633
 OD1
OD2
 N19
O
ASP B:163 B:237 56.0 0.373 S -154.7 178.3 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:163 A:237 57.0 0.38 S -155.1 -179.1 57.0 0.38 0.0 7WD
HOH
 8.329
2.728
 OD1
OD2
 N20
O
ASP B:163 B:237 54.0 0.36 S -154.9 179.6 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 ASP A:163 A:237 48.0 0.32 S -151.1 -174.4 48.0 0.32 0.0 HOH
 2.706
 OD2
 O
ASP B:163 B:237 54.0 0.36 S -150.7 -177.8 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ASP A:163 A:237 55.0 0.367 S -154.4 -173.2 55.0 0.367 0.0 HOH
 2.790
 OD1
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 ASP A:163 A:237 56.0 0.373 S -150.0 -170.9 56.0 0.373 0.0 HOH
 2.538
 OD1
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 ASP B:163 B:237 66.0 0.44 S -132.9 -165.0 10.0 0.067 0.373 A:Q15910:0.373
ASP G:163 G:237 70.0 0.467 S -132.7 -166.1 NA NA NA
ASP L:163 L:237 70.0 0.467 S -136.4 -168.3 NA NA NA
ASP Q:163 R:237 66.0 0.44 S -138.1 -169.1 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 ASP B:163 B:237 74.0 0.493 S -133.4 -153.1 14.0 0.093 0.4 A:Q15910:0.4
 74D
 3.622
 OD2
 FBI
ASP E:163 E:237 73.0 0.487 S -139.7 -163.6 NA NA NA
ASP H:163 H:237 61.0 0.407 S -154.2 -160.8 NA NA NA
ASP K:163 K:237 65.0 0.433 S -140.0 -162.0 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:165 A:237 56.0 0.373 S -156.6 -177.9 56.0 0.373 0.0 LQD
HOH
 7.859
2.747
 OD1
OD1
 C21
O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:165 A:237 53.0 0.353 S -158.2 -177.3 53.0 0.353 0.0 7XG
HOH
 7.801
2.848
 OD1
OD2
 C22
O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:165 A:237 56.0 0.373 S -154.5 -175.8 56.0 0.373 0.0 82D
HOH
 7.888
2.692
 OD1
OD1
 C28
O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:165 A:237 57.0 0.38 S -156.2 -178.5 57.0 0.38 0.0 82G
HOH
 7.934
2.712
 OD1
OD2
 C23
O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 ASP A:161 A:237 59.0 0.393 S -152.8 -178.1 59.0 0.393 0.0 HOH
 2.597
 OD1
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:168 A:237 53.0 0.353 S -157.2 -175.0 53.0 0.353 0.0 6PU
HOH
 7.996
2.592
 OD1
OD1
 C1
O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 ASP A:162 A:237 64.0 0.427 S -153.6 172.6 64.0 0.427 0.0 GOL
HOH
 7.197
3.332
 OD1
OD1
 O3
O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 ASP D:162 D:237 52.0 0.347 S -158.7 -172.8 52.0 0.347 0.0
ASP E:162 E:237 54.0 0.36 S -142.6 -171.4 54.0 0.36 0.0
ASP F:162 F:237 49.0 0.327 S -153.6 -172.3 49.0 0.327 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ASP A:164 A:237 53.0 0.353 S -163.5 -178.6 53.0 0.353 0.0 HOH
 2.727
 OD2
 O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ASP A:164 A:237 53.0 0.353 S -155.3 179.8 53.0 0.353 0.0 Q3A
HOH
 7.780
2.666
 O
OD1
 O2
O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ASP A:164 A:237 50.0 0.333 S -155.8 178.6 50.0 0.333 0.0 HOH
 2.706
 OD1
 O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ASP A:164 A:237 55.0 0.367 S -154.6 -179.4 55.0 0.367 0.0 HOH
 3.268
 OD1
 O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:161 A:237 59.0 0.393 S -167.4 177.7 59.0 0.393 0.0 HOH
 2.898
 OD2
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:161 A:237 57.0 0.38 S -161.2 -173.7 57.0 0.38 0.0 HOH
 2.673
 OD2
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:161 A:237 59.0 0.393 S -155.7 -179.5 59.0 0.393 0.0 HOH
 2.523
 OD1
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:161 A:237 53.0 0.353 S -156.3 -177.5 53.0 0.353 0.0 HOH
 2.939
 OD2
 O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 ASP A:157 A:236 52.0 0.347 S -151.3 177.8 52.0 0.347 0.0 HOH
 2.608
 OD2
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ASP C:158 E:223 64.0 0.427 S -151.3 -178.1 NA NA NA
ASP D:158 F:223 66.0 0.44 S -154.2 179.7 58.0 0.387 0.053 A:G1KPH4:0.053
 CJD
 6.587
 OD2
 O28
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ASP C:158 E:223 59.0 0.393 S -141.3 180.0 47.0 0.313 0.08 A:G1KPH4+Q15910:0.08
 6BN
HOH
 3.394
6.124
 OD2
O
 C34
O
ASP D:158 F:223 59.0 0.393 S -141.2 179.4 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ASP C:158 E:223 67.0 0.447 S -135.5 -178.7 NA NA NA
ASP D:158 F:223 67.0 0.447 S -136.4 -178.6 56.0 0.373 0.074 A:G1KPH4+Q15910:0.073
 6BN
 3.368
 CG
 O35
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ASP C:158 E:223 61.0 0.407 S -152.7 178.0 NA NA NA
ASP D:158 F:223 62.0 0.413 S -162.1 177.3 53.0 0.353 0.06 A:G1KPH4:0.06
 CJG
 6.467
 OD2
 C29
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ASP A:157 A:237 57.0 0.38 S -157.0 -177.4 57.0 0.38 0.0 HOH
 2.600
 OD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 ASP A:237 A:237 68.0 0.453 S -152.7 -178.2