Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 85977233 . G A CCDS8273.1:NM_003797.3:c.835Gat>Aat_NP_003788.2:p.279D>N Homo sapiens embryonic ectoderm development (EED), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6c23 4 O75530 100.0 0.0 EM
 2018-01-24 ASP D:279 L:279 113.0 0.753 T -99.2 37.6 113.0 0.753 0.0
6c24 5 O75530 100.0 0.0 EM
 2018-01-24 ASP E:279 L:279 120.0 0.8 T -107.2 46.7 120.0 0.8 0.0
6wkr 3 O75530 100.0 0.0 EM
 2021-02-03 ASP C:279 L:279 117.0 0.78 S -134.3 104.2 117.0 0.78 0.0
7kso 2 O75530 100.0 0.0 EM
 2021-02-03 ASP B:279 B:279 107.0 0.713 T -86.2 7.7 107.0 0.713 0.0
7ksr 4 O75530 100.0 0.0 EM
 2021-02-03 ASP D:279 B:279 109.0 0.727 T -86.5 12.1 109.0 0.727 0.0
7ktp 2 O75530 100.0 0.0 EM
 2021-02-03 ASP B:279 B:279 109.0 0.727 T -84.3 7.7 109.0 0.727 0.0
5wg6 2 O75530 100.0 0.0 X-RAY
 2018-06-27 ASP B:280 B:279 127.0 0.847 S -79.5 28.9 127.0 0.847 0.0
ASP D:280 D:279 106.0 0.707 T -85.1 -13.3 NA NA NA
3jpx 1 O75530 100.0 0.0 X-RAY
 2009-10-20 ASP A:240 A:279 103.0 0.687 T -82.3 -3.3 103.0 0.687 0.0 HOH
 2.650
 OD2
 O
3jzg 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:240 A:279 98.0 0.653 H -88.7 -11.0 98.0 0.653 0.0 HOH
 2.236
 OD1
 O
3jzh 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:240 A:279 104.0 0.693 T -83.4 -0.8 104.0 0.693 0.0 HOH
 2.324
 CB
 O
7kxt 1 O75530 100.0 0.0 X-RAY
 2021-02-24 ASP A:240 A:279 121.0 0.807 H -79.5 -1.8 121.0 0.807 0.0 UNX
HOH
 9.982
9.952
 CB
N
 UNK
O
ASP B:240 B:279 128.0 0.853 H -81.3 -2.0 NA NA NA
5wp3 1 O75530 100.0 0.0 X-RAY
 2017-09-13 ASP A:206 A:279 126.0 0.84 H -77.4 -15.9 126.0 0.84 0.0
5h13 1 O75530 99.19 0.0 X-RAY
 2017-01-25 ASP A:214 A:279 130.0 0.867 T -99.9 1.1 130.0 0.867 0.0
3jzn 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:204 A:279 112.0 0.747 S -77.9 -4.7 112.0 0.747 0.0 HOH
 3.248
 O
 O
3k26 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:204 A:279 101.0 0.673 T -84.0 -6.6 101.0 0.673 0.0 HOH
 2.339
 CB
 O
3k27 1 O75530 100.0 0.0 X-RAY
 2009-12-15 ASP A:204 A:279 95.0 0.633 T -83.5 -2.9 95.0 0.633 0.0 HOH
 2.375
 OD1
 O
6sfb 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ASP A:204 A:279 105.0 0.7 H -84.3 -18.4 105.0 0.7 0.0 HOH
 2.726
 OD1
 O
ASP B:204 B:279 176.0 1.0 -84.2 360.0 NA NA NA
6sfc 1 O75530 100.0 0.0 X-RAY
 2019-09-25 ASP A:204 A:279 104.0 0.693 H -88.9 -12.5 104.0 0.693 0.0 HOH
 2.668
 OD1
 O
ASP B:204 B:279 174.0 1.0 -89.7 360.0 NA NA NA
6yvi 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ASP A:204 A:279 111.0 0.74 S -91.1 -4.7 111.0 0.74 0.0 HOH
 3.218
 OD2
 O
ASP B:204 B:279 176.0 1.0 -91.0 360.0 NA NA NA
6yvj 1 O75530 100.0 0.0 X-RAY
 2021-05-12 ASP A:204 A:279 105.0 0.7 H -87.4 -19.6 105.0 0.7 0.0 HOH
 2.719
 OD1
 O
ASP B:204 B:279 178.0 1.0 -87.7 360.0 NA NA NA
7p3c 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ASP A:204 A:279 103.0 0.687 H -85.4 -17.7 103.0 0.687 0.0 HOH
 2.694
 OD1
 O
ASP B:204 B:279 176.0 1.0 -85.9 360.0 NA NA NA
7p3g 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ASP A:204 A:279 101.0 0.673 S -97.6 -7.3 101.0 0.673 0.0 HOH
 4.111
 C
 O
ASP B:204 B:279 171.0 1.0 -99.4 360.0 NA NA NA
7p3j 1 O75530 100.0 0.0 X-RAY
 2021-12-08 ASP A:204 A:279 106.0 0.707 H -88.2 -17.3 106.0 0.707 0.0 HOH
 2.706
 OD1
 O
ASP B:204 B:279 177.0 1.0 -89.4 360.0 NA NA NA
5gsa 1 O75530 100.0 0.0 X-RAY
 2017-02-01 ASP A:205 A:279 119.0 0.793 H -85.7 -23.3 119.0 0.793 0.0
ASP B:205 B:279 104.0 0.693 H -75.7 -15.4 NA NA NA
5h14 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:205 A:279 108.0 0.72 H -75.6 -18.2 108.0 0.72 0.0 HOH
 3.265
 OD1
 O
ASP B:205 B:279 130.0 0.867 H -79.8 -18.2 NA NA NA
5h15 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:205 A:279 119.0 0.793 H -84.6 -23.3 119.0 0.793 0.0 HOH
 4.852
 OD2
 O
ASP B:205 B:279 104.0 0.693 H -71.4 -15.0 NA NA NA
5h17 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:205 A:279 117.0 0.78 H -64.2 -30.4 117.0 0.78 0.0 HOH
 5.127
 OD2
 O
5h19 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:205 A:279 94.0 0.627 H -68.7 -24.2 94.0 0.627 0.0 HOH
 4.029
 CB
 O
5h24 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:205 A:279 111.0 0.74 H -79.0 -20.9 111.0 0.74 0.0
ASP B:205 B:279 109.0 0.727 H -76.6 -31.5 NA NA NA
5h25 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:205 A:279 97.0 0.647 H -85.2 -12.9 97.0 0.647 0.0
ASP B:205 B:279 113.0 0.753 H -66.7 -28.0 NA NA NA
5ttw 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:205 A:279 104.0 0.693 H -70.5 -4.4 104.0 0.693 0.0 HOH
 2.957
 OD1
 O
ASP C:205 C:279 98.0 0.653 H -79.8 -19.7 NA NA NA
5u5h 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:205 A:279 95.0 0.633 H -83.3 -5.6 95.0 0.633 0.0 HOH
 2.707
 OD2
 O
5u5k 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:205 A:279 115.0 0.767 T -88.3 5.1 115.0 0.767 0.0 HOH
 4.063
 C
 O
5u5t 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:205 A:279 136.0 0.907 H -78.5 -16.9 136.0 0.907 0.0 HOH
 3.431
 OD2
 O
ASP B:205 B:279 135.0 0.9 H -76.7 -16.8 NA NA NA
5u62 1 O75530 100.0 0.0 X-RAY
 2017-01-11 ASP A:205 A:279 136.0 0.907 H -83.0 -16.4 136.0 0.907 0.0 HOH
 3.534
 CB
 O
ASP B:205 B:279 130.0 0.867 H -75.9 -16.2 NA NA NA
6lo2 1 O75530 100.0 0.0 X-RAY
 2021-07-07 ASP A:205 A:279 104.0 0.693 H -80.9 -5.1 104.0 0.693 0.0 HOH
 6.640
 OD1
 O
ASP B:205 B:279 130.0 0.867 T -93.6 -17.6 NA NA NA
6v3x 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ASP A:205 A:279 113.0 0.753 H -81.2 -4.5 113.0 0.753 0.0 HOH
 3.144
 O
 O
4x3e 1 O75530 100.0 0.0 X-RAY
 2015-01-21 ASP A:205 A:279 99.0 0.66 T -83.3 7.0 99.0 0.66 0.0 HOH
 2.336
 OD1
 O
5hyn 2 O75530 100.0 0.0 X-RAY
 2016-05-11 ASP B:205 B:279 117.0 0.78 H -69.2 -17.2 117.0 0.78 0.0
ASP G:205 G:279 120.0 0.8 H -68.8 -18.4 NA NA NA
ASP L:205 L:279 110.0 0.733 H -73.7 -18.7 NA NA NA
ASP Q:205 R:279 103.0 0.687 H -72.4 -22.0 NA NA NA
5ls6 2 O75530 100.0 0.0 X-RAY
 2017-02-22 ASP B:205 B:279 119.0 0.793 H -62.4 -20.9 119.0 0.793 0.0
ASP E:205 E:279 112.0 0.747 H -58.3 -22.1 NA NA NA
ASP H:205 H:279 104.0 0.693 H -69.4 -21.4 NA NA NA
ASP K:205 K:279 110.0 0.733 H -73.2 -11.8 NA NA NA
5u69 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:207 A:279 104.0 0.693 H -85.5 -3.6 104.0 0.693 0.0 HOH
 2.639
 OD1
 O
5u6d 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:207 A:279 102.0 0.68 H -83.2 -3.5 102.0 0.68 0.0 HOH
 3.204
 O
 O
5u8a 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:207 A:279 103.0 0.687 H -84.2 -4.7 103.0 0.687 0.0 HOH
 2.657
 OD1
 O
5u8f 1 O75530 100.0 0.0 X-RAY
 2017-03-15 ASP A:207 A:279 95.0 0.633 H -82.7 -5.0 95.0 0.633 0.0 HOH
 2.686
 OD1
 O
3iiw 1 O75530 100.0 0.0 X-RAY
 2009-09-15 ASP A:203 A:279 106.0 0.707 H -81.9 -5.9 106.0 0.707 0.0 HOH
 2.469
 OD1
 O
5k0m 1 O75530 100.0 0.0 X-RAY
 2017-01-25 ASP A:210 A:279 108.0 0.72 H -85.6 -6.3 108.0 0.72 0.0 HOH
 2.918
 O
 O
5wuk 1 O75530 99.73 0.0 X-RAY
 2017-05-03 ASP A:204 A:279 106.0 0.707 H -84.8 -21.4 106.0 0.707 0.0 HOH
 2.790
 OD2
 O
6u4y 2 O75530 100.0 0.0 X-RAY
 2020-07-08 ASP D:204 D:279 103.0 0.687 T -86.8 5.2 103.0 0.687 0.0
ASP E:204 E:279 102.0 0.68 T -80.4 16.4 102.0 0.68 0.0
ASP F:204 F:279 111.0 0.74 H -75.3 -10.3 111.0 0.74 0.0
6w7f 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ASP A:206 A:279 104.0 0.693 H -81.4 -8.3 104.0 0.693 0.0 Q3D
HOH
 6.036
2.775
 OD2
OD2
 O2
O
6w7g 1 O75530 99.73 0.0 X-RAY
 2020-07-08 ASP A:206 A:279 96.0 0.64 H -81.0 -5.7 96.0 0.64 0.0 Q3A
HOH
 5.700
2.653
 OD2
OD2
 O1
O
7msb 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ASP A:206 A:279 103.0 0.687 H -82.9 -3.6 103.0 0.687 0.0 HOH
 2.731
 OD1
 O
7msd 1 O75530 99.73 0.0 X-RAY
 2021-10-20 ASP A:206 A:279 108.0 0.72 H -80.1 -5.5 108.0 0.72 0.0 HOH
 2.752
 OD2
 O
3iiy 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:203 A:279 111.0 0.74 H -78.0 -12.8 111.0 0.74 0.0 HOH
 3.950
 CB
 O
3ij0 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:203 A:279 105.0 0.7 H -85.3 -4.0 105.0 0.7 0.0 HOH
 3.233
 O
 O
3ij1 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:203 A:279 105.0 0.7 H -81.7 -7.4 105.0 0.7 0.0 HOH
 2.687
 OD1
 O
3ijc 1 O75530 99.73 0.0 X-RAY
 2009-09-15 ASP A:203 A:279 105.0 0.7 H -85.9 -2.6 105.0 0.7 0.0 HOH
 2.992
 O
 O
2qxv 1 Q921E6 100.0 0.0 X-RAY
 2007-08-28 ASP A:199 A:278 122.0 0.813 H -82.4 -16.7 122.0 0.813 0.0 HOH
 2.944
 CB
 O
4w2r 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ASP C:200 E:265 125.0 0.833 H -83.3 -29.0 NA NA NA
ASP D:200 F:265 126.0 0.84 H -78.8 -30.1 126.0 0.84 0.0
5ij7 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ASP C:200 E:265 100.0 0.667 H -73.4 -27.1 100.0 0.667 0.0
ASP D:200 F:265 100.0 0.667 H -73.3 -27.3 NA NA NA
5ij8 2 O75530 100.0 0.0 X-RAY
 2016-05-04 ASP C:200 E:265 132.0 0.88 H -74.6 -28.5 NA NA NA
ASP D:200 F:265 133.0 0.887 H -73.8 -30.3 133.0 0.887 0.0
6b3w 2 O75530 100.0 0.0 X-RAY
 2017-12-27 ASP C:200 E:265 116.0 0.773 H -71.4 -36.2 NA NA NA
ASP D:200 F:265 120.0 0.8 H -73.9 -28.6 120.0 0.8 0.0
6v3y 1 O75530 100.0 0.0 X-RAY
 2021-05-26 ASP A:199 A:279 68.0 NA H -86.7 -0.3 68.0 NA NA HOH
 3.777
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75530-f1 1 O75530 100.0 0.0 ASP A:279 A:279 119.0 0.793 H -73.7 -18.8