Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 111612783 | . | T | A | CCDS8348.1:NM_181699.2:c.1783Ata>Tta_NP_859050.1:p.595I>L | Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1b3u | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
1999-04-12 | LEU | A:582 | A:582 | 10.0 | 0.059 | H | -57.1 | -44.1 | 10.0 | 0.059 | 0.0 |
HOH |
3.669 |
CD1 |
O |
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LEU | B:582 | B:582 | 6.0 | 0.035 | H | -46.8 | -39.0 | NA | NA | NA | |||||||||||||
2ie3 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | LEU | A:583 | A:583 | 7.0 | 0.041 | H | -60.0 | -55.5 | 7.0 | 0.041 | 0.0 | ||||||
2ie4 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | LEU | A:583 | A:583 | 9.0 | 0.053 | H | -52.9 | -40.9 | 9.0 | 0.053 | 0.0 | ||||||
2npp | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-12-12 | LEU | A:583 | A:583 | 2.0 | 0.012 | H | -65.7 | -70.8 | NA | NA | NA | ||||||
LEU | D:583 | D:583 | 1.0 | 0.006 | H | -68.2 | -60.8 | 1.0 | 0.006 | 0.0 | |||||||||||||
3k7v | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | LEU | A:583 | A:583 | 7.0 | 0.041 | H | -58.7 | -56.6 | 7.0 | 0.041 | 0.0 | ||||||
3k7w | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | LEU | A:583 | A:583 | 7.0 | 0.041 | H | -63.3 | -54.1 | 7.0 | 0.041 | 0.0 | ||||||
6nts | 1 | P30153 | 86.22 | 0.0 |
EM |
2020-05-06 | LEU | A:583 | A:583 | 48.0 | 0.282 | H | -63.3 | -42.6 | 48.0 | 0.282 | 0.0 | ||||||
7cun | 10 | P30153 | 86.22 | 0.0 |
EM |
2020-11-25 | LEU | J:583 | P:583 | 19.0 | 0.112 | H | -69.6 | -39.7 | 19.0 | 0.112 | 0.0 | ||||||
7k36 | 1 | P30153 | 86.22 | 0.0 |
EM |
2021-03-10 | LEU | A:583 | A:583 | 29.0 | 0.171 | H | -54.9 | -58.5 | 29.0 | 0.171 | 0.0 | ||||||
7pks | 31 | P30153 | 86.22 | 0.0 |
EM |
2021-12-08 | LEU | EA:583 | p:583 | 37.0 | 0.218 | H | -65.6 | -40.7 | 37.0 | 0.218 | 0.0 | ||||||
3fga | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2009-09-22 | LEU | A:582 | A:583 | 14.0 | 0.082 | H | -64.1 | -38.3 | 14.0 | 0.082 | 0.0 | ||||||
2iae | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2006-12-26 | LEU | A:583 | A:583 | 12.0 | 0.071 | H | -67.9 | -31.7 | 12.0 | 0.071 | 0.0 | ||||||
LEU | D:583 | D:583 | 5.0 | 0.029 | H | -89.2 | -13.7 | NA | NA | NA | |||||||||||||
2pf4 | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2007-08-07 | LEU | A:583 | A:583 | 35.0 | 0.206 | H | -59.7 | -35.8 | 35.0 | 0.206 | 0.0 | ||||||
LEU | B:583 | B:583 | 15.0 | 0.088 | H | -44.2 | -51.1 | NA | NA | NA | |||||||||||||
LEU | C:583 | C:583 | 14.0 | 0.082 | H | -64.7 | -31.0 | NA | NA | NA | |||||||||||||
LEU | D:583 | D:583 | 31.0 | 0.182 | H | -153.4 | -17.6 | NA | NA | NA | |||||||||||||
6ef4 | 1 | Q76MZ3 | 85.93 | 0.0 |
X-RAY |
2019-06-26 | LEU | A:584 | A:583 | 26.0 | 0.153 | T | -73.4 | 6.2 | 26.0 | 0.153 | 0.0 | ||||||
6iur | 1 | P30153 | 85.86 | 0.0 |
X-RAY |
2019-12-04 | LEU | A:581 | A:583 | 16.0 | 0.094 | H | -58.8 | -33.3 | 16.0 | 0.094 | 0.0 | ||||||
LEU | B:581 | B:583 | 37.0 | 0.218 | H | -65.5 | -36.8 | 37.0 | 0.218 | 0.0 | |||||||||||||
LEU | E:581 | E:583 | 31.0 | 0.182 | H | -68.0 | -28.9 | NA | NA | NA | |||||||||||||
LEU | F:581 | F:583 | 28.0 | 0.165 | H | -62.9 | -27.1 | NA | NA | NA | |||||||||||||
2nyl | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | LEU | A:576 | A:583 | 4.0 | 0.024 | T | -109.6 | -57.7 | 4.0 | 0.024 | 0.0 | ||||||
LEU | D:576 | D:583 | 6.0 | 0.035 | T | -111.3 | -50.9 | NA | NA | NA | |||||||||||||
2nym | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | LEU | A:576 | A:583 | 3.0 | 0.018 | T | -95.2 | -65.3 | 3.0 | 0.018 | 0.0 | ||||||
LEU | D:576 | D:583 | 4.0 | 0.024 | H | -87.8 | -63.9 | NA | NA | NA | |||||||||||||
4i5l | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | LEU | A:578 | A:583 | 3.0 | 0.018 | H | -55.8 | -45.3 | 3.0 | 0.018 | 0.0 |
HOH |
4.276 |
CD1 |
O |
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LEU | D:578 | D:583 | 9.0 | 0.053 | H | -56.6 | -39.4 | NA | NA | NA | |||||||||||||
4i5n | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | LEU | A:578 | A:583 | 0.0 | 0.0 | H | -49.4 | -56.1 | 0.0 | 0.0 | 0.0 | ||||||
LEU | D:578 | D:583 | 0.0 | 0.0 | H | -45.2 | -48.4 | NA | NA | NA | |||||||||||||
3dw8 | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2008-10-07 | LEU | A:576 | A:583 | 15.0 | 0.088 | T | -90.1 | -39.9 | 15.0 | 0.088 | 0.0 | ||||||
LEU | D:576 | D:583 | 16.0 | 0.094 | T | -83.0 | -45.5 | NA | NA | NA | |||||||||||||
5w0w | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2018-01-17 | LEU | A:579 | A:583 | 4.0 | 0.024 | H | -91.9 | -46.3 | 4.0 | 0.024 | 0.0 | ||||||
LEU | D:579 | D:583 | 1.0 | 0.006 | H | -106.5 | -37.1 | NA | NA | NA | |||||||||||||
LEU | G:579 | G:583 | 5.0 | 0.029 | H | -80.3 | -39.0 | NA | NA | NA | |||||||||||||
LEU | J:579 | J:583 | 65.0 | 0.382 | H | -81.1 | -23.4 | NA | NA | NA | |||||||||||||
2pkg | 1 | P30153 | 86.38 | 0.0 |
X-RAY |
2007-05-15 | LEU | A:574 | A:583 | 9.0 | 0.053 | H | -49.8 | -20.4 | 9.0 | 0.053 | 0.0 | ||||||
LEU | B:574 | B:583 | 5.0 | 0.029 | H | -71.8 | -45.4 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p30154-f1 | 1 | P30154 | 100.0 | 0.0 | ILE | A:595 | A:595 | 30.0 | 0.171 | H | -60.8 | -44.1 | |
af-p30153-f1 | 1 | P30153 | 86.22 | 0.0 | LEU | A:583 | A:583 | 8.0 | 0.047 | H | -60.0 | -42.1 |