Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 111612808 | . | A | C | CCDS8348.1:NM_181699.2:c.1758gaT>gaG_NP_859050.1:p.586D>E | Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1b3u | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
1999-04-12 | ASP | A:573 | A:573 | 82.0 | 0.547 | H | -76.8 | -37.9 | 82.0 | 0.547 | 0.0 |
HOH |
2.514 |
OD1 |
O |
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| ASP | B:573 | B:573 | 84.0 | 0.56 | T | -95.8 | 9.2 | NA | NA | NA | |||||||||||||
| 2ie3 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | ASP | A:574 | A:574 | 84.0 | 0.56 | H | -64.2 | -36.5 | 6.0 | 0.04 | 0.52 |
B:P67775:0.52 |
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| 2ie4 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | ASP | A:574 | A:574 | 80.0 | 0.533 | H | -71.5 | -31.6 | 5.0 | 0.033 | 0.5 |
B:P67775:0.5 |
HOH |
2.734 |
OD1 |
O |
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| 2npp | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-12-12 | ASP | A:574 | A:574 | 85.0 | 0.567 | H | -80.0 | -42.1 | NA | NA | NA | ||||||
| ASP | D:574 | D:574 | 82.0 | 0.547 | H | -77.3 | -49.4 | 5.0 | 0.033 | 0.514 |
F:P67775:0.513 |
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| 3k7v | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | ASP | A:574 | A:574 | 79.0 | 0.527 | H | -66.9 | -34.6 | 5.0 | 0.033 | 0.494 |
B:P67775:0.493 |
SO4 HOH |
8.821 2.670 |
N OD2 |
O4 O |
|
| 3k7w | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | ASP | A:574 | A:574 | 80.0 | 0.533 | H | -71.5 | -34.2 | 5.0 | 0.033 | 0.5 |
B:P67775:0.5 |
SO4 HOH |
8.628 8.447 |
N OD2 |
O4 O |
|
| 6nts | 1 | P30153 | 86.22 | 0.0 |
EM |
2020-05-06 | ASP | A:574 | A:574 | 60.0 | 0.4 | H | -65.6 | -47.4 | 14.0 | 0.093 | 0.307 |
C:P67775:0.307 |
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| 7cun | 10 | P30153 | 86.22 | 0.0 |
EM |
2020-11-25 | ASP | J:574 | P:574 | 100.0 | 0.667 | H | -67.5 | -49.4 | 9.0 | 0.06 | 0.607 |
K:P67775:0.607 |
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| 7k36 | 1 | P30153 | 86.22 | 0.0 |
EM |
2021-03-10 | ASP | A:574 | A:574 | 84.0 | 0.56 | H | -69.9 | -45.8 | 4.0 | 0.027 | 0.533 |
C:P67775:0.533 |
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| 7pks | 31 | P30153 | 86.22 | 0.0 |
EM |
2021-12-08 | ASP | EA:574 | p:574 | 85.0 | 0.567 | H | -67.1 | -37.1 | 4.0 | 0.027 | 0.54 |
FA:P67775:0.54 |
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| 3fga | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2009-09-22 | ASP | A:573 | A:574 | 79.0 | 0.527 | H | -76.0 | -31.9 | 3.0 | 0.02 | 0.507 |
C:P67775:0.507 |
HOH |
7.787 |
OD1 |
O |
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| 2iae | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2006-12-26 | ASP | A:574 | A:574 | 69.0 | 0.46 | S | -99.7 | -37.7 | 5.0 | 0.033 | 0.427 |
C:P67775:0.427 |
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| ASP | D:574 | D:574 | 86.0 | 0.573 | H | -76.7 | -50.1 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2007-08-07 | ASP | A:574 | A:574 | 84.0 | 0.56 | H | -51.3 | -42.1 | 84.0 | 0.56 | 0.0 | ||||||
| ASP | B:574 | B:574 | 92.0 | 0.613 | H | -63.4 | -39.5 | NA | NA | NA | |||||||||||||
| ASP | C:574 | C:574 | 82.0 | 0.547 | T | -82.6 | -11.9 | NA | NA | NA | |||||||||||||
| ASP | D:574 | D:574 | 67.0 | 0.447 | -67.9 | 120.8 | NA | NA | NA | ||||||||||||||
| 6ef4 | 1 | Q76MZ3 | 85.93 | 0.0 |
X-RAY |
2019-06-26 | ASP | A:575 | A:574 | 65.0 | 0.433 | H | -81.1 | -15.5 | 65.0 | 0.433 | 0.0 | ||||||
| 6iur | 1 | P30153 | 85.86 | 0.0 |
X-RAY |
2019-12-04 | ASP | A:572 | A:574 | 86.0 | 0.573 | H | -72.2 | -42.8 | 86.0 | 0.573 | 0.0 | ||||||
| ASP | B:572 | B:574 | 60.0 | 0.4 | H | -61.6 | -45.2 | 60.0 | 0.4 | 0.0 | |||||||||||||
| ASP | E:572 | E:574 | 84.0 | 0.56 | H | -61.9 | -38.1 | NA | NA | NA | |||||||||||||
| ASP | F:572 | F:574 | 93.0 | 0.62 | H | -69.7 | -40.3 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | ASP | A:567 | A:574 | 91.0 | 0.607 | H | -58.8 | -53.2 | 9.0 | 0.06 | 0.547 |
C:P67775:0.547 |
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| ASP | D:567 | D:574 | 83.0 | 0.553 | H | -64.4 | -54.0 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | ASP | A:567 | A:574 | 83.0 | 0.553 | H | -67.2 | -61.2 | 7.0 | 0.047 | 0.506 |
C:P67775:0.507 |
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| ASP | D:567 | D:574 | 79.0 | 0.527 | H | -76.4 | -57.5 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | ASP | A:569 | A:574 | 73.0 | 0.487 | H | -70.7 | -36.1 | 3.0 | 0.02 | 0.467 |
C:P67775:0.467 |
HOH |
2.647 |
OD1 |
O |
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| ASP | D:569 | D:574 | 70.0 | 0.467 | H | -82.1 | -38.7 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | ASP | A:569 | A:574 | 76.0 | 0.507 | H | -74.3 | -33.4 | 4.0 | 0.027 | 0.48 |
C:P67775:0.48 |
HOH |
3.075 |
OD2 |
O |
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| ASP | D:569 | D:574 | 81.0 | 0.54 | H | -72.6 | -39.1 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2008-10-07 | ASP | A:567 | A:574 | 98.0 | 0.653 | H | -66.7 | -13.0 | 7.0 | 0.047 | 0.606 |
C:P67775:0.607 |
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| ASP | D:567 | D:574 | 98.0 | 0.653 | H | -71.0 | 0.3 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2018-01-17 | ASP | A:570 | A:574 | 93.0 | 0.62 | H | -71.7 | -46.0 | 10.0 | 0.067 | 0.553 |
C:P67775:0.553 |
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| ASP | D:570 | D:574 | 103.0 | 0.687 | H | -60.7 | -25.0 | NA | NA | NA | |||||||||||||
| ASP | G:570 | G:574 | 88.0 | 0.587 | H | -67.1 | -28.0 | NA | NA | NA | |||||||||||||
| ASP | J:570 | J:574 | 66.0 | 0.44 | H | -67.5 | -56.5 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 86.38 | 0.0 |
X-RAY |
2007-05-15 | ASP | A:565 | A:574 | 81.0 | 0.54 | H | -51.2 | -49.6 | 81.0 | 0.54 | 0.0 | ||||||
| ASP | B:565 | B:574 | 83.0 | 0.553 | H | -46.6 | -41.2 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30154-f1 | 1 | P30154 | 100.0 | 0.0 | ASP | A:586 | A:586 | 85.0 | 0.567 | H | -68.6 | -39.4 | |
| af-p30153-f1 | 1 | P30153 | 86.22 | 0.0 | ASP | A:574 | A:574 | 77.0 | 0.513 | H | -73.0 | -38.9 | |