Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 111613299 | . | G | A | CCDS8348.1:NM_181699.2:c.1645Cgc>Tgc_NP_859050.1:p.549R>C | Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1b3u | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
1999-04-12 | ARG | A:536 | A:536 | 20.0 | 0.089 | H | -59.3 | -41.7 | 20.0 | 0.089 | 0.0 |
HOH |
4.098 |
CD |
O |
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| ARG | B:536 | B:536 | 33.0 | 0.147 | H | -56.6 | -44.5 | NA | NA | NA | |||||||||||||
| 2ie3 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | ARG | A:537 | A:537 | 22.0 | 0.098 | H | -54.2 | -48.4 | 16.0 | 0.071 | 0.027 |
B:P67775:0.027 |
|||||
| 2ie4 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | ARG | A:537 | A:537 | 16.0 | 0.071 | H | -59.1 | -47.7 | 10.0 | 0.044 | 0.027 |
B:P67775:0.027 |
HOH |
2.808 |
NH2 |
O |
|
| 2npp | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-12-12 | ARG | A:537 | A:537 | 34.0 | 0.151 | H | -56.3 | -49.7 | NA | NA | NA | ||||||
| ARG | D:537 | D:537 | 32.0 | 0.142 | H | -57.3 | -49.0 | 32.0 | 0.142 | 0.0 | |||||||||||||
| 3k7v | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | ARG | A:537 | A:537 | 33.0 | 0.147 | H | -56.0 | -54.0 | 33.0 | 0.147 | 0.0 |
SO4 HOH |
2.636 5.110 |
NH2 NH1 |
O3 O |
||
| 3k7w | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | ARG | A:537 | A:537 | 30.0 | 0.133 | H | -58.7 | -51.0 | 30.0 | 0.133 | 0.0 |
SO4 HOH |
2.582 5.252 |
NH2 NH1 |
O3 O |
||
| 6nts | 1 | P30153 | 86.22 | 0.0 |
EM |
2020-05-06 | ARG | A:537 | A:537 | 44.0 | 0.196 | H | -84.7 | 0.5 | 44.0 | 0.196 | 0.0 | ||||||
| 7cun | 10 | P30153 | 86.22 | 0.0 |
EM |
2020-11-25 | ARG | J:537 | P:537 | 24.0 | 0.107 | H | -68.3 | -42.5 | 24.0 | 0.107 | 0.0 | ||||||
| 7k36 | 1 | P30153 | 86.22 | 0.0 |
EM |
2021-03-10 | ARG | A:537 | A:537 | 31.0 | 0.138 | H | -68.8 | -49.1 | 31.0 | 0.138 | 0.0 | ||||||
| 7pks | 31 | P30153 | 86.22 | 0.0 |
EM |
2021-12-08 | ARG | EA:537 | p:537 | 30.0 | 0.133 | H | -72.5 | -43.6 | 30.0 | 0.133 | 0.0 | ||||||
| 3fga | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2009-09-22 | ARG | A:536 | A:537 | 38.0 | 0.169 | H | -60.9 | -52.4 | 38.0 | 0.169 | 0.0 |
HOH |
9.504 |
NH2 |
O |
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| 2iae | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2006-12-26 | ARG | A:537 | A:537 | 29.0 | 0.129 | H | -67.7 | -46.8 | 29.0 | 0.129 | 0.0 | ||||||
| ARG | D:537 | D:537 | 33.0 | 0.147 | H | -59.9 | -53.8 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2007-08-07 | ARG | A:537 | A:537 | 30.0 | 0.133 | H | -57.9 | -43.8 | 30.0 | 0.133 | 0.0 | ||||||
| ARG | B:537 | B:537 | 35.0 | 0.156 | H | -50.2 | -44.5 | NA | NA | NA | |||||||||||||
| ARG | C:537 | C:537 | 49.0 | 0.218 | H | -56.0 | -50.3 | NA | NA | NA | |||||||||||||
| ARG | D:537 | D:537 | 66.0 | 0.293 | T | -72.3 | -68.1 | NA | NA | NA | |||||||||||||
| 6ef4 | 1 | Q76MZ3 | 85.93 | 0.0 |
X-RAY |
2019-06-26 | ARG | A:538 | A:537 | 34.0 | 0.151 | H | -54.2 | -43.3 | 34.0 | 0.151 | 0.0 | ||||||
| 6iur | 1 | P30153 | 85.86 | 0.0 |
X-RAY |
2019-12-04 | ARG | A:535 | A:537 | 45.0 | 0.2 | H | -66.9 | -50.1 | 45.0 | 0.2 | 0.0 | ||||||
| ARG | B:535 | B:537 | 22.0 | NA | H | -67.5 | -38.0 | 22.0 | NA | NA | |||||||||||||
| ARG | E:535 | E:537 | 35.0 | 0.156 | H | -67.4 | -48.5 | NA | NA | NA | |||||||||||||
| ARG | F:535 | F:537 | 25.0 | 0.111 | H | -64.2 | -50.9 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | ARG | A:530 | A:537 | 24.0 | 0.107 | H | -73.4 | -58.1 | 24.0 | 0.107 | 0.0 | ||||||
| ARG | D:530 | D:537 | 25.0 | 0.111 | H | -81.0 | -56.3 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | ARG | A:530 | A:537 | 26.0 | 0.116 | H | -81.1 | -51.2 | 26.0 | 0.116 | 0.0 | ||||||
| ARG | D:530 | D:537 | 24.0 | 0.107 | H | -82.8 | -51.7 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | ARG | A:532 | A:537 | 38.0 | 0.169 | H | -59.0 | -44.9 | 38.0 | 0.169 | 0.0 |
HOH |
2.618 |
NH2 |
O |
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| ARG | D:532 | D:537 | 17.0 | 0.076 | H | -64.0 | -47.9 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | ARG | A:532 | A:537 | 37.0 | 0.164 | H | -47.7 | -52.2 | 36.0 | 0.16 | 0.004 |
C:P67775:0.004 |
HOH |
4.706 |
CD |
O |
|
| ARG | D:532 | D:537 | 14.0 | 0.062 | H | -59.8 | -45.8 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2008-10-07 | ARG | A:530 | A:537 | 26.0 | 0.116 | H | -79.0 | -43.0 | 26.0 | 0.116 | 0.0 | ||||||
| ARG | D:530 | D:537 | 29.0 | 0.129 | H | -80.9 | -43.7 | NA | NA | NA | |||||||||||||
| 5w0w | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2018-01-17 | ARG | A:533 | A:537 | 37.0 | 0.164 | H | -70.0 | -43.9 | 37.0 | 0.164 | 0.0 | ||||||
| ARG | D:533 | D:537 | 21.0 | 0.093 | H | -59.5 | -59.7 | NA | NA | NA | |||||||||||||
| ARG | G:533 | G:537 | 19.0 | 0.084 | H | -64.3 | -51.8 | NA | NA | NA | |||||||||||||
| ARG | J:533 | J:537 | 29.0 | 0.129 | H | -75.2 | -42.8 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 86.38 | 0.0 |
X-RAY |
2007-05-15 | ARG | A:528 | A:537 | 47.0 | 0.209 | H | -76.9 | -34.7 | 47.0 | 0.209 | 0.0 | ||||||
| ARG | B:528 | B:537 | 44.0 | 0.196 | H | -63.7 | -52.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30154-f1 | 1 | P30154 | 100.0 | 0.0 | ARG | A:549 | A:549 | 39.0 | 0.173 | H | -60.8 | -42.4 | |
| af-p30153-f1 | 1 | P30153 | 86.22 | 0.0 | ARG | A:537 | A:537 | 41.0 | 0.182 | H | -61.1 | -41.1 | |