Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 111624167 | . | C | A | CCDS8348.1:NM_181699.2:c.1164gaG>gaT_NP_859050.1:p.388E>D | Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1b3u | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
1999-04-12 | GLU | A:375 | A:375 | 158.0 | 0.832 | S | -76.7 | -32.3 | 158.0 | 0.832 | 0.0 |
HOH |
2.711 |
O |
O |
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GLU | B:375 | B:375 | 160.0 | 0.842 | S | -80.6 | 74.8 | NA | NA | NA | |||||||||||||
2ie3 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | GLU | A:376 | A:376 | 160.0 | 0.842 | S | -62.4 | -64.3 | 160.0 | 0.842 | 0.0 | ||||||
2ie4 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | GLU | A:376 | A:376 | 147.0 | 0.774 | S | -62.4 | -80.8 | 147.0 | 0.774 | 0.0 | ||||||
2npp | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:376 | A:376 | 144.0 | 0.758 | S | -73.2 | -58.3 | NA | NA | NA | ||||||
GLU | D:376 | D:376 | 145.0 | 0.763 | S | -81.6 | -53.2 | 145.0 | 0.763 | 0.0 | |||||||||||||
3k7v | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | GLU | A:376 | A:376 | 134.0 | 0.705 | S | -70.5 | -60.1 | 134.0 | 0.705 | 0.0 | ||||||
3k7w | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | GLU | A:376 | A:376 | 139.0 | 0.732 | S | -65.9 | -71.7 | 139.0 | 0.732 | 0.0 | ||||||
6nts | 1 | P30153 | 86.22 | 0.0 |
EM |
2020-05-06 | GLU | A:376 | A:376 | 167.0 | 0.879 | S | -79.7 | -13.5 | 167.0 | 0.879 | 0.0 | ||||||
7cun | 10 | P30153 | 86.22 | 0.0 |
EM |
2020-11-25 | GLU | J:376 | P:376 | 164.0 | 0.863 | S | -84.6 | -35.4 | 164.0 | 0.863 | 0.0 | ||||||
7k36 | 1 | P30153 | 86.22 | 0.0 |
EM |
2021-03-10 | GLU | A:376 | A:376 | 64.0 | NA | S | -166.8 | -171.0 | 64.0 | NA | NA | ||||||
7pks | 31 | P30153 | 86.22 | 0.0 |
EM |
2021-12-08 | GLU | EA:376 | p:376 | 92.0 | NA | S | -69.3 | -23.8 | 92.0 | NA | NA | ||||||
3fga | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2009-09-22 | GLU | A:375 | A:376 | 171.0 | 0.9 | S | -74.2 | -31.3 | 171.0 | 0.9 | 0.0 |
HOH |
3.546 |
O |
O |
||
2iae | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2006-12-26 | GLU | A:376 | A:376 | 177.0 | 0.932 | S | -55.4 | -46.7 | 177.0 | 0.932 | 0.0 | ||||||
GLU | D:376 | D:376 | 152.0 | 0.8 | S | -72.1 | -54.6 | NA | NA | NA | |||||||||||||
2pf4 | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2007-08-07 | GLU | A:376 | A:376 | 160.0 | 0.842 | S | -74.1 | -23.8 | 160.0 | 0.842 | 0.0 | ||||||
GLU | B:376 | B:376 | 153.0 | 0.805 | S | -48.9 | -64.7 | NA | NA | NA | |||||||||||||
GLU | C:376 | C:376 | 177.0 | 0.932 | S | -51.4 | -30.1 | NA | NA | NA | |||||||||||||
GLU | D:376 | D:376 | 162.0 | 0.853 | S | -78.5 | -26.3 | NA | NA | NA | |||||||||||||
6ef4 | 1 | Q76MZ3 | 85.93 | 0.0 |
X-RAY |
2019-06-26 | GLU | A:377 | A:376 | 168.0 | 0.884 | S | -55.2 | -62.2 | 168.0 | 0.884 | 0.0 | ||||||
6iur | 1 | P30153 | 85.86 | 0.0 |
X-RAY |
2019-12-04 | GLU | A:374 | A:376 | 130.0 | 0.684 | S | -79.9 | 28.4 | 130.0 | 0.684 | 0.0 | ||||||
GLU | B:374 | B:376 | 132.0 | 0.695 | S | -75.6 | -29.2 | 132.0 | 0.695 | 0.0 | |||||||||||||
GLU | E:374 | E:376 | 130.0 | 0.684 | S | -75.8 | -29.0 | NA | NA | NA | |||||||||||||
GLU | F:374 | F:376 | 163.0 | 0.858 | S | -80.1 | 40.4 | NA | NA | NA | |||||||||||||
2nyl | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:369 | A:376 | 149.0 | 0.784 | S | -39.8 | -73.0 | 149.0 | 0.784 | 0.0 | ||||||
GLU | D:369 | D:376 | 147.0 | 0.774 | S | -52.7 | -70.5 | NA | NA | NA | |||||||||||||
2nym | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:369 | A:376 | 148.0 | 0.779 | S | -71.5 | -45.1 | 148.0 | 0.779 | 0.0 | ||||||
GLU | D:369 | D:376 | 147.0 | 0.774 | S | -77.1 | -41.3 | NA | NA | NA | |||||||||||||
4i5l | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | GLU | A:371 | A:376 | 174.0 | 0.916 | S | -55.6 | -43.4 | 174.0 | 0.916 | 0.0 |
PEG HOH |
3.633 4.422 |
O O |
C4 O |
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GLU | D:371 | D:376 | 138.0 | 0.726 | S | -61.2 | -33.9 | NA | NA | NA | |||||||||||||
4i5n | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | GLU | A:371 | A:376 | 177.0 | 0.932 | S | -76.6 | -14.2 | 177.0 | 0.932 | 0.0 | ||||||
GLU | D:371 | D:376 | 182.0 | 0.958 | S | -83.7 | -15.9 | NA | NA | NA | |||||||||||||
3dw8 | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2008-10-07 | GLU | A:369 | A:376 | 154.0 | 0.811 | S | -55.0 | -62.8 | 154.0 | 0.811 | 0.0 | ||||||
GLU | D:369 | D:376 | 163.0 | 0.858 | S | -45.0 | -72.8 | NA | NA | NA | |||||||||||||
5w0w | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2018-01-17 | GLU | A:372 | A:376 | 151.0 | 0.795 | S | -68.0 | -42.2 | 151.0 | 0.795 | 0.0 | ||||||
GLU | D:372 | D:376 | 162.0 | 0.853 | S | -60.9 | -39.1 | NA | NA | NA | |||||||||||||
GLU | G:372 | G:376 | 147.0 | 0.774 | S | -60.6 | -67.0 | NA | NA | NA | |||||||||||||
GLU | J:372 | J:376 | 161.0 | 0.847 | S | -92.1 | -64.6 | NA | NA | NA | |||||||||||||
2pkg | 1 | P30153 | 86.38 | 0.0 |
X-RAY |
2007-05-15 | GLU | A:367 | A:376 | 184.0 | 0.968 | S | -77.9 | -5.6 | 184.0 | 0.968 | 0.0 | ||||||
GLU | B:367 | B:376 | 186.0 | 0.979 | S | -88.9 | 9.1 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p30154-f1 | 1 | P30154 | 100.0 | 0.0 | GLU | A:388 | A:388 | 183.0 | 0.963 | S | -65.1 | -32.8 | |
af-p30153-f1 | 1 | P30153 | 86.22 | 0.0 | GLU | A:376 | A:376 | 176.0 | 0.926 | S | -63.5 | -29.1 |