Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 111625741 | . | T | A | CCDS8348.1:NM_181699.2:c.921gaA>gaT_NP_859050.1:p.307E>D | Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1b3u | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
1999-04-12 | GLU | A:294 | A:294 | 73.0 | 0.384 | S | -95.7 | 131.5 | 73.0 | 0.384 | 0.0 |
HOH |
2.669 |
OE1 |
O |
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| GLU | B:294 | B:294 | 68.0 | 0.358 | S | -103.4 | 119.7 | NA | NA | NA | |||||||||||||
| 2ie3 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | GLU | A:295 | A:295 | 74.0 | 0.389 | S | -85.2 | 119.5 | 74.0 | 0.389 | 0.0 | ||||||
| 2ie4 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | GLU | A:295 | A:295 | 75.0 | 0.395 | S | -76.1 | 124.5 | 75.0 | 0.395 | 0.0 | ||||||
| 2npp | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:295 | A:295 | 82.0 | 0.432 | -94.8 | 116.5 | NA | NA | NA | |||||||
| GLU | D:295 | D:295 | 77.0 | 0.405 | -94.7 | 114.8 | 50.0 | 0.263 | 0.142 |
E:Q13362:0.142 |
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| 3k7v | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | GLU | A:295 | A:295 | 80.0 | 0.421 | S | -76.5 | 125.7 | 80.0 | 0.421 | 0.0 | ||||||
| 3k7w | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | GLU | A:295 | A:295 | 82.0 | 0.432 | S | -80.3 | 121.3 | 82.0 | 0.432 | 0.0 | ||||||
| 6nts | 1 | P30153 | 86.22 | 0.0 |
EM |
2020-05-06 | GLU | A:295 | A:295 | 64.0 | 0.337 | -65.1 | 163.7 | 13.0 | 0.068 | 0.269 |
B:Q15172:0.268 |
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| 7cun | 10 | P30153 | 86.22 | 0.0 |
EM |
2020-11-25 | GLU | J:295 | P:295 | 48.0 | 0.253 | -76.6 | 137.5 | 48.0 | 0.253 | 0.0 | |||||||
| 7k36 | 1 | P30153 | 86.22 | 0.0 |
EM |
2021-03-10 | GLU | A:295 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 7pks | 31 | P30153 | 86.22 | 0.0 |
EM |
2021-12-08 | GLU | EA:295 | p:295 | 41.0 | 0.216 | S | -145.6 | 152.6 | 37.0 | 0.195 | 0.021 |
Z:Q9UL03:0.021 |
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| 3fga | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2009-09-22 | GLU | A:294 | A:295 | 60.0 | 0.316 | S | -97.2 | 120.9 | 36.0 | 0.189 | 0.127 |
B:Q13362:0.126 |
HOH |
5.487 |
CB |
O |
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| 2iae | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2006-12-26 | GLU | A:295 | A:295 | 87.0 | 0.458 | S | -78.9 | 126.9 | 57.0 | 0.3 | 0.158 |
B:Q13362:0.158 |
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| GLU | D:295 | D:295 | 86.0 | 0.453 | S | -97.5 | 130.3 | NA | NA | NA | |||||||||||||
| 2pf4 | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2007-08-07 | GLU | A:295 | A:295 | 74.0 | 0.389 | S | -77.3 | 128.0 | 74.0 | 0.389 | 0.0 | ||||||
| GLU | B:295 | B:295 | 71.0 | 0.374 | S | -103.1 | 122.6 | NA | NA | NA | |||||||||||||
| GLU | C:295 | C:295 | 75.0 | 0.395 | S | -119.2 | 119.8 | NA | NA | NA | |||||||||||||
| GLU | D:295 | D:295 | 86.0 | 0.453 | S | -82.8 | 119.3 | NA | NA | NA | |||||||||||||
| 6ef4 | 1 | Q76MZ3 | 85.93 | 0.0 |
X-RAY |
2019-06-26 | GLU | A:296 | A:295 | 74.0 | 0.389 | S | -98.0 | 127.1 | 74.0 | 0.389 | 0.0 | ||||||
| 6iur | 1 | P30153 | 85.86 | 0.0 |
X-RAY |
2019-12-04 | GLU | A:293 | A:295 | 73.0 | 0.384 | S | -67.2 | 137.0 | 73.0 | 0.384 | 0.0 | ||||||
| GLU | B:293 | B:295 | 73.0 | 0.384 | S | -96.8 | 142.3 | 73.0 | 0.384 | 0.0 | |||||||||||||
| GLU | E:293 | E:295 | 58.0 | 0.305 | S | -93.8 | 143.9 | NA | NA | NA | |||||||||||||
| GLU | F:293 | F:295 | 71.0 | 0.374 | S | -70.0 | 137.5 | NA | NA | NA | |||||||||||||
| 2nyl | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:288 | A:295 | 71.0 | 0.374 | S | -104.9 | 110.9 | 43.0 | 0.226 | 0.148 |
B:Q13362:0.147 |
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| GLU | D:288 | D:295 | 66.0 | 0.347 | S | -101.3 | 117.9 | NA | NA | NA | |||||||||||||
| 2nym | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:288 | A:295 | 66.0 | 0.347 | S | -105.2 | 116.5 | 41.0 | 0.216 | 0.131 |
B:Q13362:0.132 |
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| GLU | D:288 | D:295 | 61.0 | 0.321 | S | -100.6 | 129.0 | NA | NA | NA | |||||||||||||
| 4i5l | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | GLU | A:290 | A:295 | 68.0 | 0.358 | S | -100.8 | 124.5 | 68.0 | 0.358 | 0.0 |
HOH |
2.876 |
OE2 |
O |
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| GLU | D:290 | D:295 | 72.0 | 0.379 | S | -99.8 | 127.5 | NA | NA | NA | |||||||||||||
| 4i5n | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | GLU | A:290 | A:295 | 69.0 | 0.363 | S | -99.8 | 125.4 | 69.0 | 0.363 | 0.0 |
HOH |
4.912 |
N |
O |
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| GLU | D:290 | D:295 | 78.0 | 0.411 | S | -78.0 | 127.9 | NA | NA | NA | |||||||||||||
| 3dw8 | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2008-10-07 | GLU | A:288 | A:295 | 63.0 | 0.332 | S | -75.4 | 109.2 | 24.0 | 0.126 | 0.206 |
B:P63151:0.205 |
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| GLU | D:288 | D:295 | 60.0 | 0.316 | -77.5 | 106.7 | NA | NA | NA | ||||||||||||||
| 5w0w | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2018-01-17 | GLU | A:291 | A:295 | 94.0 | 0.495 | S | -66.6 | 130.7 | 94.0 | 0.495 | 0.0 | ||||||
| GLU | D:291 | D:295 | 100.0 | 0.526 | S | -69.4 | 99.8 | NA | NA | NA | |||||||||||||
| GLU | G:291 | G:295 | 71.0 | 0.374 | S | -96.7 | 138.0 | NA | NA | NA | |||||||||||||
| GLU | J:291 | J:295 | 81.0 | 0.426 | S | -117.6 | -174.2 | NA | NA | NA | |||||||||||||
| 2pkg | 1 | P30153 | 86.38 | 0.0 |
X-RAY |
2007-05-15 | GLU | A:286 | A:295 | 91.0 | 0.479 | S | -84.8 | 115.6 | 91.0 | 0.479 | 0.0 | ||||||
| GLU | B:286 | B:295 | 84.0 | 0.442 | S | -83.8 | 122.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p30154-f1 | 1 | P30154 | 100.0 | 0.0 | GLU | A:307 | A:307 | 69.0 | 0.363 | S | -89.2 | 130.7 | |
| af-p30153-f1 | 1 | P30153 | 86.22 | 0.0 | GLU | A:295 | A:295 | 72.0 | 0.379 | S | -88.8 | 131.8 | |