Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 111626103 | . | C | A | CCDS8348.1:NM_181699.2:c.759gaG>gaT_NP_859050.1:p.253E>D | Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1b3u | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
1999-04-12 | GLU | A:240 | A:240 | 88.0 | 0.463 | H | -51.2 | -40.4 | 88.0 | 0.463 | 0.0 |
HOH |
2.923 |
N |
O |
||
GLU | B:240 | B:240 | 83.0 | 0.437 | H | -61.6 | -35.2 | NA | NA | NA | |||||||||||||
2ie3 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | GLU | A:241 | A:241 | 82.0 | 0.432 | H | -53.0 | -38.6 | 82.0 | 0.432 | 0.0 | ||||||
2ie4 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | GLU | A:241 | A:241 | 86.0 | 0.453 | H | -59.7 | -36.5 | 86.0 | 0.453 | 0.0 |
HOH |
8.144 |
N |
O |
||
2npp | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:241 | A:241 | 90.0 | 0.474 | H | -67.5 | -23.5 | NA | NA | NA | ||||||
GLU | D:241 | D:241 | 88.0 | 0.463 | H | -72.0 | -24.0 | 88.0 | 0.463 | 0.0 | |||||||||||||
3k7v | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | GLU | A:241 | A:241 | 83.0 | 0.437 | H | -56.4 | -35.3 | 83.0 | 0.437 | 0.0 |
HOH |
8.400 |
O |
O |
||
3k7w | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | GLU | A:241 | A:241 | 83.0 | 0.437 | H | -61.3 | -31.6 | 83.0 | 0.437 | 0.0 | ||||||
6nts | 1 | P30153 | 86.22 | 0.0 |
EM |
2020-05-06 | GLU | A:241 | A:241 | 101.0 | 0.532 | H | -62.8 | -13.1 | 101.0 | 0.532 | 0.0 | ||||||
7cun | 10 | P30153 | 86.22 | 0.0 |
EM |
2020-11-25 | GLU | J:241 | P:241 | 96.0 | 0.505 | T | -69.6 | 0.5 | 96.0 | 0.505 | 0.0 | ||||||
7k36 | 1 | P30153 | 86.22 | 0.0 |
EM |
2021-03-10 | GLU | A:241 | A:241 | 70.0 | NA | H | -61.9 | -45.5 | 70.0 | NA | NA | ||||||
7pks | 31 | P30153 | 86.22 | 0.0 |
EM |
2021-12-08 | GLU | EA:241 | p:241 | 86.0 | 0.453 | H | -72.3 | -17.0 | 86.0 | 0.453 | 0.0 | ||||||
3fga | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2009-09-22 | GLU | A:240 | A:241 | 80.0 | 0.421 | H | -62.3 | -40.2 | 80.0 | 0.421 | 0.0 | ||||||
2iae | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2006-12-26 | GLU | A:241 | A:241 | 91.0 | 0.479 | T | -64.3 | -25.3 | 91.0 | 0.479 | 0.0 | ||||||
GLU | D:241 | D:241 | 86.0 | 0.453 | H | -55.3 | -16.7 | NA | NA | NA | |||||||||||||
2pf4 | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2007-08-07 | GLU | A:241 | A:241 | 113.0 | 0.595 | H | -61.5 | -32.2 | 113.0 | 0.595 | 0.0 | ||||||
GLU | B:241 | B:241 | 96.0 | 0.505 | H | -76.7 | -42.4 | NA | NA | NA | |||||||||||||
GLU | C:241 | C:241 | 72.0 | 0.379 | I | -66.7 | -36.3 | NA | NA | NA | |||||||||||||
GLU | D:241 | D:241 | 81.0 | 0.426 | H | -60.4 | -41.3 | NA | NA | NA | |||||||||||||
6ef4 | 1 | Q76MZ3 | 85.93 | 0.0 |
X-RAY |
2019-06-26 | GLU | A:242 | A:241 | 100.0 | 0.526 | H | -56.1 | -30.3 | 100.0 | 0.526 | 0.0 | ||||||
6iur | 1 | P30153 | 85.86 | 0.0 |
X-RAY |
2019-12-04 | GLU | A:239 | A:241 | 83.0 | 0.437 | H | -61.2 | -61.5 | 83.0 | 0.437 | 0.0 | ||||||
GLU | B:239 | B:241 | 79.0 | 0.416 | H | -61.8 | -46.1 | 79.0 | 0.416 | 0.0 | |||||||||||||
GLU | E:239 | E:241 | 78.0 | 0.411 | H | -68.0 | -30.1 | NA | NA | NA | |||||||||||||
GLU | F:239 | F:241 | 89.0 | 0.468 | H | -58.9 | -28.5 | NA | NA | NA | |||||||||||||
2nyl | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:234 | A:241 | 92.0 | 0.484 | T | -63.0 | -16.6 | 92.0 | 0.484 | 0.0 | ||||||
GLU | D:234 | D:241 | 85.0 | 0.447 | H | -58.9 | -10.9 | NA | NA | NA | |||||||||||||
2nym | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | GLU | A:234 | A:241 | 87.0 | 0.458 | I | -78.3 | -5.5 | 87.0 | 0.458 | 0.0 | ||||||
GLU | D:234 | D:241 | 87.0 | 0.458 | I | -79.4 | 7.3 | NA | NA | NA | |||||||||||||
4i5l | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | GLU | A:236 | A:241 | 73.0 | 0.384 | H | -62.2 | -37.9 | 73.0 | 0.384 | 0.0 |
HOH |
6.601 |
O |
O |
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GLU | D:236 | D:241 | 76.0 | 0.4 | H | -61.5 | -37.0 | NA | NA | NA | |||||||||||||
4i5n | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | GLU | A:236 | A:241 | 80.0 | 0.421 | H | -32.0 | -50.5 | 80.0 | 0.421 | 0.0 | ||||||
GLU | D:236 | D:241 | 73.0 | 0.384 | H | -64.2 | -33.7 | NA | NA | NA | |||||||||||||
3dw8 | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2008-10-07 | GLU | A:234 | A:241 | 86.0 | 0.453 | H | -30.2 | -25.1 | 86.0 | 0.453 | 0.0 | ||||||
GLU | D:234 | D:241 | 74.0 | 0.389 | H | -38.6 | -31.0 | NA | NA | NA | |||||||||||||
5w0w | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2018-01-17 | GLU | A:237 | A:241 | 78.0 | 0.411 | H | -64.4 | -19.7 | 78.0 | 0.411 | 0.0 | ||||||
GLU | D:237 | D:241 | 71.0 | 0.374 | H | -67.5 | -20.3 | NA | NA | NA | |||||||||||||
GLU | G:237 | G:241 | 60.0 | 0.316 | H | -64.8 | -21.4 | NA | NA | NA | |||||||||||||
GLU | J:237 | J:241 | 81.0 | 0.426 | H | -67.3 | -11.3 | NA | NA | NA | |||||||||||||
2pkg | 1 | P30153 | 86.38 | 0.0 |
X-RAY |
2007-05-15 | GLU | A:232 | A:241 | 77.0 | 0.405 | T | -59.7 | -28.1 | 77.0 | 0.405 | 0.0 | ||||||
GLU | B:232 | B:241 | 91.0 | 0.479 | H | -60.4 | -28.0 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p30154-f1 | 1 | P30154 | 100.0 | 0.0 | GLU | A:253 | A:253 | 71.0 | 0.374 | I | -62.3 | -39.6 | |
af-p30153-f1 | 1 | P30153 | 86.22 | 0.0 | GLU | A:241 | A:241 | 73.0 | 0.384 | H | -58.0 | -35.6 |