Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 111626168 | . | C | A | CCDS8348.1:NM_181699.2:c.694Gtg>Ttg_NP_859050.1:p.232V>L | Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1b3u | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
1999-04-12 | VAL | A:219 | A:219 | 0.0 | 0.0 | H | -88.9 | -46.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.981 |
N |
O |
||
VAL | B:219 | B:219 | 0.0 | 0.0 | H | -91.4 | -51.3 | NA | NA | NA | |||||||||||||
2ie3 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -84.6 | -44.9 | 0.0 | 0.0 | 0.0 | ||||||
2ie4 | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-11-07 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -87.5 | -37.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.853 |
N |
O |
||
2npp | 1 | Q96DH3 | 86.22 | 0.0 |
X-RAY |
2006-12-12 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -100.4 | -41.4 | NA | NA | NA | ||||||
VAL | D:220 | D:220 | 0.0 | 0.0 | H | -106.0 | -45.4 | 0.0 | 0.0 | 0.0 | |||||||||||||
3k7v | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -87.4 | -38.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.732 |
N |
O |
||
3k7w | 1 | P30153 | 86.22 | 0.0 |
X-RAY |
2009-11-03 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -82.3 | -44.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.109 |
N |
O |
||
6nts | 1 | P30153 | 86.22 | 0.0 |
EM |
2020-05-06 | VAL | A:220 | A:220 | 1.0 | 0.006 | H | -62.0 | -40.7 | 1.0 | 0.006 | 0.0 | ||||||
7cun | 10 | P30153 | 86.22 | 0.0 |
EM |
2020-11-25 | VAL | J:220 | P:220 | 6.0 | 0.039 | T | -78.7 | -28.1 | 6.0 | 0.039 | 0.0 | ||||||
7k36 | 1 | P30153 | 86.22 | 0.0 |
EM |
2021-03-10 | VAL | A:220 | A:220 | 25.0 | NA | H | -63.1 | -39.1 | 25.0 | NA | NA | ||||||
7pks | 31 | P30153 | 86.22 | 0.0 |
EM |
2021-12-08 | VAL | EA:220 | p:220 | 0.0 | 0.0 | H | -69.6 | -38.7 | 0.0 | 0.0 | 0.0 | ||||||
3fga | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2009-09-22 | VAL | A:219 | A:220 | 0.0 | 0.0 | H | -75.0 | -49.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.120 |
CG1 |
O |
||
2iae | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2006-12-26 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -111.2 | -43.9 | 0.0 | 0.0 | 0.0 | ||||||
VAL | D:220 | D:220 | 0.0 | 0.0 | H | -94.7 | -42.2 | NA | NA | NA | |||||||||||||
2pf4 | 1 | Q76MZ3 | 86.22 | 0.0 |
X-RAY |
2007-08-07 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -82.1 | -54.4 | 0.0 | 0.0 | 0.0 | ||||||
VAL | B:220 | B:220 | 0.0 | 0.0 | H | -94.4 | -50.9 | NA | NA | NA | |||||||||||||
VAL | C:220 | C:220 | 0.0 | 0.0 | H | -83.0 | -59.7 | NA | NA | NA | |||||||||||||
VAL | D:220 | D:220 | 0.0 | 0.0 | H | -97.1 | -50.5 | NA | NA | NA | |||||||||||||
6ef4 | 1 | Q76MZ3 | 85.93 | 0.0 |
X-RAY |
2019-06-26 | VAL | A:221 | A:220 | 0.0 | 0.0 | H | -87.3 | -51.0 | 0.0 | 0.0 | 0.0 | ||||||
6iur | 1 | P30153 | 85.86 | 0.0 |
X-RAY |
2019-12-04 | VAL | A:218 | A:220 | 0.0 | 0.0 | H | -67.8 | -38.6 | 0.0 | 0.0 | 0.0 | ||||||
VAL | B:218 | B:220 | 0.0 | 0.0 | H | -84.5 | -39.1 | 0.0 | 0.0 | 0.0 | |||||||||||||
VAL | E:218 | E:220 | 0.0 | 0.0 | H | -85.0 | -42.6 | NA | NA | NA | |||||||||||||
VAL | F:218 | F:220 | 0.0 | 0.0 | H | -68.8 | -40.7 | NA | NA | NA | |||||||||||||
2nyl | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | VAL | A:213 | A:220 | 0.0 | 0.0 | H | -107.7 | -56.7 | 0.0 | 0.0 | 0.0 | ||||||
VAL | D:213 | D:220 | 0.0 | 0.0 | H | -121.9 | -43.5 | NA | NA | NA | |||||||||||||
2nym | 1 | Q96DH3 | 86.43 | 0.0 |
X-RAY |
2006-12-12 | VAL | A:213 | A:220 | 0.0 | 0.0 | H | -95.0 | -63.3 | 0.0 | 0.0 | 0.0 | ||||||
VAL | D:213 | D:220 | 0.0 | 0.0 | H | -113.8 | -55.2 | NA | NA | NA | |||||||||||||
4i5l | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | VAL | A:215 | A:220 | 1.0 | 0.006 | H | -82.1 | -46.4 | 1.0 | 0.006 | 0.0 |
PEG HOH |
9.692 4.716 |
C N |
C3 O |
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VAL | D:215 | D:220 | 1.0 | 0.006 | H | -76.6 | -46.1 | NA | NA | NA | |||||||||||||
4i5n | 1 | P30153 | 86.13 | 0.0 |
X-RAY |
2013-05-08 | VAL | A:215 | A:220 | 0.0 | 0.0 | H | -82.5 | -42.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.806 |
N |
O |
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VAL | D:215 | D:220 | 1.0 | 0.006 | H | -71.3 | -44.6 | NA | NA | NA | |||||||||||||
3dw8 | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2008-10-07 | VAL | A:213 | A:220 | 0.0 | 0.0 | H | -74.0 | -43.5 | 0.0 | 0.0 | 0.0 | ||||||
VAL | D:213 | D:220 | 0.0 | 0.0 | H | -81.6 | -52.7 | NA | NA | NA | |||||||||||||
5w0w | 1 | P30153 | 86.4 | 0.0 |
X-RAY |
2018-01-17 | VAL | A:216 | A:220 | 0.0 | 0.0 | H | -77.3 | -33.1 | 0.0 | 0.0 | 0.0 | ||||||
VAL | D:216 | D:220 | 0.0 | 0.0 | H | -90.3 | -27.1 | NA | NA | NA | |||||||||||||
VAL | G:216 | G:220 | 0.0 | 0.0 | H | -87.6 | -36.6 | NA | NA | NA | |||||||||||||
VAL | J:216 | J:220 | 0.0 | 0.0 | H | -76.7 | -28.1 | NA | NA | NA | |||||||||||||
2pkg | 1 | P30153 | 86.38 | 0.0 |
X-RAY |
2007-05-15 | VAL | A:211 | A:220 | 0.0 | 0.0 | H | -115.8 | -41.8 | 0.0 | 0.0 | 0.0 | ||||||
VAL | B:211 | B:220 | 0.0 | 0.0 | H | -97.5 | -57.0 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p30154-f1 | 1 | P30154 | 100.0 | 0.0 | VAL | A:232 | A:232 | 0.0 | 0.0 | H | -85.4 | -48.4 | |
af-p30153-f1 | 1 | P30153 | 86.22 | 0.0 | VAL | A:220 | A:220 | 0.0 | 0.0 | H | -89.0 | -49.5 |