Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 111631629 . A C CCDS8348.1:NM_181699.2:c.453gaT>gaG_NP_859050.1:p.151D>E Homo sapiens protein phosphatase 2 scaffold subunit Abeta (PPP2R1B), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b3u 1 P30153 86.22 0.0 X-RAY
 1999-04-12 ASP A:138 A:138 163.0 1.0 S -77.5 -33.9 163.0 1.0 0.0 HOH
 2.619
 O
 O
ASP B:138 B:138 166.0 1.0 S -76.7 -25.6 NA NA NA
2ie3 1 Q96DH3 86.22 0.0 X-RAY
 2006-11-07 ASP A:139 A:139 148.0 0.987 S -79.7 -79.6 148.0 0.987 0.0
2ie4 1 Q96DH3 86.22 0.0 X-RAY
 2006-11-07 ASP A:139 A:139 152.0 1.0 S -81.5 -77.0 152.0 1.0 0.0
2npp 1 Q96DH3 86.22 0.0 X-RAY
 2006-12-12 ASP A:139 A:139 152.0 1.0 S -78.5 -28.5 NA NA NA
ASP D:139 D:139 150.0 1.0 S -72.7 -31.3 150.0 1.0 0.0
3k7v 1 P30153 86.22 0.0 X-RAY
 2009-11-03 ASP A:139 A:139 151.0 1.0 S -70.9 -85.6 151.0 1.0 0.0
3k7w 1 P30153 86.22 0.0 X-RAY
 2009-11-03 ASP A:139 A:139 144.0 0.96 S -70.0 -89.8 144.0 0.96 0.0
6nts 1 P30153 86.22 0.0 EM
 2020-05-06 ASP A:139 A:139 147.0 0.98 S -71.4 -42.5 145.0 0.967 0.013 B:Q15172:0.013
7cun 10 P30153 86.22 0.0 EM
 2020-11-25 ASP J:139 P:139 137.0 0.913 S -83.3 -40.0 137.0 0.913 0.0
7k36 1 P30153 86.22 0.0 EM
 2021-03-10 ASP A:139 A:139 29.0 NA -79.3 122.3 29.0 NA NA
7pks 31 P30153 86.22 0.0 EM
 2021-12-08 ASP EA:139 p:139 143.0 0.953 S -72.3 -24.4 143.0 0.953 0.0
3fga 1 Q76MZ3 86.22 0.0 X-RAY
 2009-09-22 ASP A:138 A:139 147.0 0.98 S -63.1 -34.6 147.0 0.98 0.0 HOH
 3.853
 O
 O
2iae 1 Q76MZ3 86.22 0.0 X-RAY
 2006-12-26 ASP A:139 A:139 151.0 1.0 S -77.9 -43.0 151.0 1.0 0.0
ASP D:139 D:139 143.0 0.953 S -71.0 -55.6 NA NA NA
2pf4 1 Q76MZ3 86.22 0.0 X-RAY
 2007-08-07 ASP A:139 A:139 149.0 0.993 S -79.0 -25.7 109.0 0.727 0.266 E:Q9W9P1:0.267
ASP B:139 B:139 158.0 1.0 S -73.8 -30.9 NA NA NA
ASP C:139 C:139 142.0 0.947 S -74.2 -42.4 NA NA NA
ASP D:139 D:139 151.0 1.0 S -67.7 -24.9 NA NA NA
6ef4 1 Q76MZ3 85.93 0.0 X-RAY
 2019-06-26 ASP A:140 A:139 164.0 1.0 S -70.1 -54.3 164.0 1.0 0.0
6iur 1 P30153 85.86 0.0 X-RAY
 2019-12-04 ASP A:137 A:139 162.0 1.0 S -71.7 -31.6 162.0 1.0 0.0
ASP B:137 B:139 165.0 1.0 S -63.7 -60.1 165.0 1.0 0.0
ASP E:137 E:139 162.0 1.0 S -64.7 -62.1 NA NA NA
ASP F:137 F:139 167.0 1.0 S -70.1 -31.9 NA NA NA
2nyl 1 Q96DH3 86.43 0.0 X-RAY
 2006-12-12 ASP A:132 A:139 158.0 1.0 S -83.2 -50.2 158.0 1.0 0.0
ASP D:132 D:139 159.0 1.0 S -77.9 -55.7 NA NA NA
2nym 1 Q96DH3 86.43 0.0 X-RAY
 2006-12-12 ASP A:132 A:139 160.0 1.0 S -52.3 -38.3 160.0 1.0 0.0
ASP D:132 D:139 161.0 1.0 S -55.1 -36.3 NA NA NA
4i5l 1 P30153 86.13 0.0 X-RAY
 2013-05-08 ASP A:134 A:139 159.0 1.0 S -68.6 -33.2 99.0 0.66 0.34 B:Q9Y5P8+Q99741:0.4
 PEG
PEG
HOH
 6.167
7.571
3.058
 O
O
O
 O1
O1
O
ASP D:134 D:139 146.0 0.973 S -60.7 -36.4 NA NA NA
4i5n 1 P30153 86.13 0.0 X-RAY
 2013-05-08 ASP A:134 A:139 154.0 1.0 S -72.4 -36.0 96.0 0.64 0.36 B:Q9Y5P8+Q99741:0.387
 HOH
 2.533
 O
 O
ASP D:134 D:139 155.0 1.0 S -69.3 -40.0 NA NA NA
3dw8 1 P30153 86.4 0.0 X-RAY
 2008-10-07 ASP A:132 A:139 156.0 1.0 S -52.9 -40.4 156.0 1.0 0.0
ASP D:132 D:139 150.0 1.0 S -74.5 -24.6 NA NA NA
5w0w 1 P30153 86.4 0.0 X-RAY
 2018-01-17 ASP A:135 A:139 144.0 0.96 S -69.9 -50.4 95.0 0.633 0.327 B:Q8BH58:0.327
ASP D:135 D:139 158.0 1.0 S -73.0 5.3 NA NA NA
ASP G:135 G:139 162.0 1.0 S -81.1 -12.5 NA NA NA
ASP J:135 J:139 158.0 1.0 S -60.0 -49.2 NA NA NA
2pkg 1 P30153 86.38 0.0 X-RAY
 2007-05-15 ASP A:130 A:139 149.0 0.993 S -74.9 -56.4 144.0 0.96 0.033 C:P03081:0.033
ASP B:130 B:139 154.0 1.0 S -60.5 -43.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p30154-f1 1 P30154 100.0 0.0 ASP A:151 A:151 148.0 0.987 S -59.8 -42.7
af-p30153-f1 1 P30153 86.22 0.0 ASP A:139 A:139 154.0 1.0 S -61.1 -38.4