Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 112019447 . C A CCDS44731.1:NM_001562.3:c.239cGg>cTg_NP_001553.1:p.80R>L Homo sapiens interleukin 18 (IL18), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3wo2 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 ARG A:44 A:44 56.0 0.249 H -92.1 -20.7 56.0 0.249 0.0 CPS
CPS
HOH
 5.810
8.628
3.362
 N
C
CG
 O3
C11
O
ARG B:44 B:44 91.0 0.404 H -97.4 -18.2 NA NA NA
ARG C:44 C:44 63.0 0.28 H -93.2 -17.2 NA NA NA
ARG D:44 D:44 63.0 0.28 H -102.1 -2.2 NA NA NA
3wo3 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 ARG A:44 A:44 75.0 0.333 T -54.0 -24.3 62.0 0.276 0.057 B:Q13478:0.058
 SO4
HOH
 9.819
3.875
 C
NE
 O4
O
ARG C:44 C:44 38.0 0.169 T -54.9 -24.9 NA NA NA
ARG E:44 E:44 48.0 0.213 T -55.1 -25.8 NA NA NA
ARG G:44 G:44 46.0 0.204 T -55.2 -24.6 NA NA NA
ARG I:44 I:44 86.0 0.382 T -68.8 -11.9 NA NA NA
ARG K:44 K:44 115.0 0.511 T -52.2 -24.1 NA NA NA
3wo4 1 Q14116 100.0 4e-114 X-RAY
 2014-12-17 ARG A:44 A:44 56.0 0.249 T -59.1 -37.2 40.0 0.178 0.071 B:Q13478:0.071
 HOH
 2.453
 NH2
 O
4xft 1 Q14116 97.45 3e-111 X-RAY
 2015-06-10 ARG A:44 A:44 100.0 0.444 H -99.8 -11.5 100.0 0.444 0.0 HOH
 4.404
 N
 O
ARG B:44 B:44 128.0 0.569 H -96.8 -17.1 NA NA NA
2vxt 2 Q14116 97.45 4e-111 X-RAY
 2009-06-23 ARG B:44 I:80 39.0 0.173 T -74.1 -13.9 39.0 0.173 0.0 HOH
 3.425
 CG
 O
4hjj 1 Q14116 97.44 1e-110 X-RAY
 2013-05-08 ARG A:44 A:80 76.0 0.338 T -93.5 -27.2 76.0 0.338 0.0 HOH
 3.666
 NH2
 O
4xfs 1 Q14116 96.82 1e-110 X-RAY
 2015-06-10 ARG A:44 A:44 62.0 0.276 S -77.1 -10.9 62.0 0.276 0.0 HOH
 5.067
 N
 O
ARG B:44 B:44 33.0 0.147 S -79.0 -8.4 NA NA NA
4r6u 2 Q14116 97.45 2e-110 X-RAY
 2014-10-15 ARG C:44 B:44 66.0 0.293 T -70.1 -18.5 51.0 0.227 0.066 A:Q13478:0.067
ARG D:44 D:44 43.0 0.191 T -69.6 -17.9 NA NA NA
3f62 2 Q14116 97.45 2e-110 X-RAY
 2009-01-06 ARG B:45 B:44 74.0 0.329 G -77.7 -6.4 74.0 0.329 0.0 HOH
 2.830
 NH2
 O
4xfu 1 Q14116 96.18 3e-109 X-RAY
 2015-06-10 ARG A:44 A:44 87.0 0.387 T -109.3 3.4 87.0 0.387 0.0
ARG B:44 B:44 107.0 0.476 T -98.1 -6.5 NA NA NA
4eee 2 Q14116 94.9 2e-101 X-RAY
 2012-09-26 ARG B:44 B:44 96.0 0.427 T -61.8 -37.2 96.0 0.427 0.0 HOH
 3.268
 NH2
 O
ARG D:44 NA:NA DO NA DO DO DO NA NA NA
4ekx 2 Q14116 94.9 2e-101 X-RAY
 2012-09-26 ARG B:44 B:44 146.0 0.649 360.0 -36.1 146.0 0.649 0.0 HOH
 5.822
 O
 O
ARG C:44 D:44 95.0 0.422 T -88.6 -4.3 95.0 0.422 0.0 HOH
 4.177
 CD
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14116-f1 1 Q14116 100.0 2e-142 ARG A:80 A:80 71.0 0.316 T -73.4 -14.2