Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 112019459 | . | T | A | CCDS44731.1:NM_001562.3:c.227gAt>gTt_NP_001553.1:p.76D>V | Homo sapiens interleukin 18 (IL18), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3wo2 | 1 | Q14116 | 100.0 | 4e-114 |
X-RAY |
2014-12-17 | ASP | A:40 | A:40 | 82.0 | NA | H | -69.7 | -28.1 | 82.0 | NA | NA |
CPS CPS HOH |
4.978 6.562 3.481 |
O N CA |
O1 C1 O |
||
| ASP | B:40 | B:40 | 82.0 | NA | H | -71.3 | -23.4 | NA | NA | NA | |||||||||||||
| ASP | C:40 | C:40 | 105.0 | 0.7 | H | -70.8 | -24.0 | NA | NA | NA | |||||||||||||
| ASP | D:40 | D:40 | 82.0 | NA | H | -70.7 | -25.5 | NA | NA | NA | |||||||||||||
| 3wo3 | 1 | Q14116 | 100.0 | 4e-114 |
X-RAY |
2014-12-17 | ASP | A:40 | A:40 | 129.0 | 0.86 | H | -63.7 | -21.7 | 70.0 | 0.467 | 0.393 |
B:Q13478:0.393 |
SO4 HOH |
6.635 6.570 |
N N |
O4 O |
|
| ASP | C:40 | C:40 | 133.0 | 0.887 | H | -65.8 | -20.5 | NA | NA | NA | |||||||||||||
| ASP | E:40 | E:40 | 131.0 | 0.873 | H | -64.4 | -21.3 | NA | NA | NA | |||||||||||||
| ASP | G:40 | G:40 | 132.0 | 0.88 | H | -65.2 | -21.7 | NA | NA | NA | |||||||||||||
| ASP | I:40 | I:40 | 136.0 | 0.907 | T | -76.4 | -27.3 | NA | NA | NA | |||||||||||||
| ASP | K:40 | K:40 | 133.0 | 0.887 | H | -65.5 | -19.7 | NA | NA | NA | |||||||||||||
| 3wo4 | 1 | Q14116 | 100.0 | 4e-114 |
X-RAY |
2014-12-17 | ASP | A:40 | A:40 | 118.0 | 0.787 | H | -63.2 | -28.3 | 61.0 | 0.407 | 0.38 |
B:Q13478:0.38 |
HOH |
8.253 |
O |
O |
|
| 4xft | 1 | Q14116 | 97.45 | 3e-111 |
X-RAY |
2015-06-10 | ASP | A:40 | A:40 | 115.0 | 0.767 | H | -56.6 | -27.1 | 115.0 | 0.767 | 0.0 |
HOH |
4.445 |
CA |
O |
||
| ASP | B:40 | B:40 | 126.0 | 0.84 | H | -58.6 | -26.3 | NA | NA | NA | |||||||||||||
| 2vxt | 2 | Q14116 | 97.45 | 4e-111 |
X-RAY |
2009-06-23 | ASP | B:40 | I:76 | 118.0 | 0.787 | H | -47.8 | -40.5 | 118.0 | 0.787 | 0.0 |
HOH |
2.809 |
OD2 |
O |
||
| 4hjj | 1 | Q14116 | 97.44 | 1e-110 |
X-RAY |
2013-05-08 | ASP | A:40 | A:76 | 137.0 | 0.913 | H | -64.3 | -34.9 | 137.0 | 0.913 | 0.0 |
HOH |
2.693 |
OD1 |
O |
||
| 4xfs | 1 | Q14116 | 96.82 | 1e-110 |
X-RAY |
2015-06-10 | ASP | A:40 | A:40 | 138.0 | 0.92 | H | -71.9 | -21.1 | 138.0 | 0.92 | 0.0 |
HOH |
7.509 |
C |
O |
||
| ASP | B:40 | B:40 | 140.0 | 0.933 | H | -72.1 | -20.5 | NA | NA | NA | |||||||||||||
| 4r6u | 2 | Q14116 | 97.45 | 2e-110 |
X-RAY |
2014-10-15 | ASP | C:40 | B:40 | 122.0 | 0.813 | H | -86.6 | -5.5 | 73.0 | 0.487 | 0.326 |
A:Q13478:0.327 |
|||||
| ASP | D:40 | D:40 | 118.0 | 0.787 | H | -90.6 | -2.0 | NA | NA | NA | |||||||||||||
| 3f62 | 2 | Q14116 | 97.45 | 2e-110 |
X-RAY |
2009-01-06 | ASP | B:41 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4xfu | 1 | Q14116 | 96.18 | 3e-109 |
X-RAY |
2015-06-10 | ASP | A:40 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ASP | B:40 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4eee | 2 | Q14116 | 94.9 | 2e-101 |
X-RAY |
2012-09-26 | ASP | B:40 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ASP | D:40 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4ekx | 2 | Q14116 | 94.9 | 2e-101 |
X-RAY |
2012-09-26 | ASP | B:40 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ASP | C:40 | D:40 | 170.0 | 1.0 | S | -61.8 | -40.2 | 170.0 | 1.0 | 0.0 |
HOH |
2.718 |
OD1 |
O |
|||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q14116-f1 | 1 | Q14116 | 100.0 | 2e-142 | ASP | A:76 | A:76 | 121.0 | 0.807 | H | -68.2 | -29.4 | |