Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 114168684 . G A CCDS8368.1:NM_006169.2:c.166Gga>Aga_NP_006160.1:p.56G>R Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5yjf 1 P40261 98.86 0.0 X-RAY
 2018-03-21 GLY A:76 A:56 24.0 0.32 E 156.7 -170.1 24.0 0.32 0.0 HOH
 8.467
 O
 O
GLY B:76 B:56 17.0 0.227 E 170.7 -164.6 NA NA NA
GLY C:76 C:56 23.0 0.307 E 164.8 -167.2 NA NA NA
GLY D:76 D:56 18.0 0.24 E 157.4 -173.8 NA NA NA
2iip 1 P40261 98.86 0.0 X-RAY
 2006-10-10 GLY A:75 A:56 24.0 0.32 E 158.6 -155.9 24.0 0.32 0.0 HOH
 6.191
 C
 O
GLY B:75 B:56 25.0 0.333 E 155.2 -154.1 NA NA NA
GLY C:75 C:56 20.0 0.267 E 167.6 -164.2 NA NA NA
GLY D:75 D:56 19.0 0.253 E 163.1 -164.3 NA NA NA
3rod 1 P40261 98.86 0.0 X-RAY
 2011-09-07 GLY A:75 A:56 22.0 0.293 E 148.1 174.6 22.0 0.293 0.0 HOH
 5.862
 O
 O
GLY B:75 B:56 19.0 0.253 E 159.3 172.9 NA NA NA
GLY C:75 C:56 13.0 0.173 E 171.9 174.7 NA NA NA
GLY D:75 D:56 9.0 0.12 E -158.7 172.7 NA NA NA
6b1a 1 P40261 98.86 0.0 X-RAY
 2018-01-31 GLY A:75 A:56 12.0 0.16 E 165.9 -163.7 12.0 0.16 0.0 HOH
 7.750
 O
 O
GLY B:75 B:56 20.0 0.267 E 162.0 -164.3 NA NA NA
GLY C:75 C:56 13.0 0.173 E 174.6 -165.2 NA NA NA
GLY D:75 D:56 20.0 0.267 E 168.0 -166.4 NA NA NA
6chh 1 P40261 98.86 0.0 X-RAY
 2018-06-13 GLY A:75 A:56 15.0 0.2 E 167.1 -163.8 15.0 0.2 0.0 HOH
 7.745
 O
 O
GLY B:75 B:56 20.0 0.267 E 161.1 -163.4 NA NA NA
GLY C:75 C:56 13.0 0.173 E 172.6 -165.7 13.0 0.173 0.0 HOH
 4.153
 CA
 O
GLY D:75 D:56 22.0 0.293 E 167.0 -166.3 22.0 0.293 0.0 HOH
 3.607
 CA
 O
6orr 1 Q6FH49 98.86 0.0 X-RAY
 2019-10-23 GLY A:75 A:56 18.0 0.24 E 169.3 -166.0 18.0 0.24 0.0 HOH
 3.516
 O
 O
GLY B:75 B:56 18.0 0.24 E 167.9 -167.2 NA NA NA
GLY C:75 C:56 22.0 0.293 E 166.6 -168.3 NA NA NA
GLY D:75 D:56 21.0 0.28 E 165.1 -168.3 NA NA NA
6pve 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 GLY A:75 A:56 27.0 0.36 E 156.8 -164.2 27.0 0.36 0.0 HOH
 4.602
 CA
 O
GLY B:75 B:56 27.0 0.36 E 158.6 -164.5 NA NA NA
GLY C:75 C:56 26.0 0.347 E 159.2 -163.8 NA NA NA
GLY D:75 D:56 29.0 0.387 E 158.8 -163.6 NA NA NA
6pvs 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 GLY A:75 A:56 29.0 0.387 E 160.2 -153.7 29.0 0.387 0.0 HOH
 5.502
 CA
 O
GLY B:75 B:56 28.0 0.373 E 161.1 -153.4 NA NA NA
GLY C:75 C:56 27.0 0.36 E 160.6 -154.7 NA NA NA
GLY D:75 D:56 24.0 0.32 E 162.6 -154.7 NA NA NA
7bkg 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLY A:75 A:56 13.0 0.173 E 168.9 -160.1 13.0 0.173 0.0 HOH
 3.217
 O
 O
GLY B:75 B:56 19.0 0.253 E 159.9 -167.6 NA NA NA
GLY C:75 C:56 23.0 0.307 E 166.2 -172.2 NA NA NA
GLY D:75 D:56 23.0 0.307 E 170.3 -163.7 NA NA NA
7ble 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLY A:75 A:56 10.0 0.133 E 170.5 -157.9 10.0 0.133 0.0 HOH
 3.870
 CA
 O
GLY B:75 B:56 8.0 0.107 E 161.3 -174.0 NA NA NA
GLY C:75 C:56 20.0 0.267 E 167.6 -160.8 NA NA NA
GLY D:75 D:56 14.0 0.187 E 154.0 173.4 NA NA NA
7nbj 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLY A:75 A:56 16.0 0.213 E 156.0 -172.4 16.0 0.213 0.0 HOH
 5.827
 O
 O
GLY B:75 B:56 19.0 0.253 E 158.2 -168.1 NA NA NA
GLY C:75 C:56 21.0 0.28 E 160.0 -167.0 NA NA NA
GLY D:75 D:56 18.0 0.24 E 162.0 -168.1 NA NA NA
7nbm 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLY A:75 A:56 6.0 0.08 E -179.2 -173.1 6.0 0.08 0.0 HOH
 5.060
 CA
 O
GLY B:75 B:56 3.0 0.04 E 171.8 174.7 NA NA NA
GLY C:75 C:56 22.0 0.293 E 172.1 -165.6 NA NA NA
GLY D:75 D:56 20.0 0.267 E 164.6 -162.3 NA NA NA
7nbq 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLY A:75 A:56 19.0 0.253 E 167.9 -163.9 19.0 0.253 0.0 HOH
 4.896
 CA
 O
GLY B:75 B:56 10.0 0.133 E 158.2 -171.7 NA NA NA
GLY C:75 C:56 19.0 0.253 E 168.6 -176.7 NA NA NA
GLY D:75 D:56 15.0 0.2 E 177.6 -169.8 NA NA NA
7egu 1 P40261 99.61 0.0 X-RAY
 2021-12-15 GLY A:55 A:56 26.0 0.347 E 162.1 -165.1 26.0 0.347 0.0 HOH
 5.930
 O
 O
7ehz 1 P40261 99.61 0.0 X-RAY
 2021-12-15 GLY A:55 A:56 21.0 0.28 E 157.5 -175.8 21.0 0.28 0.0 HOH
 9.786
 O
 O
5xvq 1 F7ERX8 96.97 0.0 X-RAY
 2017-08-02 GLY A:76 A:56 20.0 0.267 E 168.4 -172.9 20.0 0.267 0.0 GOL
HOH
 5.287
5.837
 CA
C
 O1
O
GLY B:76 B:56 21.0 0.28 E 171.1 -164.8 NA NA NA
2i62 1 O55239 85.5 7e-168 X-RAY
 2006-09-12 GLY A:57 A:57 34.0 0.453 E 161.6 -159.4 34.0 0.453 0.0 HOH
 2.725
 O
 O
GLY B:57 B:57 10.0 0.133 E 161.6 -162.0 NA NA NA
GLY C:57 C:57 26.0 0.347 E 148.2 -168.9 NA NA NA
GLY D:57 D:57 24.0 0.32 E 152.4 -159.5 NA NA NA
5xvk 1 O55239 85.5 2e-167 X-RAY
 2017-08-02 GLY A:76 A:56 27.0 0.36 E 164.1 -164.6 27.0 0.36 0.0 HOH
 3.711
 CA
 O
GLY B:76 B:56 31.0 0.413 165.4 -166.7 NA NA NA
5yji 1 O55239 85.5 2e-167 X-RAY
 2018-03-21 GLY A:76 A:56 29.0 0.387 E 163.7 -168.9 29.0 0.387 0.0 HOH
 3.766
 CA
 O
GLY B:76 B:56 33.0 0.44 E 162.7 -161.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p40261-f1 1 P40261 100.0 0.0 GLY A:56 A:56 19.0 0.253 E 179.1 -168.6