Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 114168717 . A C CCDS8368.1:NM_006169.2:c.199Act>Cct_NP_006160.1:p.67T>P Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5yjf 1 P40261 98.86 0.0 X-RAY
 2018-03-21 THR A:87 A:67 0.0 0.0 -100.9 143.7 0.0 0.0 0.0 SAH
8WO
HOH
 3.148
7.433
7.513
 CG2
CG2
CG2
 O
O2
O
THR B:87 B:67 0.0 0.0 -95.8 148.0 NA NA NA
THR C:87 C:67 0.0 0.0 -100.5 153.3 NA NA NA
THR D:87 D:67 0.0 0.0 -104.7 149.4 NA NA NA
2iip 1 P40261 98.86 0.0 X-RAY
 2006-10-10 THR A:86 A:67 0.0 0.0 -112.4 148.0 0.0 0.0 0.0 SAH
HOH
 3.347
4.880
 OG1
CA
 CA
O
THR B:86 B:67 0.0 0.0 -110.0 145.8 NA NA NA
THR C:86 C:67 0.0 0.0 -113.7 148.8 NA NA NA
THR D:86 D:67 0.0 0.0 -106.6 147.6 NA NA NA
3rod 1 P40261 98.86 0.0 X-RAY
 2011-09-07 THR A:86 A:67 0.0 0.0 -110.6 160.9 0.0 0.0 0.0 SAH
NCA
HOH
 3.437
8.024
8.814
 OG1
CG2
CG2
 C
C6
O
THR B:86 B:67 0.0 0.0 -103.3 160.7 NA NA NA
THR C:86 C:67 0.0 0.0 -114.8 168.5 NA NA NA
THR D:86 D:67 0.0 0.0 -113.5 178.7 NA NA NA
6b1a 1 P40261 98.86 0.0 X-RAY
 2018-01-31 THR A:86 A:67 0.0 0.0 -104.8 160.6 0.0 0.0 0.0 C8J
HOH
 3.549
4.707
 CG2
CA
 O
O
THR B:86 B:67 0.0 0.0 -105.8 156.7 NA NA NA
THR C:86 C:67 0.0 0.0 -105.9 153.6 NA NA NA
THR D:86 D:67 0.0 0.0 -105.8 155.4 NA NA NA
6chh 1 P40261 98.86 0.0 X-RAY
 2018-06-13 THR A:86 A:67 0.0 0.0 -103.1 161.4 0.0 0.0 0.0 F0P
HOH
 3.266
4.763
 OG1
CA
 CA
O
THR B:86 B:67 0.0 0.0 -106.8 156.7 NA NA NA
THR C:86 C:67 0.0 0.0 -106.7 154.2 0.0 0.0 0.0 F0P
HOH
 3.300
4.525
 OG1
CA
 CA
O
THR D:86 D:67 0.0 0.0 -105.8 156.5 0.0 0.0 0.0 F0P
HOH
 3.314
4.480
 OG1
CA
 CA
O
6orr 1 Q6FH49 98.86 0.0 X-RAY
 2019-10-23 THR A:86 A:67 5.0 0.036 -102.8 151.4 5.0 0.036 0.0 N37
HOH
 3.596
4.778
 OG1
N
 C15
O
THR B:86 B:67 4.0 0.029 -103.5 151.2 NA NA NA
THR C:86 C:67 3.0 0.021 -103.4 152.8 NA NA NA
THR D:86 D:67 4.0 0.029 -104.2 151.8 NA NA NA
6pve 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 THR A:86 A:67 5.0 0.036 -106.1 151.1 5.0 0.036 0.0 OZP
HOH
 3.426
4.753
 OG1
N
 C20
O
THR B:86 B:67 5.0 0.036 -107.1 151.1 NA NA NA
THR C:86 C:67 5.0 0.036 -107.6 150.7 NA NA NA
THR D:86 D:67 5.0 0.036 -106.8 148.6 NA NA NA
6pvs 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 THR A:86 A:67 6.0 0.043 -106.6 155.3 6.0 0.043 0.0 P0V
HOH
 2.523
4.067
 OG1
CA
 H212
O
THR B:86 B:67 6.0 0.043 -107.4 155.2 NA NA NA
THR C:86 C:67 6.0 0.043 -107.6 152.8 NA NA NA
THR D:86 D:67 6.0 0.043 -106.9 151.0 NA NA NA
7bkg 1 P40261 98.86 0.0 X-RAY
 2021-03-17 THR A:86 A:67 0.0 0.0 -102.5 155.1 0.0 0.0 0.0 SAH
U0Z
HOH
 3.363
7.620
4.773
 OG1
CG2
N
 CA
N12
O
THR B:86 B:67 0.0 0.0 -103.2 155.7 NA NA NA
THR C:86 C:67 0.0 0.0 -106.0 151.2 NA NA NA
THR D:86 D:67 0.0 0.0 -104.4 141.6 NA NA NA
7ble 1 P40261 98.86 0.0 X-RAY
 2021-03-17 THR A:86 A:67 0.0 0.0 -103.6 151.4 0.0 0.0 0.0 SAH
U1W
HOH
 3.252
7.419
5.588
 OG1
CG2
OG1
 CA
C15
O
THR B:86 B:67 0.0 0.0 -107.2 153.3 NA NA NA
THR C:86 C:67 0.0 0.0 -95.6 156.1 NA NA NA
THR D:86 D:67 0.0 0.0 -110.1 153.3 NA NA NA
7nbj 1 P40261 98.86 0.0 X-RAY
 2021-03-17 THR A:86 A:67 3.0 0.021 -105.1 157.2 3.0 0.021 0.0 U7H
HOH
 6.889
3.164
 CG2
OG1
 N14
O
THR B:86 B:67 4.0 0.029 -105.8 153.9 NA NA NA
THR C:86 C:67 5.0 0.036 -106.8 153.4 NA NA NA
THR D:86 D:67 4.0 0.029 -106.2 158.6 NA NA NA
7nbm 1 P40261 98.86 0.0 X-RAY
 2021-03-17 THR A:86 A:67 5.0 0.036 -125.9 152.6 5.0 0.036 0.0 U7K
HOH
 6.601
3.586
 CG2
OG1
 C17
O
THR B:86 B:67 2.0 0.014 -116.8 156.0 NA NA NA
THR C:86 C:67 4.0 0.029 -117.6 147.3 NA NA NA
THR D:86 D:67 4.0 0.029 -94.5 151.2 NA NA NA
7nbq 1 P40261 98.86 0.0 X-RAY
 2021-03-17 THR A:86 A:67 0.0 0.0 -96.0 154.6 0.0 0.0 0.0 SAH
U72
HOH
 3.478
7.550
4.609
 OG1
CG2
N
 CA
C13
O
THR B:86 B:67 0.0 0.0 -102.0 152.9 NA NA NA
THR C:86 C:67 0.0 0.0 -103.9 154.6 NA NA NA
THR D:86 D:67 0.0 0.0 -103.4 154.7 NA NA NA
7egu 1 P40261 99.61 0.0 X-RAY
 2021-12-15 THR A:66 A:67 11.0 0.079 -104.0 154.1 0.0 0.0 0.079 B:None:0.079
 HOH
 5.016
 N
 O
7ehz 1 P40261 99.61 0.0 X-RAY
 2021-12-15 THR A:66 A:67 10.0 0.071 -109.2 152.7 0.0 0.0 0.071 B:None:0.071
 HOH
 4.883
 OG1
 O
5xvq 1 F7ERX8 96.97 0.0 X-RAY
 2017-08-02 THR A:87 A:67 0.0 0.0 -96.6 153.4 0.0 0.0 0.0 SAH
8GC
HOH
 3.286
7.960
4.949
 OG1
CG2
N
 CA
C9
O
THR B:87 B:67 0.0 0.0 -104.1 152.4 NA NA NA
2i62 1 O55239 85.5 7e-168 X-RAY
 2006-09-12 THR A:68 A:68 0.0 0.0 -112.8 149.1 0.0 0.0 0.0 SAH
HOH
 3.637
4.899
 OG1
N
 C
O
THR B:68 B:68 0.0 0.0 -104.0 151.4 NA NA NA
THR C:68 C:68 0.0 0.0 -105.8 151.6 NA NA NA
THR D:68 D:68 0.0 0.0 -104.3 149.2 NA NA NA
5xvk 1 O55239 85.5 2e-167 X-RAY
 2017-08-02 THR A:87 A:67 0.0 0.0 -102.3 152.1 0.0 0.0 0.0 SAH
8GC
HOH
 3.353
7.999
4.938
 OG1
CG2
N
 CA
C9
O
THR B:87 B:67 0.0 0.0 -108.4 149.6 NA NA NA
5yji 1 O55239 85.5 2e-167 X-RAY
 2018-03-21 THR A:87 A:67 0.0 0.0 -103.9 153.4 0.0 0.0 0.0 SAH
8WO
HOH
 3.330
7.598
4.846
 OG1
CG2
N
 CA
O2
O
THR B:87 B:67 0.0 0.0 -108.8 152.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p40261-f1 1 P40261 100.0 0.0 THR A:67 A:67 3.0 0.021 -111.1 150.0