Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 114168766 . T A CCDS8368.1:NM_006169.2:c.248gTc>gAc_NP_006160.1:p.83V>D Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5yjf 1 P40261 98.86 0.0 X-RAY
 2018-03-21 VAL A:103 A:83 0.0 0.0 E -108.7 146.7 0.0 0.0 0.0 SAH
 9.094
 CG1
 N
VAL B:103 B:83 1.0 0.006 E -97.5 137.9 NA NA NA
VAL C:103 C:83 1.0 0.006 E -113.1 138.6 NA NA NA
VAL D:103 D:83 1.0 0.006 E -109.8 137.0 NA NA NA
2iip 1 P40261 98.86 0.0 X-RAY
 2006-10-10 VAL A:102 A:83 1.0 0.006 E -107.7 143.5 1.0 0.006 0.0 SAH
HOH
 8.960
7.611
 CG1
O
 N
O
VAL B:102 B:83 1.0 0.006 E -110.1 146.8 NA NA NA
VAL C:102 C:83 0.0 0.0 E -96.1 142.5 NA NA NA
VAL D:102 D:83 0.0 0.0 E -112.2 139.9 NA NA NA
3rod 1 P40261 98.86 0.0 X-RAY
 2011-09-07 VAL A:102 A:83 3.0 0.019 E -91.4 144.1 3.0 0.019 0.0 SAH
 9.229
 CB
 N
VAL B:102 B:83 2.0 0.013 E -96.3 150.1 NA NA NA
VAL C:102 C:83 0.0 0.0 E -100.3 147.5 NA NA NA
VAL D:102 D:83 0.0 0.0 E -104.2 133.3 NA NA NA
6b1a 1 P40261 98.86 0.0 X-RAY
 2018-01-31 VAL A:102 A:83 3.0 0.019 E -113.3 142.9 3.0 0.019 0.0 C8J
HOH
 8.176
7.448
 CG1
CG1
 N
O
VAL B:102 B:83 3.0 0.019 E -104.0 145.4 NA NA NA
VAL C:102 C:83 1.0 0.006 E -110.3 135.9 NA NA NA
VAL D:102 D:83 1.0 0.006 E -104.7 135.8 NA NA NA
6chh 1 P40261 98.86 0.0 X-RAY
 2018-06-13 VAL A:102 A:83 2.0 0.013 E -110.6 142.7 2.0 0.013 0.0 F0P
HOH
 8.317
7.389
 CG1
CG1
 N
O
VAL B:102 B:83 4.0 0.026 E -105.5 145.0 NA NA NA
VAL C:102 C:83 1.0 0.006 E -110.3 135.9 1.0 0.006 0.0 F0P
HOH
 9.248
7.724
 CB
CA
 N
O
VAL D:102 D:83 1.0 0.006 E -105.3 135.6 1.0 0.006 0.0 F0P
HOH
 9.415
6.830
 CG1
O
 N
O
6orr 1 Q6FH49 98.86 0.0 X-RAY
 2019-10-23 VAL A:102 A:83 4.0 0.026 E -107.3 135.1 4.0 0.026 0.0 N37
HOH
 8.739
7.391
 CG1
CG1
 N6
O
VAL B:102 B:83 1.0 0.006 E -107.2 134.3 NA NA NA
VAL C:102 C:83 4.0 0.026 E -110.5 130.7 NA NA NA
VAL D:102 D:83 0.0 0.0 E -106.9 136.5 NA NA NA
6pve 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 VAL A:102 A:83 1.0 0.006 E -102.0 137.7 1.0 0.006 0.0 OZP
HOH
 9.339
7.394
 CB
O
 N21
O
VAL B:102 B:83 2.0 0.013 E -102.2 138.1 NA NA NA
VAL C:102 C:83 0.0 0.0 E -102.3 137.7 NA NA NA
VAL D:102 D:83 0.0 0.0 E -104.0 138.3 NA NA NA
6pvs 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 VAL A:102 A:83 3.0 0.019 E -99.4 136.3 3.0 0.019 0.0 P0V
HOH
 8.287
9.852
 CB
CG2
 H212
O
VAL B:102 B:83 0.0 0.0 E -97.7 136.2 NA NA NA
VAL C:102 C:83 0.0 0.0 E -99.8 131.0 NA NA NA
VAL D:102 D:83 1.0 0.006 E -101.3 131.2 NA NA NA
7bkg 1 P40261 98.86 0.0 X-RAY
 2021-03-17 VAL A:102 A:83 1.0 0.006 E -105.1 138.2 1.0 0.006 0.0 SAH
HOH
 9.291
7.282
 CB
O
 N
O
VAL B:102 B:83 4.0 0.026 E -101.7 138.3 NA NA NA
VAL C:102 C:83 0.0 0.0 E -102.8 134.4 NA NA NA
VAL D:102 D:83 0.0 0.0 E -108.5 135.5 NA NA NA
7ble 1 P40261 98.86 0.0 X-RAY
 2021-03-17 VAL A:102 A:83 2.0 0.013 E -91.1 135.7 2.0 0.013 0.0 SAH
HOH
 9.333
8.275
 CB
CG1
 N
O
VAL B:102 B:83 3.0 0.019 E -94.3 141.1 NA NA NA
VAL C:102 C:83 0.0 0.0 E -105.3 126.3 NA NA NA
VAL D:102 D:83 2.0 0.013 E -103.1 128.6 NA NA NA
7nbj 1 P40261 98.86 0.0 X-RAY
 2021-03-17 VAL A:102 A:83 4.0 0.026 E -105.1 135.1 4.0 0.026 0.0 U7H
HOH
 9.956
6.458
 C
O
 C32
O
VAL B:102 B:83 4.0 0.026 E -101.9 133.0 NA NA NA
VAL C:102 C:83 1.0 0.006 E -109.5 134.1 NA NA NA
VAL D:102 D:83 0.0 0.0 E -101.3 129.5 NA NA NA
7nbm 1 P40261 98.86 0.0 X-RAY
 2021-03-17 VAL A:102 A:83 1.0 0.006 E -90.1 146.7 1.0 0.006 0.0 U7K
HOH
 9.861
9.151
 C
N
 C30
O
VAL B:102 B:83 1.0 0.006 E -103.7 131.0 NA NA NA
VAL C:102 C:83 2.0 0.013 E -99.7 134.9 NA NA NA
VAL D:102 D:83 6.0 0.039 E -106.6 124.7 NA NA NA
7nbq 1 P40261 98.86 0.0 X-RAY
 2021-03-17 VAL A:102 A:83 1.0 0.006 E -93.0 139.4 1.0 0.006 0.0 SAH
HOH
 9.336
7.688
 CB
O
 N
O
VAL B:102 B:83 4.0 0.026 E -95.4 137.4 NA NA NA
VAL C:102 C:83 0.0 0.0 E -112.9 132.7 NA NA NA
VAL D:102 D:83 0.0 0.0 E -106.5 133.0 NA NA NA
7egu 1 P40261 99.61 0.0 X-RAY
 2021-12-15 VAL A:82 A:83 0.0 0.0 E -102.4 151.6 0.0 0.0 0.0 HOH
 6.803
 O
 O
7ehz 1 P40261 99.61 0.0 X-RAY
 2021-12-15 VAL A:82 A:83 2.0 0.013 E -106.1 143.7 2.0 0.013 0.0 HOH
 6.104
 N
 O
5xvq 1 F7ERX8 96.97 0.0 X-RAY
 2017-08-02 VAL A:103 A:83 0.0 0.0 E -97.5 142.4 0.0 0.0 0.0 SAH
HOH
 9.060
7.099
 CG1
O
 N
O
VAL B:103 B:83 0.0 0.0 E -101.5 141.9 NA NA NA
2i62 1 O55239 85.5 7e-168 X-RAY
 2006-09-12 VAL A:84 A:84 1.0 0.006 E -108.1 146.0 1.0 0.006 0.0 SAH
HOH
 9.166
6.972
 CB
O
 N
O
VAL B:84 B:84 0.0 0.0 E -109.4 149.2 NA NA NA
VAL C:84 C:84 1.0 0.006 E -108.1 147.9 NA NA NA
VAL D:84 D:84 0.0 0.0 E -107.9 145.8 NA NA NA
5xvk 1 O55239 85.5 2e-167 X-RAY
 2017-08-02 VAL A:103 A:83 0.0 0.0 E -105.0 148.2 0.0 0.0 0.0 SAH
HOH
 9.203
6.862
 CB
O
 N
O
VAL B:103 B:83 0.0 0.0 E -103.0 143.0 NA NA NA
5yji 1 O55239 85.5 2e-167 X-RAY
 2018-03-21 VAL A:103 A:83 0.0 0.0 E -105.1 148.2 0.0 0.0 0.0 SAH
HOH
 9.026
6.950
 CB
O
 N
O
VAL B:103 B:83 1.0 0.006 E -100.9 142.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p40261-f1 1 P40261 100.0 0.0 VAL A:83 A:83 2.0 0.013 E -102.3 137.4