Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 114168858 | . | G | A | CCDS8368.1:NM_006169.2:c.340Gtg>Atg_NP_006160.1:p.114V>M | Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5yjf | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2018-03-21 | VAL | A:134 | A:114 | 0.0 | 0.0 | H | -70.9 | -36.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.962 |
CG1 |
O |
||
| VAL | B:134 | B:114 | 1.0 | 0.006 | H | -68.3 | -40.1 | NA | NA | NA | |||||||||||||
| VAL | C:134 | C:114 | 3.0 | 0.019 | H | -58.4 | -50.8 | NA | NA | NA | |||||||||||||
| VAL | D:134 | D:114 | 1.0 | 0.006 | H | -71.5 | -40.3 | NA | NA | NA | |||||||||||||
| 2iip | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2006-10-10 | VAL | A:133 | A:114 | 1.0 | 0.006 | H | -61.4 | -46.2 | 1.0 | 0.006 | 0.0 |
HOH |
3.598 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 1.0 | 0.006 | H | -67.5 | -41.4 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -68.5 | -50.4 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -75.7 | -42.1 | NA | NA | NA | |||||||||||||
| 3rod | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2011-09-07 | VAL | A:133 | A:114 | 2.0 | 0.013 | H | -67.4 | -40.6 | 2.0 | 0.013 | 0.0 |
HOH |
7.903 |
O |
O |
||
| VAL | B:133 | B:114 | 1.0 | 0.006 | H | -64.6 | -40.0 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 1.0 | 0.006 | H | -65.2 | -41.8 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 1.0 | 0.006 | H | -67.4 | -37.6 | NA | NA | NA | |||||||||||||
| 6b1a | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2018-01-31 | VAL | A:133 | A:114 | 1.0 | 0.006 | H | -65.9 | -44.9 | 1.0 | 0.006 | 0.0 |
HOH |
3.776 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 0.0 | 0.0 | H | -70.2 | -34.7 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -71.9 | -39.7 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -69.0 | -41.5 | NA | NA | NA | |||||||||||||
| 6chh | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2018-06-13 | VAL | A:133 | A:114 | 1.0 | 0.006 | H | -65.8 | -43.1 | 1.0 | 0.006 | 0.0 |
HOH |
3.806 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 0.0 | 0.0 | H | -70.2 | -37.1 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -72.9 | -39.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.648 |
CG2 |
O |
|||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -68.3 | -40.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.636 |
CG2 |
O |
|||||||||
| 6orr | 1 | Q6FH49 | 98.86 | 0.0 |
X-RAY |
2019-10-23 | VAL | A:133 | A:114 | 1.0 | 0.006 | H | -67.4 | -35.5 | 1.0 | 0.006 | 0.0 |
HOH |
4.708 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 0.0 | 0.0 | H | -68.3 | -35.9 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -68.2 | -37.1 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -67.9 | -36.5 | NA | NA | NA | |||||||||||||
| 6pve | 1 | Q6FH49 | 98.86 | 0.0 |
X-RAY |
2019-11-27 | VAL | A:133 | A:114 | 0.0 | 0.0 | H | -67.1 | -37.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.694 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 2.0 | 0.013 | H | -67.6 | -38.3 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -67.6 | -39.0 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 1.0 | 0.006 | H | -68.9 | -37.7 | NA | NA | NA | |||||||||||||
| 6pvs | 1 | Q6FH49 | 98.86 | 0.0 |
X-RAY |
2019-11-27 | VAL | A:133 | A:114 | 0.0 | 0.0 | H | -73.9 | -34.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.672 |
C |
O |
||
| VAL | B:133 | B:114 | 3.0 | 0.019 | H | -74.4 | -37.2 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 1.0 | 0.006 | H | -74.2 | -33.4 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -71.5 | -34.2 | NA | NA | NA | |||||||||||||
| 7bkg | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:133 | A:114 | 0.0 | 0.0 | H | -65.6 | -39.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.536 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 1.0 | 0.006 | H | -63.7 | -39.0 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 1.0 | 0.006 | H | -68.7 | -38.3 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -70.8 | -34.8 | NA | NA | NA | |||||||||||||
| 7ble | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:133 | A:114 | 1.0 | 0.006 | H | -64.6 | -37.1 | 1.0 | 0.006 | 0.0 |
HOH |
3.450 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 1.0 | 0.006 | H | -72.2 | -35.9 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 1.0 | 0.006 | H | -62.1 | -44.6 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -68.7 | -43.5 | NA | NA | NA | |||||||||||||
| 7nbj | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:133 | A:114 | 1.0 | 0.006 | H | -71.2 | -36.6 | 1.0 | 0.006 | 0.0 |
HOH |
3.705 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 1.0 | 0.006 | H | -70.3 | -36.2 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -67.6 | -36.8 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -62.4 | -42.3 | NA | NA | NA | |||||||||||||
| 7nbm | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:133 | A:114 | 0.0 | 0.0 | H | -61.5 | -36.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.221 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 1.0 | 0.006 | H | -57.0 | -43.3 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -63.9 | -34.4 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -69.4 | -36.3 | NA | NA | NA | |||||||||||||
| 7nbq | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:133 | A:114 | 0.0 | 0.0 | H | -65.7 | -37.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.499 |
CG2 |
O |
||
| VAL | B:133 | B:114 | 0.0 | 0.0 | H | -63.1 | -41.0 | NA | NA | NA | |||||||||||||
| VAL | C:133 | C:114 | 0.0 | 0.0 | H | -67.9 | -41.3 | NA | NA | NA | |||||||||||||
| VAL | D:133 | D:114 | 0.0 | 0.0 | H | -69.3 | -38.3 | NA | NA | NA | |||||||||||||
| 7egu | 1 | P40261 | 99.61 | 0.0 |
X-RAY |
2021-12-15 | VAL | A:113 | A:114 | 1.0 | 0.006 | H | -64.1 | -44.0 | 1.0 | 0.006 | 0.0 |
HOH |
3.528 |
CG1 |
O |
||
| 7ehz | 1 | P40261 | 99.61 | 0.0 |
X-RAY |
2021-12-15 | VAL | A:113 | A:114 | 0.0 | 0.0 | H | -68.0 | -38.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.708 |
CG2 |
O |
||
| 5xvq | 1 | F7ERX8 | 96.97 | 0.0 |
X-RAY |
2017-08-02 | VAL | A:134 | A:114 | 0.0 | 0.0 | H | -60.3 | -51.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.682 |
CG2 |
O |
||
| VAL | B:134 | B:114 | 0.0 | 0.0 | H | -64.8 | -43.2 | NA | NA | NA | |||||||||||||
| 2i62 | 1 | O55239 | 85.5 | 7e-168 |
X-RAY |
2006-09-12 | VAL | A:115 | A:115 | 0.0 | 0.0 | H | -69.2 | -42.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.843 |
CG1 |
O |
||
| VAL | B:115 | B:115 | 1.0 | 0.006 | H | -61.8 | -46.3 | NA | NA | NA | |||||||||||||
| VAL | C:115 | C:115 | 0.0 | 0.0 | H | -64.4 | -43.2 | NA | NA | NA | |||||||||||||
| VAL | D:115 | D:115 | 0.0 | 0.0 | H | -62.1 | -47.2 | NA | NA | NA | |||||||||||||
| 5xvk | 1 | O55239 | 85.5 | 2e-167 |
X-RAY |
2017-08-02 | VAL | A:134 | A:114 | 1.0 | 0.006 | H | -63.0 | -43.4 | 1.0 | 0.006 | 0.0 |
HOH |
3.665 |
CG2 |
O |
||
| VAL | B:134 | B:114 | 0.0 | 0.0 | H | -66.5 | -44.7 | NA | NA | NA | |||||||||||||
| 5yji | 1 | O55239 | 85.5 | 2e-167 |
X-RAY |
2018-03-21 | VAL | A:134 | A:114 | 1.0 | 0.006 | H | -64.6 | -44.1 | 1.0 | 0.006 | 0.0 |
HOH |
3.742 |
CG2 |
O |
||
| VAL | B:134 | B:114 | 0.0 | 0.0 | H | -62.4 | -47.5 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p40261-f1 | 1 | P40261 | 100.0 | 0.0 | VAL | A:114 | A:114 | 1.0 | 0.006 | H | -68.2 | -42.9 | |