Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 114182838 . A C CCDS8368.1:NM_006169.2:c.434cAg>cCg_NP_006160.1:p.145Q>P Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5yjf 1 P40261 98.86 0.0 X-RAY
 2018-03-21 GLN A:165 A:145 101.0 0.561 S -81.4 141.5 101.0 0.561 0.0 SAH
HOH
 6.615
6.273
 N
C
 N6
O
GLN B:165 B:145 108.0 0.6 S -83.8 135.4 NA NA NA
GLN C:165 C:145 94.0 0.522 S -89.9 134.2 NA NA NA
GLN D:165 D:145 99.0 0.55 S -87.0 138.5 NA NA NA
2iip 1 P40261 98.86 0.0 X-RAY
 2006-10-10 GLN A:164 A:145 88.0 0.489 S -102.7 142.9 88.0 0.489 0.0 SAH
HOH
 6.724
3.533
 N
CA
 N6
O
GLN B:164 B:145 98.0 0.544 S -108.3 138.8 NA NA NA
GLN C:164 C:145 93.0 0.517 S -101.4 140.2 NA NA NA
GLN D:164 D:145 93.0 0.517 S -94.4 136.0 NA NA NA
3rod 1 P40261 98.86 0.0 X-RAY
 2011-09-07 GLN A:164 A:145 110.0 0.611 S -126.1 133.3 110.0 0.611 0.0 SAH
HOH
 6.862
6.004
 N
O
 N6
O
GLN B:164 B:145 112.0 0.622 S -86.5 141.9 NA NA NA
GLN C:164 C:145 103.0 0.572 S -66.1 143.8 NA NA NA
GLN D:164 D:145 98.0 0.544 S -120.5 144.4 NA NA NA
6b1a 1 P40261 98.86 0.0 X-RAY
 2018-01-31 GLN A:164 A:145 94.0 0.522 S -102.0 145.3 94.0 0.522 0.0 C8J
HOH
 6.626
3.598
 N
OE1
 N6
O
GLN B:164 B:145 100.0 0.556 S -110.3 144.7 NA NA NA
GLN C:164 C:145 97.0 0.539 S -89.6 147.6 NA NA NA
GLN D:164 D:145 100.0 0.556 S -88.7 147.6 NA NA NA
6chh 1 P40261 98.86 0.0 X-RAY
 2018-06-13 GLN A:164 A:145 94.0 0.522 S -102.5 145.0 94.0 0.522 0.0 F0P
HOH
 6.630
3.609
 N
OE1
 N6
O
GLN B:164 B:145 101.0 0.561 S -115.3 144.5 NA NA NA
GLN C:164 C:145 97.0 0.539 S -88.5 148.9 97.0 0.539 0.0 F0P
HOH
 6.710
3.141
 N
OE1
 N6
O
GLN D:164 D:145 99.0 0.55 S -85.4 147.9 99.0 0.55 0.0 F0P
HOH
 6.519
2.794
 N
OE1
 N6
O
6orr 1 Q6FH49 98.86 0.0 X-RAY
 2019-10-23 GLN A:164 A:145 93.0 0.517 S -97.1 148.3 93.0 0.517 0.0 N37
HOH
 6.751
6.392
 N
O
 N4
O
GLN B:164 B:145 94.0 0.522 S -97.3 148.8 NA NA NA
GLN C:164 C:145 92.0 0.511 S -105.6 148.6 NA NA NA
GLN D:164 D:145 94.0 0.522 S -98.5 148.5 NA NA NA
6pve 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 GLN A:164 A:145 101.0 0.561 S -101.9 146.8 101.0 0.561 0.0 OZP
HOH
 6.612
3.460
 N
CA
 N17
O
GLN B:164 B:145 98.0 0.544 S -101.7 146.3 NA NA NA
GLN C:164 C:145 92.0 0.511 S -102.1 148.5 NA NA NA
GLN D:164 D:145 92.0 0.511 S -101.2 145.9 NA NA NA
6pvs 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 GLN A:164 A:145 100.0 0.556 S -108.2 148.7 100.0 0.556 0.0 P0V
HOH
 6.272
3.494
 N
C
 H171
O
GLN B:164 B:145 97.0 0.539 S -108.6 146.1 NA NA NA
GLN C:164 C:145 100.0 0.556 S -108.7 151.4 NA NA NA
GLN D:164 D:145 102.0 0.567 S -109.6 149.3 NA NA NA
7bkg 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLN A:164 A:145 101.0 0.561 S -92.9 141.2 101.0 0.561 0.0 SAH
HOH
 6.774
3.548
 N
CB
 N6
O
GLN B:164 B:145 99.0 0.55 S -100.4 139.6 NA NA NA
GLN C:164 C:145 94.0 0.522 S -94.3 141.1 NA NA NA
GLN D:164 D:145 94.0 0.522 S -94.3 138.8 NA NA NA
7ble 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLN A:164 A:145 104.0 0.578 S -117.0 137.3 104.0 0.578 0.0 SAH
HOH
 6.961
3.429
 N
OE1
 N6
O
GLN B:164 B:145 109.0 0.606 S -79.3 141.2 NA NA NA
GLN C:164 C:145 94.0 0.522 S -88.6 144.3 NA NA NA
GLN D:164 D:145 94.0 0.522 S -73.6 141.7 NA NA NA
7nbj 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLN A:164 A:145 100.0 0.556 S -96.2 148.2 100.0 0.556 0.0 U7H
GOL
HOH
 7.034
3.825
3.499
 N
CB
CB
 C34
O3
O
GLN B:164 B:145 93.0 0.517 S -104.1 143.2 NA NA NA
GLN C:164 C:145 91.0 0.506 S -94.4 144.0 NA NA NA
GLN D:164 D:145 93.0 0.517 S -96.4 140.7 NA NA NA
7nbm 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLN A:164 A:145 95.0 0.528 S -139.3 133.7 95.0 0.528 0.0 U7K
HOH
 6.842
4.742
 N
O
 C29
O
GLN B:164 B:145 102.0 0.567 S -86.0 151.3 NA NA NA
GLN C:164 C:145 93.0 0.517 S -81.1 141.6 NA NA NA
GLN D:164 D:145 103.0 0.572 S -82.1 146.8 NA NA NA
7nbq 1 P40261 98.86 0.0 X-RAY
 2021-03-17 GLN A:164 A:145 99.0 0.55 S -100.6 140.3 99.0 0.55 0.0 SAH
HOH
 6.704
3.819
 N
CA
 N6
O
GLN B:164 B:145 99.0 0.55 S -107.2 139.0 NA NA NA
GLN C:164 C:145 97.0 0.539 S -95.6 137.5 NA NA NA
GLN D:164 D:145 97.0 0.539 S -88.8 142.6 NA NA NA
7egu 1 P40261 99.61 0.0 X-RAY
 2021-12-15 GLN A:144 A:145 106.0 0.589 S -92.4 134.9 106.0 0.589 0.0 HOH
 3.210
 OE1
 O
7ehz 1 P40261 99.61 0.0 X-RAY
 2021-12-15 GLN A:144 A:145 102.0 0.567 S -85.9 145.3 102.0 0.567 0.0 HOH
 6.118
 O
 O
5xvq 1 F7ERX8 96.97 0.0 X-RAY
 2017-08-02 GLN A:165 A:145 91.0 0.506 S -92.8 134.0 91.0 0.506 0.0 SAH
HOH
 6.709
3.291
 N
NE2
 N6
O
GLN B:165 B:145 98.0 0.544 S -99.2 134.7 NA NA NA
2i62 1 O55239 85.5 7e-168 X-RAY
 2006-09-12 GLN A:146 A:146 95.0 0.528 S -98.1 137.8 95.0 0.528 0.0 SAH
HOH
 6.882
2.764
 N
OE1
 N6
O
GLN B:146 B:146 97.0 0.539 S -97.2 139.0 NA NA NA
GLN C:146 C:146 94.0 0.522 S -94.2 144.7 NA NA NA
GLN D:146 D:146 93.0 0.517 S -99.7 144.6 NA NA NA
5xvk 1 O55239 85.5 2e-167 X-RAY
 2017-08-02 GLN A:165 A:145 94.0 0.522 S -102.5 143.3 94.0 0.522 0.0 SAH
HOH
 6.709
3.614
 N
CA
 N6
O
GLN B:165 B:145 96.0 0.533 S -93.4 144.4 NA NA NA
5yji 1 O55239 85.5 2e-167 X-RAY
 2018-03-21 GLN A:165 A:145 97.0 0.539 S -99.5 144.6 97.0 0.539 0.0 SAH
HOH
 6.681
3.714
 N
OE1
 N6
O
GLN B:165 B:145 99.0 0.55 S -91.4 149.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p40261-f1 1 P40261 100.0 0.0 GLN A:145 A:145 96.0 0.533 S -85.5 144.9