Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 114182882 | . | G | A | CCDS8368.1:NM_006169.2:c.478Gtg>Atg_NP_006160.1:p.160V>M | Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5yjf | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2018-03-21 | VAL | A:180 | A:160 | 0.0 | 0.0 | E | -123.1 | 126.0 | 0.0 | 0.0 | 0.0 |
HOH |
9.054 |
O |
O |
||
| VAL | B:180 | B:160 | 1.0 | 0.006 | E | -108.9 | 125.4 | NA | NA | NA | |||||||||||||
| VAL | C:180 | C:160 | 0.0 | 0.0 | E | -125.0 | 124.1 | NA | NA | NA | |||||||||||||
| VAL | D:180 | D:160 | 0.0 | 0.0 | E | -116.1 | 125.8 | NA | NA | NA | |||||||||||||
| 2iip | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2006-10-10 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -108.0 | 117.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.912 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -117.0 | 119.0 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -124.0 | 122.7 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -113.9 | 129.1 | NA | NA | NA | |||||||||||||
| 3rod | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2011-09-07 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -103.5 | 134.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.780 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -107.0 | 128.4 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -100.7 | 131.3 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 1.0 | 0.006 | E | -111.2 | 142.5 | NA | NA | NA | |||||||||||||
| 6b1a | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2018-01-31 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -116.7 | 127.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.585 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -117.4 | 126.2 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 1.0 | 0.006 | E | -117.1 | 132.3 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -114.5 | 125.1 | NA | NA | NA | |||||||||||||
| 6chh | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2018-06-13 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -116.6 | 127.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.566 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -118.8 | 126.0 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -117.4 | 132.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.647 |
CG2 |
O |
|||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -113.1 | 125.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.997 |
C |
O |
|||||||||
| 6orr | 1 | Q6FH49 | 98.86 | 0.0 |
X-RAY |
2019-10-23 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -119.2 | 123.9 | 0.0 | 0.0 | 0.0 |
HOH |
7.947 |
C |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -119.4 | 125.9 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -125.5 | 118.5 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -119.0 | 124.1 | NA | NA | NA | |||||||||||||
| 6pve | 1 | Q6FH49 | 98.86 | 0.0 |
X-RAY |
2019-11-27 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -118.8 | 125.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.765 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -117.1 | 125.9 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -119.3 | 123.7 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -119.5 | 123.5 | NA | NA | NA | |||||||||||||
| 6pvs | 1 | Q6FH49 | 98.86 | 0.0 |
X-RAY |
2019-11-27 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -125.5 | 134.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.259 |
N |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -122.7 | 135.3 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 1.0 | 0.006 | E | -121.6 | 132.0 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -123.8 | 135.8 | NA | NA | NA | |||||||||||||
| 7bkg | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -119.4 | 121.3 | 0.0 | 0.0 | 0.0 |
HOH |
6.668 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -124.8 | 113.4 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -121.8 | 122.7 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -118.3 | 126.2 | NA | NA | NA | |||||||||||||
| 7ble | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -128.3 | 113.9 | 0.0 | 0.0 | 0.0 |
HOH |
8.239 |
C |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -109.9 | 115.5 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -124.8 | 117.9 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -122.6 | 127.2 | NA | NA | NA | |||||||||||||
| 7nbj | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -126.4 | 117.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.675 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -120.2 | 116.2 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -118.2 | 123.0 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -116.6 | 123.9 | NA | NA | NA | |||||||||||||
| 7nbm | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -128.2 | 116.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.868 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -122.0 | 122.9 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 1.0 | 0.006 | E | -126.5 | 122.8 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -100.5 | 117.2 | NA | NA | NA | |||||||||||||
| 7nbq | 1 | P40261 | 98.86 | 0.0 |
X-RAY |
2021-03-17 | VAL | A:179 | A:160 | 0.0 | 0.0 | E | -132.5 | 113.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.529 |
CG2 |
O |
||
| VAL | B:179 | B:160 | 0.0 | 0.0 | E | -123.9 | 119.1 | NA | NA | NA | |||||||||||||
| VAL | C:179 | C:160 | 0.0 | 0.0 | E | -118.8 | 121.0 | NA | NA | NA | |||||||||||||
| VAL | D:179 | D:160 | 0.0 | 0.0 | E | -123.5 | 120.1 | NA | NA | NA | |||||||||||||
| 7egu | 1 | P40261 | 99.61 | 0.0 |
X-RAY |
2021-12-15 | VAL | A:159 | A:160 | 0.0 | 0.0 | E | -122.2 | 131.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.560 |
CG2 |
O |
||
| 7ehz | 1 | P40261 | 99.61 | 0.0 |
X-RAY |
2021-12-15 | VAL | A:159 | A:160 | 0.0 | 0.0 | E | -118.0 | 122.1 | 0.0 | 0.0 | 0.0 |
HOH |
7.641 |
C |
O |
||
| 5xvq | 1 | F7ERX8 | 96.97 | 0.0 |
X-RAY |
2017-08-02 | LEU | A:180 | A:160 | 2.0 | 0.012 | E | -112.9 | 126.0 | 2.0 | 0.012 | 0.0 |
GOL HOH |
8.257 6.209 |
N CD1 |
O2 O |
||
| LEU | B:180 | B:160 | 2.0 | 0.012 | E | -103.5 | 130.1 | NA | NA | NA | |||||||||||||
| 2i62 | 1 | O55239 | 85.5 | 7e-168 |
X-RAY |
2006-09-12 | LEU | A:161 | A:161 | 1.0 | 0.006 | E | -108.5 | 133.6 | 1.0 | 0.006 | 0.0 |
HOH |
6.415 |
CD2 |
O |
||
| LEU | B:161 | B:161 | 0.0 | 0.0 | E | -108.8 | 122.2 | NA | NA | NA | |||||||||||||
| LEU | C:161 | C:161 | 2.0 | 0.012 | E | -110.5 | 124.1 | NA | NA | NA | |||||||||||||
| LEU | D:161 | D:161 | 0.0 | 0.0 | E | -113.5 | 120.5 | NA | NA | NA | |||||||||||||
| 5xvk | 1 | O55239 | 85.5 | 2e-167 |
X-RAY |
2017-08-02 | LEU | A:180 | A:160 | 1.0 | 0.006 | E | -112.0 | 125.9 | 1.0 | 0.006 | 0.0 |
HOH |
6.352 |
CD2 |
O |
||
| LEU | B:180 | B:160 | 0.0 | 0.0 | E | -112.6 | 130.6 | NA | NA | NA | |||||||||||||
| 5yji | 1 | O55239 | 85.5 | 2e-167 |
X-RAY |
2018-03-21 | LEU | A:180 | A:160 | 0.0 | 0.0 | E | -119.0 | 119.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.578 |
CD2 |
O |
||
| LEU | B:180 | B:160 | 2.0 | 0.012 | E | -112.3 | 129.6 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p40261-f1 | 1 | P40261 | 100.0 | 0.0 | VAL | A:160 | A:160 | 0.0 | 0.0 | E | -115.1 | 123.0 | |