Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 114182940 . C A CCDS8368.1:NM_006169.2:c.536gCg>gAg_NP_006160.1:p.179A>E Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5yjf 1 P40261 98.86 0.0 X-RAY
 2018-03-21 ALA A:199 A:179 1.0 0.009 H -60.8 -43.4 1.0 0.009 0.0 SAH
HOH
 7.801
6.059
 CB
N
 N6
O
ALA B:199 B:179 0.0 0.0 H -53.1 -49.0 NA NA NA
ALA C:199 C:179 0.0 0.0 H -60.6 -38.1 NA NA NA
ALA D:199 D:179 0.0 0.0 H -63.2 -48.3 NA NA NA
2iip 1 P40261 98.86 0.0 X-RAY
 2006-10-10 ALA A:198 A:179 0.0 0.0 H -62.5 -41.3 0.0 0.0 0.0 SAH
HOH
 7.673
5.139
 CB
N
 N6
O
ALA B:198 B:179 0.0 0.0 H -57.4 -41.6 NA NA NA
ALA C:198 C:179 0.0 0.0 H -47.8 -43.1 NA NA NA
ALA D:198 D:179 0.0 0.0 H -52.3 -39.3 NA NA NA
3rod 1 P40261 98.86 0.0 X-RAY
 2011-09-07 ALA A:198 A:179 0.0 0.0 H -50.2 -57.6 0.0 0.0 0.0 SAH
HOH
 7.861
9.226
 CB
O
 N6
O
ALA B:198 B:179 0.0 0.0 H -52.8 -44.3 NA NA NA
ALA C:198 C:179 1.0 0.009 H -40.0 -50.7 NA NA NA
ALA D:198 D:179 0.0 0.0 H -42.6 -50.9 NA NA NA
6b1a 1 P40261 98.86 0.0 X-RAY
 2018-01-31 ALA A:198 A:179 0.0 0.0 H -59.4 -45.0 0.0 0.0 0.0 C8J
HOH
 7.692
5.350
 CB
N
 N1
O
ALA B:198 B:179 0.0 0.0 H -61.3 -42.8 NA NA NA
ALA C:198 C:179 0.0 0.0 H -57.8 -45.1 NA NA NA
ALA D:198 D:179 0.0 0.0 H -58.2 -38.2 NA NA NA
6chh 1 P40261 98.86 0.0 X-RAY
 2018-06-13 ALA A:198 A:179 0.0 0.0 H -58.6 -46.7 0.0 0.0 0.0 F0P
HOH
 7.697
5.381
 CB
N
 N1
O
ALA B:198 B:179 0.0 0.0 H -63.4 -41.8 NA NA NA
ALA C:198 C:179 0.0 0.0 H -57.8 -45.1 0.0 0.0 0.0 F0P
HOH
 7.674
5.136
 CB
N
 N6
O
ALA D:198 D:179 0.0 0.0 H -58.9 -38.0 0.0 0.0 0.0 F0P
HOH
 7.413
8.338
 CB
CB
 N6
O
6orr 1 Q6FH49 98.86 0.0 X-RAY
 2019-10-23 ALA A:198 A:179 0.0 0.0 H -61.4 -40.8 0.0 0.0 0.0 N37
GOL
HOH
 7.724
9.733
9.052
 CB
N
CB
 N4
C3
O
ALA B:198 B:179 0.0 0.0 H -61.7 -40.8 NA NA NA
ALA C:198 C:179 0.0 0.0 H -65.7 -43.5 NA NA NA
ALA D:198 D:179 1.0 0.009 H -60.6 -39.4 NA NA NA
6pve 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 ALA A:198 A:179 0.0 0.0 H -61.6 -40.5 0.0 0.0 0.0 OZP
HOH
 7.757
5.266
 CB
N
 N17
O
ALA B:198 B:179 0.0 0.0 H -60.6 -40.1 NA NA NA
ALA C:198 C:179 0.0 0.0 H -70.6 -40.3 NA NA NA
ALA D:198 D:179 0.0 0.0 H -61.1 -39.7 NA NA NA
6pvs 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 ALA A:198 A:179 1.0 0.009 H -67.2 -38.5 1.0 0.009 0.0 P0V
HOH
 6.863
4.562
 CB
N
 H171
O
ALA B:198 B:179 0.0 0.0 H -70.8 -41.3 NA NA NA
ALA C:198 C:179 0.0 0.0 H -72.3 -37.6 NA NA NA
ALA D:198 D:179 0.0 0.0 H -71.1 -40.6 NA NA NA
7bkg 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ALA A:198 A:179 0.0 0.0 H -64.1 -40.4 0.0 0.0 0.0 SAH
HOH
 7.555
7.662
 CB
N
 N6
O
ALA B:198 B:179 0.0 0.0 H -65.7 -39.9 NA NA NA
ALA C:198 C:179 0.0 0.0 H -56.4 -40.3 NA NA NA
ALA D:198 D:179 0.0 0.0 H -62.5 -40.4 NA NA NA
7ble 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ALA A:198 A:179 0.0 0.0 H -66.2 -30.6 0.0 0.0 0.0 SAH
HOH
 7.707
9.273
 CB
CB
 N6
O
ALA B:198 B:179 0.0 0.0 H -63.2 -39.7 NA NA NA
ALA C:198 C:179 0.0 0.0 H -58.7 -49.7 NA NA NA
ALA D:198 D:179 1.0 0.009 H -51.1 -44.2 NA NA NA
7nbj 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ALA A:198 A:179 0.0 0.0 H -62.5 -39.1 0.0 0.0 0.0 U7H
HOH
 7.713
5.382
 CB
N
 N33
O
ALA B:198 B:179 0.0 0.0 H -57.5 -38.9 NA NA NA
ALA C:198 C:179 0.0 0.0 H -62.6 -38.9 NA NA NA
ALA D:198 D:179 0.0 0.0 H -63.6 -42.0 NA NA NA
7nbm 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ALA A:198 A:179 0.0 0.0 H -57.8 -25.4 0.0 0.0 0.0 U7K
HOH
 7.601
7.224
 CB
O
 N33
O
ALA B:198 B:179 0.0 0.0 H -62.6 -36.8 NA NA NA
ALA C:198 C:179 0.0 0.0 H -68.2 -38.0 NA NA NA
ALA D:198 D:179 0.0 0.0 H -58.2 -45.4 NA NA NA
7nbq 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ALA A:198 A:179 0.0 0.0 H -64.3 -36.0 0.0 0.0 0.0 SAH
HOH
 7.576
7.154
 CB
O
 N6
O
ALA B:198 B:179 1.0 0.009 H -59.1 -38.6 NA NA NA
ALA C:198 C:179 0.0 0.0 H -61.4 -37.2 NA NA NA
ALA D:198 D:179 0.0 0.0 H -59.1 -34.8 NA NA NA
7egu 1 P40261 99.61 0.0 X-RAY
 2021-12-15 ALA A:178 A:179 2.0 0.017 H -58.2 -43.9 2.0 0.017 0.0 HOH
 5.644
 N
 O
7ehz 1 P40261 99.61 0.0 X-RAY
 2021-12-15 ALA A:178 A:179 0.0 0.0 H -42.3 -52.3 0.0 0.0 0.0 HOH
 9.543
 CB
 O
5xvq 1 F7ERX8 96.97 0.0 X-RAY
 2017-08-02 ALA A:199 A:179 1.0 0.009 H -59.5 -38.4 1.0 0.009 0.0 SAH
HOH
 7.829
6.208
 CB
N
 N6
O
ALA B:199 B:179 0.0 0.0 H -64.0 -33.0 NA NA NA
2i62 1 O55239 85.5 7e-168 X-RAY
 2006-09-12 ALA A:180 A:180 1.0 0.009 H -55.0 -44.2 1.0 0.009 0.0 SAH
HOH
 7.813
3.694
 CB
N
 N6
O
ALA B:180 B:180 2.0 0.017 H -56.7 -45.2 NA NA NA
ALA C:180 C:180 1.0 0.009 H -59.6 -38.0 NA NA NA
ALA D:180 D:180 2.0 0.017 H -57.4 -43.1 NA NA NA
5xvk 1 O55239 85.5 2e-167 X-RAY
 2017-08-02 ALA A:199 A:179 1.0 0.009 H -59.2 -41.2 1.0 0.009 0.0 SAH
HOH
 7.704
3.744
 CB
N
 N6
O
ALA B:199 B:179 1.0 0.009 H -59.7 -39.2 NA NA NA
5yji 1 O55239 85.5 2e-167 X-RAY
 2018-03-21 ALA A:199 A:179 2.0 0.017 H -59.1 -43.2 2.0 0.017 0.0 SAH
HOH
 7.790
3.730
 CB
N
 N6
O
ALA B:199 B:179 1.0 0.009 H -51.1 -45.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p40261-f1 1 P40261 100.0 0.0 ALA A:179 A:179 0.0 0.0 H -58.7 -45.2