Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 114182950 . C A CCDS8368.1:NM_006169.2:c.546aaC>aaA_NP_006160.1:p.182N>K Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5yjf 1 P40261 98.86 0.0 X-RAY
 2018-03-21 ASN A:202 A:182 20.0 0.125 H -55.0 -46.6 20.0 0.125 0.0 SAH
HOH
 8.812
4.705
 ND2
ND2
 N6
O
ASN B:202 B:182 20.0 0.125 H -64.9 -40.0 NA NA NA
ASN C:202 C:182 25.0 0.156 H -61.5 -44.4 NA NA NA
ASN D:202 D:182 22.0 0.138 H -48.1 -43.0 NA NA NA
2iip 1 P40261 98.86 0.0 X-RAY
 2006-10-10 ASN A:201 A:182 24.0 0.15 H -52.3 -42.1 24.0 0.15 0.0 SAH
HOH
 8.974
2.815
 ND2
ND2
 N6
O
ASN B:201 B:182 26.0 0.163 H -62.7 -41.8 NA NA NA
ASN C:201 C:182 22.0 0.138 H -61.0 -44.1 NA NA NA
ASN D:201 D:182 22.0 0.138 H -50.1 -50.0 NA NA NA
3rod 1 P40261 98.86 0.0 X-RAY
 2011-09-07 ASN A:201 A:182 21.0 0.131 H -67.0 -36.9 21.0 0.131 0.0 SAH
HOH
 9.245
4.630
 ND2
O
 N6
O
ASN B:201 B:182 19.0 0.119 H -75.0 -37.0 NA NA NA
ASN C:201 C:182 11.0 0.069 H -62.3 -34.3 NA NA NA
ASN D:201 D:182 19.0 0.119 H -48.1 -49.8 NA NA NA
6b1a 1 P40261 98.86 0.0 X-RAY
 2018-01-31 ASN A:201 A:182 21.0 0.131 H -54.8 -46.0 21.0 0.131 0.0 C8J
HOH
 8.895
2.767
 OD1
OD1
 N6
O
ASN B:201 B:182 22.0 0.138 H -49.6 -51.4 NA NA NA
ASN C:201 C:182 22.0 0.138 H -53.9 -44.8 NA NA NA
ASN D:201 D:182 21.0 0.131 H -59.4 -42.5 NA NA NA
6chh 1 P40261 98.86 0.0 X-RAY
 2018-06-13 ASN A:201 A:182 21.0 0.131 H -58.6 -45.8 21.0 0.131 0.0 F0P
HOH
 8.862
2.845
 ND2
ND2
 N6
O
ASN B:201 B:182 22.0 0.138 H -50.8 -52.4 NA NA NA
ASN C:201 C:182 22.0 0.138 H -55.4 -46.8 22.0 0.138 0.0 F0P
HOH
 8.724
2.898
 ND2
ND2
 N6
O
ASN D:201 D:182 21.0 0.131 H -59.8 -41.6 21.0 0.131 0.0 F0P
HOH
 8.628
4.902
 ND2
O
 N6
O
6orr 1 Q6FH49 98.86 0.0 X-RAY
 2019-10-23 ASN A:201 A:182 21.0 0.131 H -64.3 -41.0 21.0 0.131 0.0 N37
HOH
 8.734
4.576
 ND2
O
 N4
O
ASN B:201 B:182 23.0 0.144 H -65.4 -40.6 NA NA NA
ASN C:201 C:182 17.0 0.106 H -63.1 -40.3 NA NA NA
ASN D:201 D:182 26.0 0.163 H -64.4 -39.9 NA NA NA
6pve 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 ASN A:201 A:182 14.0 0.087 H -58.1 -42.8 14.0 0.087 0.0 OZP
HOH
 8.880
3.078
 ND2
ND2
 N17
O
ASN B:201 B:182 22.0 0.138 H -56.4 -43.0 NA NA NA
ASN C:201 C:182 22.0 0.138 H -59.1 -43.8 NA NA NA
ASN D:201 D:182 24.0 0.15 H -57.9 -43.1 NA NA NA
6pvs 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 ASN A:201 A:182 6.0 0.037 H -57.1 -42.8 6.0 0.037 0.0 P0V
HOH
 8.173
5.445
 ND2
OD1
 H171
O
ASN B:201 B:182 20.0 0.125 H -58.5 -48.2 NA NA NA
ASN C:201 C:182 20.0 0.125 H -60.2 -44.8 NA NA NA
ASN D:201 D:182 21.0 0.131 H -59.5 -43.4 NA NA NA
7bkg 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ASN A:201 A:182 23.0 0.144 H -60.7 -44.4 23.0 0.144 0.0 SAH
HOH
 8.851
4.662
 ND2
O
 N6
O
ASN B:201 B:182 25.0 0.156 H -56.3 -41.5 NA NA NA
ASN C:201 C:182 21.0 0.131 H -69.2 -39.1 NA NA NA
ASN D:201 D:182 20.0 0.125 H -63.2 -35.8 NA NA NA
7ble 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ASN A:201 A:182 26.0 0.163 H -66.9 -35.2 26.0 0.163 0.0 SAH
HOH
 9.390
6.529
 ND2
ND2
 N6
O
ASN B:201 B:182 28.0 0.175 H -58.5 -37.6 NA NA NA
ASN C:201 C:182 23.0 0.144 H -71.0 -35.7 NA NA NA
ASN D:201 D:182 20.0 0.125 H -58.0 -42.5 NA NA NA
7nbj 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ASN A:201 A:182 23.0 0.144 H -61.8 -39.2 23.0 0.144 0.0 U7H
GOL
HOH
 9.042
8.839
3.077
 ND2
ND2
OD1
 N33
O2
O
ASN B:201 B:182 23.0 0.144 H -64.5 -37.3 NA NA NA
ASN C:201 C:182 22.0 0.138 H -59.5 -39.0 NA NA NA
ASN D:201 D:182 20.0 0.125 H -59.8 -39.2 NA NA NA
7nbm 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ASN A:201 A:182 27.0 0.169 H -61.4 -35.2 27.0 0.169 0.0 U7K
HOH
 8.732
2.440
 ND2
OD1
 N33
O
ASN B:201 B:182 21.0 0.131 H -68.3 -41.3 NA NA NA
ASN C:201 C:182 24.0 0.15 H -58.6 -47.9 NA NA NA
ASN D:201 D:182 25.0 0.156 H -63.6 -25.0 NA NA NA
7nbq 1 P40261 98.86 0.0 X-RAY
 2021-03-17 ASN A:201 A:182 23.0 0.144 H -60.6 -40.6 23.0 0.144 0.0 SAH
HOH
 8.882
3.120
 ND2
OD1
 N6
O
ASN B:201 B:182 25.0 0.156 H -56.2 -42.9 NA NA NA
ASN C:201 C:182 22.0 0.138 H -60.8 -37.1 NA NA NA
ASN D:201 D:182 21.0 0.131 H -63.1 -39.0 NA NA NA
7egu 1 P40261 99.61 0.0 X-RAY
 2021-12-15 ASN A:181 A:182 21.0 0.131 H -62.2 -42.8 21.0 0.131 0.0 HOH
 2.934
 ND2
 O
7ehz 1 P40261 99.61 0.0 X-RAY
 2021-12-15 ASN A:181 A:182 18.0 0.113 H -68.3 -37.7 18.0 0.113 0.0 HOH
 5.716
 O
 O
5xvq 1 F7ERX8 96.97 0.0 X-RAY
 2017-08-02 ASN A:202 A:182 15.0 0.094 H -61.5 -47.8 15.0 0.094 0.0 SAH
HOH
 8.976
2.872
 ND2
OD1
 N6
O
ASN B:202 B:182 13.0 0.081 H -64.1 -41.3 NA NA NA
2i62 1 O55239 85.5 7e-168 X-RAY
 2006-09-12 ASN A:183 A:183 21.0 0.131 H -57.9 -49.5 21.0 0.131 0.0 SAH
HOH
 9.036
3.676
 ND2
OD1
 N6
O
ASN B:183 B:183 16.0 0.1 H -58.0 -43.7 NA NA NA
ASN C:183 C:183 0.0 0.0 H -58.6 -47.7 NA NA NA
ASN D:183 D:183 11.0 0.069 H -61.2 -45.6 NA NA NA
5xvk 1 O55239 85.5 2e-167 X-RAY
 2017-08-02 ASN A:202 A:182 14.0 0.087 H -57.6 -43.3 14.0 0.087 0.0 SAH
HOH
 8.688
3.798
 ND2
OD1
 N6
O
ASN B:202 B:182 21.0 0.131 H -59.3 -45.4 NA NA NA
5yji 1 O55239 85.5 2e-167 X-RAY
 2018-03-21 ASN A:202 A:182 18.0 0.113 H -56.1 -47.8 18.0 0.113 0.0 SAH
HOH
 8.735
4.917
 ND2
ND2
 N6
O
ASN B:202 B:182 20.0 0.125 H -57.8 -41.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p40261-f1 1 P40261 100.0 0.0 ASN A:182 A:182 21.0 0.131 H -64.7 -42.1