Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 114183048 . C A CCDS8368.1:NM_006169.2:c.644cCc>cAc_NP_006160.1:p.215P>H Homo sapiens nicotinamide N-methyltransferase (NNMT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5yjf 1 P40261 98.86 0.0 X-RAY
 2018-03-21 PRO A:235 A:215 77.0 0.531 -84.1 99.9 77.0 0.531 0.0 8WO
HOH
 7.532
3.588
 N
CA
 N2
O
PRO B:235 B:215 74.0 0.51 -83.0 73.2 NA NA NA
PRO C:235 C:215 74.0 0.51 -77.7 103.0 NA NA NA
PRO D:235 D:215 79.0 0.545 -78.1 110.9 NA NA NA
2iip 1 P40261 98.86 0.0 X-RAY
 2006-10-10 PRO A:234 A:215 67.0 0.462 -81.8 58.6 67.0 0.462 0.0 HOH
 3.488
 CA
 O
PRO B:234 B:215 68.0 0.469 -80.6 64.0 NA NA NA
PRO C:234 C:215 74.0 0.51 -83.7 55.9 NA NA NA
PRO D:234 D:215 72.0 0.497 -76.0 56.9 NA NA NA
3rod 1 P40261 98.86 0.0 X-RAY
 2011-09-07 PRO A:234 A:215 69.0 0.476 -77.5 93.7 69.0 0.476 0.0 NCA
HOH
 7.938
4.295
 N
CD
 O7
O
PRO B:234 B:215 73.0 0.503 -98.5 105.0 NA NA NA
PRO C:234 C:215 69.0 0.476 -70.3 131.2 NA NA NA
PRO D:234 D:215 70.0 0.483 -62.0 113.4 NA NA NA
6b1a 1 P40261 98.86 0.0 X-RAY
 2018-01-31 PRO A:234 A:215 61.0 0.421 -85.0 76.1 61.0 0.421 0.0 C8J
HOH
 7.554
3.708
 N
CA
 N16
O
PRO B:234 B:215 72.0 0.497 -82.5 78.0 NA NA NA
PRO C:234 C:215 70.0 0.483 -85.7 61.7 NA NA NA
PRO D:234 D:215 69.0 0.476 -87.2 66.4 NA NA NA
6chh 1 P40261 98.86 0.0 X-RAY
 2018-06-13 PRO A:234 A:215 60.0 0.414 -85.6 76.1 60.0 0.414 0.0 F0P
HOH
 7.522
3.714
 N
CA
 N16
O
PRO B:234 B:215 72.0 0.497 -83.4 83.4 NA NA NA
PRO C:234 C:215 70.0 0.483 -85.2 63.6 22.0 0.152 0.331 A:P40261:0.331
 F0P
HOH
 7.530
3.756
 N
CA
 N16
O
PRO D:234 D:215 69.0 0.476 -86.9 67.9 25.0 0.172 0.304 B:P40261:0.303
 F0P
EDO
HOH
 7.596
6.260
3.568
 N
O
CA
 N16
O1
O
6orr 1 Q6FH49 98.86 0.0 X-RAY
 2019-10-23 PRO A:234 A:215 71.0 0.49 -77.0 78.2 71.0 0.49 0.0 N37
HOH
 7.614
3.675
 N
O
 N7
O
PRO B:234 B:215 73.0 0.503 -77.1 79.0 NA NA NA
PRO C:234 C:215 58.0 0.4 -75.4 84.5 NA NA NA
PRO D:234 D:215 74.0 0.51 -76.4 78.9 NA NA NA
6pve 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 PRO A:234 A:215 63.0 0.434 -79.4 75.9 63.0 0.434 0.0 OZP
HOH
 7.467
3.400
 N
CD
 N34
O
PRO B:234 B:215 67.0 0.462 -79.7 75.8 NA NA NA
PRO C:234 C:215 65.0 0.448 -80.1 74.2 NA NA NA
PRO D:234 D:215 72.0 0.497 -80.1 74.3 NA NA NA
6pvs 1 Q6FH49 98.86 0.0 X-RAY
 2019-11-27 PRO A:234 A:215 73.0 0.503 -72.4 99.8 73.0 0.503 0.0 P0V
HOH
 6.513
3.927
 N
CA
 H341
O
PRO B:234 B:215 65.0 0.448 -71.7 98.4 NA NA NA
PRO C:234 C:215 70.0 0.483 -72.0 100.5 NA NA NA
PRO D:234 D:215 67.0 0.462 -73.3 102.7 NA NA NA
7bkg 1 P40261 98.86 0.0 X-RAY
 2021-03-17 PRO A:234 A:215 71.0 0.49 -85.5 62.5 71.0 0.49 0.0 U0Z
HOH
 8.060
3.089
 N
O
 C9
O
PRO B:234 B:215 72.0 0.497 -77.0 69.0 NA NA NA
PRO C:234 C:215 76.0 0.524 -81.0 61.5 NA NA NA
PRO D:234 D:215 75.0 0.517 -80.1 53.6 NA NA NA
7ble 1 P40261 98.86 0.0 X-RAY
 2021-03-17 PRO A:234 A:215 74.0 0.51 -75.4 75.4 74.0 0.51 0.0 U1W
HOH
 7.730
3.537
 N
O
 C10
O
PRO B:234 B:215 73.0 0.503 -85.8 85.6 NA NA NA
PRO C:234 C:215 73.0 0.503 -82.8 59.6 NA NA NA
PRO D:234 D:215 70.0 0.483 -74.2 50.2 NA NA NA
7nbj 1 P40261 98.86 0.0 X-RAY
 2021-03-17 PRO A:234 A:215 78.0 0.538 -73.7 81.4 78.0 0.538 0.0 U7H
HOH
 8.185
3.302
 N
O
 C21
O
PRO B:234 B:215 75.0 0.517 -78.2 78.4 NA NA NA
PRO C:234 C:215 76.0 0.524 -82.3 58.9 NA NA NA
PRO D:234 D:215 70.0 0.483 -79.8 55.0 NA NA NA
7nbm 1 P40261 98.86 0.0 X-RAY
 2021-03-17 PRO A:234 A:215 78.0 0.538 -70.7 86.9 78.0 0.538 0.0 U7K
HOH
 8.596
3.117
 N
O
 C10
O
PRO B:234 B:215 65.0 0.448 -86.7 61.7 NA NA NA
PRO C:234 C:215 71.0 0.49 -89.6 61.9 NA NA NA
PRO D:234 D:215 76.0 0.524 -80.8 72.8 NA NA NA
7nbq 1 P40261 98.86 0.0 X-RAY
 2021-03-17 PRO A:234 A:215 78.0 0.538 -66.4 102.7 78.0 0.538 0.0 U72
HOH
 8.154
3.718
 N
CA
 C10
O
PRO B:234 B:215 73.0 0.503 -78.5 105.6 NA NA NA
PRO C:234 C:215 75.0 0.517 -81.9 61.4 NA NA NA
PRO D:234 D:215 75.0 0.517 -78.1 54.2 NA NA NA
7egu 1 P40261 99.61 0.0 X-RAY
 2021-12-15 PRO A:214 A:215 67.0 0.462 -84.7 57.2 67.0 0.462 0.0 HOH
 3.199
 O
 O
7ehz 1 P40261 99.61 0.0 X-RAY
 2021-12-15 PRO A:214 A:215 112.0 0.772 -97.8 -25.0 112.0 0.772 0.0
5xvq 1 F7ERX8 96.97 0.0 X-RAY
 2017-08-02 PRO A:235 A:215 70.0 0.483 -75.1 77.2 70.0 0.483 0.0 8GC
HOH
 7.777
3.728
 N
CA
 N3
O
PRO B:235 B:215 71.0 0.49 -73.4 90.4 NA NA NA
2i62 1 O55239 85.5 7e-168 X-RAY
 2006-09-12 PRO A:216 A:216 74.0 0.51 -81.7 112.3 74.0 0.51 0.0 HOH
 2.596
 O
 O
PRO B:216 B:216 72.0 0.497 -79.5 114.9 NA NA NA
PRO C:216 C:216 66.0 0.455 -79.6 53.9 NA NA NA
PRO D:216 D:216 71.0 0.49 -78.5 64.3 NA NA NA
5xvk 1 O55239 85.5 2e-167 X-RAY
 2017-08-02 PRO A:235 A:215 70.0 0.483 -80.8 109.3 70.0 0.483 0.0 8GC
GOL
HOH
 7.562
8.606
2.741
 N
CG
O
 N3
O1
O
PRO B:235 B:215 69.0 0.476 -81.5 101.3 NA NA NA
5yji 1 O55239 85.5 2e-167 X-RAY
 2018-03-21 PRO A:235 A:215 70.0 0.483 -78.1 116.2 70.0 0.483 0.0 8WO
HOH
 7.573
2.957
 N
O
 N2
O
PRO B:235 B:215 73.0 0.503 -67.1 110.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p40261-f1 1 P40261 100.0 0.0 PRO A:215 A:215 71.0 0.49 -80.3 79.3