Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr11 | 12904598 | . | C | A | CCDS7810.2:NM_021961.5:c.625Cgc>Agc_NP_068780.2:p.209R>S | Homo sapiens TEA domain transcription factor 1 (TEAD1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7cmm | 1 | P28347 | 99.55 | 1e-167 |
X-RAY |
2021-02-03 | ARG | A:13 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | B:13 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| ARG | C:13 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| ARG | D:13 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4re1 | 1 | P28347 | 99.54 | 3e-166 |
X-RAY |
2014-11-19 | ARG | A:3 | A:194 | 97.0 | NA | 360.0 | 88.3 | 97.0 | NA | NA |
CL HOH |
9.479 5.141 |
O O |
CL O |
|||
| ARG | B:3 | B:194 | 167.0 | 0.742 | 360.0 | 95.7 | NA | NA | NA | ||||||||||||||
| 3kys | 1 | P28347 | 100.0 | 4e-166 |
X-RAY |
2010-02-23 | ARG | A:2 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | C:2 | C:194 | 140.0 | 0.622 | 360.0 | 96.0 | NA | NA | NA | ||||||||||||||
| 6im5 | 1 | P28347 | 99.55 | 3e-165 |
X-RAY |
2019-02-06 | ARG | A:15 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | B:15 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6hil | 1 | P28347 | 99.54 | 4e-165 |
X-RAY |
2019-04-03 | ARG | A:2 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| ARG | C:2 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| ARG | E:2 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| ARG | G:2 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 7li5 | 1 | E9PKB7 | 100.0 | 5e-164 |
X-RAY |
2022-02-02 | ARG | A:5 | A:209 | 40.0 | NA | E | -156.1 | 164.0 | 40.0 | NA | NA |
HOH |
5.491 |
CB |
O |
||
| ARG | B:5 | B:209 | 138.0 | 0.613 | E | -148.4 | 152.9 | NA | NA | NA | |||||||||||||
| 6ge3 | 1 | Q15561 | 81.74 | 5e-136 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 193.0 | 0.858 | 360.0 | 74.5 | 193.0 | 0.858 | 0.0 |
HOH |
2.700 |
N |
O |
|||
| 6gec | 1 | Q15561 | 81.74 | 5e-136 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 133.0 | 0.591 | 360.0 | 90.0 | 133.0 | 0.591 | 0.0 |
HOH |
2.722 |
NH1 |
O |
|||
| 4ln0 | 1 | Q62296 | 82.19 | 5e-136 |
X-RAY |
2014-02-26 | ARG | A:5 | A:210 | 38.0 | 0.169 | S | -116.5 | 3.1 | 38.0 | 0.169 | 0.0 |
HOH |
7.734 |
O |
O |
||
| ARG | B:5 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6l9f | 1 | Q62296 | 82.19 | 5e-136 |
X-RAY |
2019-12-11 | ARG | A:5 | A:210 | 109.0 | NA | 360.0 | -45.7 | 109.0 | NA | NA |
HOH |
2.339 |
O |
O |
|||
| ARG | C:5 | B:210 | 42.0 | 0.187 | S | -104.9 | 0.1 | NA | NA | NA | |||||||||||||
| 6sba | 1 | Q62296 | 82.19 | 1e-135 |
X-RAY |
2020-09-30 | ARG | A:4 | A:210 | 137.0 | 0.609 | 360.0 | 15.9 | 137.0 | 0.609 | 0.0 |
HOH |
3.063 |
O |
O |
|||
| 6ge5 | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 192.0 | 0.853 | 360.0 | 70.3 | 192.0 | 0.853 | 0.0 |
HOH |
2.624 |
N |
O |
|||
| 6geg | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 185.0 | 0.822 | 360.0 | 83.2 | 185.0 | 0.822 | 0.0 |
HOH |
2.590 |
N |
O |
|||
| 6gek | 1 | Q15561 | 81.28 | 2e-135 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 195.0 | 0.867 | 360.0 | 7.9 | 195.0 | 0.867 | 0.0 |
HOH |
3.747 |
NH2 |
O |
|||
| ARG | C:2 | B:217 | 143.0 | 0.636 | 360.0 | 82.0 | NA | NA | NA | ||||||||||||||
| 3jua | 1 | Q62296 | 82.11 | 4e-135 |
X-RAY |
2010-02-23 | ARG | A:3 | A:210 | 176.0 | 0.782 | S | -80.5 | -26.9 | 176.0 | 0.782 | 0.0 |
HOH |
2.749 |
NH2 |
O |
||
| ARG | C:3 | C:210 | 134.0 | 0.596 | S | -121.7 | -40.7 | NA | NA | NA | |||||||||||||
| ARG | E:3 | E:210 | 77.0 | 0.342 | S | -95.9 | -26.4 | NA | NA | NA | |||||||||||||
| ARG | G:3 | G:210 | 72.0 | 0.32 | S | -107.3 | -18.9 | NA | NA | NA | |||||||||||||
| 5xjd | 1 | Q62296 | 82.11 | 4e-135 |
X-RAY |
2018-01-24 | ARG | A:3 | A:210 | 76.0 | NA | 360.0 | -22.7 | 76.0 | NA | NA |
HOH |
3.580 |
N |
O |
|||
| ARG | B:3 | B:210 | 61.0 | NA | -108.7 | -16.8 | 61.0 | NA | NA |
HOH |
2.668 |
O |
O |
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| 6ge4 | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 148.0 | 0.658 | 360.0 | 76.0 | 148.0 | 0.658 | 0.0 |
HOH |
2.714 |
O |
O |
|||
| 6gee | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 143.0 | 0.636 | 360.0 | 101.0 | 143.0 | 0.636 | 0.0 |
HOH |
2.862 |
N |
O |
|||
| 6hik | 1 | Q15561 | 81.28 | 4e-135 |
X-RAY |
2019-04-03 | ARG | A:2 | A:217 | 40.0 | 0.178 | B | -69.8 | 141.1 | 40.0 | 0.178 | 0.0 |
PO4 HOH |
4.421 2.906 |
N NH2 |
O3 O |
||
| 5gn0 | 1 | Q62296 | 82.11 | 6e-135 |
X-RAY |
2017-05-31 | ARG | A:8 | A:210 | 27.0 | 0.12 | T | -120.9 | -15.0 | 27.0 | 0.12 | 0.0 |
HOH |
7.866 |
O |
O |
||
| ARG | B:8 | B:210 | 25.0 | 0.111 | H | -104.2 | -2.8 | NA | NA | NA | |||||||||||||
| ARG | C:8 | C:210 | 30.0 | 0.133 | T | -116.1 | -18.8 | NA | NA | NA | |||||||||||||
| ARG | D:8 | D:210 | 31.0 | 0.138 | T | -121.6 | 2.4 | NA | NA | NA | |||||||||||||
| 5oaq | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2017-10-11 | ARG | A:3 | A:217 | 188.0 | 0.836 | 360.0 | 81.3 | 188.0 | 0.836 | 0.0 |
HOH |
4.316 |
C |
O |
|||
| 6q2x | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2019-07-03 | ARG | A:3 | A:217 | 181.0 | 0.804 | 360.0 | 87.8 | 181.0 | 0.804 | 0.0 |
HOH |
4.047 |
NH1 |
O |
|||
| 6q36 | 1 | Q15561 | 81.65 | 7e-135 |
X-RAY |
2019-07-03 | ARG | A:3 | A:217 | 71.0 | 0.316 | -82.5 | 68.7 | 71.0 | 0.316 | 0.0 |
HOH |
2.642 |
O |
O |
|||
| ARG | B:3 | B:217 | 136.0 | 0.604 | 360.0 | 170.1 | 136.0 | 0.604 | 0.0 |
PO4 HOH |
9.104 2.805 |
O N |
O3 O |
||||||||||
| 5z2q | 4 | Q62296 | 82.49 | 1e-134 |
X-RAY |
2018-01-31 | ARG | D:12 | B:210 | 19.0 | 0.084 | T | -113.5 | -10.3 | 19.0 | 0.084 | 0.0 |
HOH |
3.824 |
NH2 |
O |
||
| 5z2q | 3 | Q62296 | 82.49 | 1e-134 |
X-RAY |
2018-01-31 | ARG | C:10 | A:210 | 31.0 | 0.138 | T | -126.6 | -16.4 | NA | NA | NA | ||||||
| 6ge6 | 1 | Q15561 | 80.82 | 2e-134 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 41.0 | 0.182 | B | -68.3 | 133.5 | 41.0 | 0.182 | 0.0 |
PO4 HOH |
4.255 2.782 |
N NH1 |
O3 O |
||
| 6gei | 1 | Q15561 | 80.82 | 2e-134 |
X-RAY |
2018-09-19 | ARG | A:2 | A:217 | 47.0 | 0.209 | B | -70.7 | 136.0 | 47.0 | 0.209 | 0.0 |
PO4 HOH |
4.232 2.745 |
N NH1 |
O3 O |
||
| 6sen | 1 | Q15561 | 81.19 | 4e-134 |
X-RAY |
2019-11-20 | ARG | A:3 | A:217 | 111.0 | NA | 360.0 | 48.4 | 111.0 | NA | NA |
SO4 HOH |
8.278 2.820 |
O O |
O4 O |
|||
| ARG | B:3 | B:217 | 84.0 | NA | 360.0 | -41.0 | NA | NA | NA | ||||||||||||||
| 6seo | 1 | Q15561 | 81.19 | 4e-134 |
X-RAY |
2019-11-20 | ARG | A:3 | A:217 | 53.0 | NA | -112.4 | 11.8 | 53.0 | NA | NA |
HOH |
7.208 |
CB |
O |
|||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p28347-f1 | 1 | P28347 | 100.0 | 0.0 | ARG | A:209 | A:209 | 47.0 | 0.209 | T | -123.5 | -12.5 | |