Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr11 12904623 . G A CCDS7810.2:NM_021961.5:c.650cGc>cAc_NP_068780.2:p.217R>H Homo sapiens TEA domain transcription factor 1 (TEAD1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7cmm 1 P28347 99.55 1e-167 X-RAY
 2021-02-03 ARG A:21 A:217 80.0 0.356 E -130.4 137.5 80.0 0.356 0.0
ARG B:21 B:217 112.0 0.498 E -131.0 145.0 NA NA NA
ARG C:21 C:217 90.0 0.4 E -130.4 134.7 NA NA NA
ARG D:21 D:217 109.0 0.484 E -132.2 141.3 NA NA NA
4re1 1 P28347 99.54 3e-166 X-RAY
 2014-11-19 ARG A:11 A:202 85.0 0.378 E -127.9 134.9 85.0 0.378 0.0 HOH
 2.915
 CG
 O
ARG B:11 B:202 62.0 0.276 E -125.2 135.4 NA NA NA
3kys 1 P28347 100.0 4e-166 X-RAY
 2010-02-23 ARG A:10 A:202 78.0 0.347 E -120.2 113.7 78.0 0.347 0.0
ARG C:10 C:202 78.0 0.347 E -123.0 130.6 NA NA NA
6im5 1 P28347 99.55 3e-165 X-RAY
 2019-02-06 ARG A:24 A:217 116.0 0.516 E -127.2 136.7 116.0 0.516 0.0 HOH
 4.675
 NE
 O
ARG B:24 B:217 97.0 0.431 E -129.1 141.0 NA NA NA
6hil 1 P28347 99.54 4e-165 X-RAY
 2019-04-03 ARG A:10 A:202 141.0 0.627 E -114.7 134.5 141.0 0.627 0.0 HOH
 2.972
 CB
 O
ARG C:10 D:202 104.0 0.462 E -131.8 135.7 NA NA NA
ARG E:10 B:202 117.0 0.52 E -131.7 156.6 NA NA NA
ARG G:10 C:202 101.0 0.449 E -125.0 149.5 NA NA NA
7li5 1 E9PKB7 100.0 5e-164 X-RAY
 2022-02-02 ARG A:13 A:217 128.0 0.569 E -123.4 136.3 128.0 0.569 0.0 Y2D
HOH
 8.578
3.431
 C
NH1
 H14
O
ARG B:13 B:217 100.0 0.444 E -114.4 138.9 NA NA NA
6ge3 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 TRP A:10 A:225 85.0 0.333 E -128.3 123.1 85.0 0.333 0.0 HOH
 3.105
 NE1
 O
6gec 1 Q15561 81.74 5e-136 X-RAY
 2018-09-19 TRP A:10 A:225 78.0 0.306 E -124.9 124.7 78.0 0.306 0.0 HOH
 3.264
 NE1
 O
4ln0 1 Q62296 82.19 5e-136 X-RAY
 2014-02-26 TRP A:13 A:218 29.0 0.114 E -129.1 138.3 29.0 0.114 0.0 HOH
 7.834
 CZ3
 O
TRP B:13 B:218 53.0 0.208 E -136.8 143.4 53.0 0.208 0.0
6l9f 1 Q62296 82.19 5e-136 X-RAY
 2019-12-11 TRP A:13 A:218 102.0 0.4 E -135.6 118.2 102.0 0.4 0.0 HOH
 3.715
 NE1
 O
TRP C:13 B:218 30.0 0.118 E -138.5 150.1 NA NA NA
6sba 1 Q62296 82.19 1e-135 X-RAY
 2020-09-30 TRP A:12 A:218 63.0 0.247 E -123.4 122.9 63.0 0.247 0.0 HOH
 2.398
 HE1
 O
6ge5 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 TRP A:10 A:225 86.0 0.337 E -129.9 124.2 86.0 0.337 0.0 HOH
 3.022
 NE1
 O
6geg 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 TRP A:10 A:225 82.0 0.322 E -127.4 124.4 82.0 0.322 0.0 HOH
 2.913
 NE1
 O
6gek 1 Q15561 81.28 2e-135 X-RAY
 2018-09-19 TRP A:10 A:225 48.0 0.188 E -122.8 123.7 48.0 0.188 0.0 HOH
 3.126
 NE1
 O
TRP C:10 B:225 48.0 0.188 E -120.0 117.6 NA NA NA
3jua 1 Q62296 82.11 4e-135 X-RAY
 2010-02-23 TRP A:11 A:218 78.0 0.306 E -131.3 110.7 78.0 0.306 0.0 HOH
 4.081
 CH2
 O
TRP C:11 C:218 40.0 0.157 E -128.7 117.2 NA NA NA
TRP E:11 E:218 58.0 0.227 E -118.8 120.4 NA NA NA
TRP G:11 G:218 56.0 0.22 E -143.5 127.3 NA NA NA
5xjd 1 Q62296 82.11 4e-135 X-RAY
 2018-01-24 TRP A:11 A:218 61.0 0.239 E -137.8 140.3 61.0 0.239 0.0 HOH
 5.475
 NE1
 O
TRP B:11 B:218 59.0 0.231 E -138.5 142.9 59.0 0.231 0.0 HOH
 3.342
 CD1
 O
6ge4 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 TRP A:10 A:225 57.0 0.224 E -125.8 124.9 57.0 0.224 0.0 HOH
 2.937
 NE1
 O
6gee 1 Q15561 81.28 4e-135 X-RAY
 2018-09-19 TRP A:10 A:225 84.0 0.329 E -123.9 124.6 84.0 0.329 0.0 HOH
 2.781
 NE1
 O
6hik 1 Q15561 81.28 4e-135 X-RAY
 2019-04-03 TRP A:10 A:225 61.0 0.239 E -121.5 126.1 61.0 0.239 0.0 PO4
HOH
 9.812
3.208
 NE1
CD2
 O3
O
5gn0 1 Q62296 82.11 6e-135 X-RAY
 2017-05-31 TRP A:16 A:218 13.0 0.051 E -132.6 129.0 13.0 0.051 0.0
TRP B:16 B:218 10.0 0.039 E -132.2 142.0 NA NA NA
TRP C:16 C:218 13.0 0.051 E -126.5 130.2 NA NA NA
TRP D:16 D:218 34.0 0.133 E -124.5 128.1 NA NA NA
5oaq 1 Q15561 81.65 7e-135 X-RAY
 2017-10-11 TRP A:11 A:225 64.0 0.251 E -131.2 129.1 64.0 0.251 0.0 HOH
 3.219
 NE1
 O
6q2x 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 TRP A:11 A:225 69.0 0.271 E -133.3 128.9 69.0 0.271 0.0 HOH
 3.046
 NE1
 O
6q36 1 Q15561 81.65 7e-135 X-RAY
 2019-07-03 TRP A:11 A:225 27.0 0.106 E -124.3 126.1 27.0 0.106 0.0 HOH
 3.148
 NE1
 O
TRP B:11 B:225 76.0 0.298 E -120.6 125.7 76.0 0.298 0.0 PO4
HOH
 9.989
3.238
 CZ2
NE1
 O3
O
5z2q 4 Q62296 82.49 1e-134 X-RAY
 2018-01-31 TRP D:20 B:218 27.0 0.106 E -131.3 135.0 27.0 0.106 0.0
5z2q 3 Q62296 82.49 1e-134 X-RAY
 2018-01-31 TRP C:18 A:218 30.0 0.118 E -129.5 134.5 NA NA NA
6ge6 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 TRP A:10 A:225 68.0 0.267 E -119.5 122.9 68.0 0.267 0.0 PO4
PO4
HOH
 9.855
9.926
3.748
 NE1
O
CZ2
 O3
O1
O
6gei 1 Q15561 80.82 2e-134 X-RAY
 2018-09-19 TRP A:10 A:225 62.0 0.243 E -121.5 124.6 62.0 0.243 0.0 PO4
HOH
 9.873
3.322
 NE1
CD2
 O3
O
6sen 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 TRP A:11 A:225 104.0 0.408 E -125.5 126.8 104.0 0.408 0.0 SO4
HOH
 9.939
3.430
 NE1
NE1
 O4
O
TRP B:11 B:225 131.0 0.514 E -114.4 129.3 NA NA NA
6seo 1 Q15561 81.19 4e-134 X-RAY
 2019-11-20 TRP A:11 A:225 90.0 0.353 E -134.1 126.6 90.0 0.353 0.0 HOH
 8.732
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p28347-f1 1 P28347 100.0 0.0 ARG A:217 A:217 53.0 0.236 E -121.2 145.8